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D5EBS7 (RIBL_METMS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:Mmah_1121
OrganismMethanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP) [Complete proteome] [HAMAP]
Taxonomic identifier547558 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanohalophilus

Protein attributes

Sequence length142 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 142142FAD synthase HAMAP-Rule MF_02115
PRO_0000406263

Regions

Nucleotide binding9 – 102ATP By similarity
Nucleotide binding14 – 174ATP By similarity
Nucleotide binding90 – 934ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
D5EBS7 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: D08690A95B8929B3

FASTA14216,484
        10         20         30         40         50         60 
MTRILATGTF DILHPGHLYY LEQARKYGNE LYVLVARDST IEHKPKPIVP EKQRLEMVKA 

        70         80         90        100        110        120 
LRVVDHALLG SEEDMFKPLK EVQPDIIVLG HDQVFDEKEL EDKLQKRGFN TKVVRLGKPH 

       130        140 
QCTLCSSGRI IKRILERKRT EL 

« Hide

References

[1]"The complete genome of Methanohalophilus mahii DSM 5219."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M. expand/collapse author list , Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.
Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35705 / DSM 5219 / SLP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001994 Genomic DNA. Translation: ADE36628.1.
RefSeqYP_003542273.1. NC_014002.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE36628; ADE36628; Mmah_1121.
GeneID8983288.
KEGGmmh:Mmah_1121.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAIVLGHDQ.

Enzyme and pathway databases

BioCycMMAH547558:GHP5-1158-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_METMS
AccessionPrimary (citable) accession number: D5EBS7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: June 15, 2010
Last modified: May 14, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways