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D5E898 (D5E898_METMS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase HAMAP-Rule MF_00177

EC=6.1.1.6 HAMAP-Rule MF_00177
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00177
Gene names
Name:lysS HAMAP-Rule MF_00177
Ordered Locus Names:Mmah_1891 EMBL ADE37386.1
OrganismMethanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP) [Complete proteome] [HAMAP] EMBL ADE37386.1
Taxonomic identifier547558 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanohalophilus

Protein attributes

Sequence length527 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP-Rule MF_00177

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00177.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00177 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif30 – 389"HIGH" region By similarity HAMAP-Rule MF_00177
Motif276 – 2805"KMSKS" region By similarity HAMAP-Rule MF_00177

Sequences

Sequence LengthMass (Da)Tools
D5E898 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 882460191408D300

FASTA52759,248
        10         20         30         40         50         60 
MTEITHWADV VAEETLERGN THLVATGITP SGHIHVGNMR EVVTADAAYR ALLDRDANAE 

        70         80         90        100        110        120 
LIYIADTYDP LRKVYPFLDE SYEEHVGKPL SEIPCPCGEC KNYADHFLQP FLKSLHRLGI 

       130        140        150        160        170        180 
KPEVYLADEL YKSGRYNEGI KTALKKRDKI AAILKEVSGR QPGDDWSPFN PICMQCGKIN 

       190        200        210        220        230        240 
TTRVTSFDER EETVDYTCSC GHSGTVPMQG GGKLTWRVDW PARWQILGVT VEPFGKDHAS 

       250        260        270        280        290        300 
RGGSYDTGKR IAREIFGCEP PHPIVYEWIM LGKEGAMSSS TGVVVSIADM LKVVPPEVLR 

       310        320        330        340        350        360 
YLIIRTKPEK HIRFDPAQPL LTLVDQYEKL HQTGGTSEYD RRVKELSHAS GLCHTDIPFK 

       370        380        390        400        410        420 
HMTTIHQVAH GDFDRILKIV ERAGYDTKNT ECIKQLADNV GNWLDMYAPP FAKFSVQEKL 

       430        440        450        460        470        480 
PELAATLSDK QRAFLTTLAD VLEESAELDG SDYHNLVYSA KEEGGRLHRE MEKVLGEEFT 

       490        500        510        520 
IGPKDLFKAL YISLLGQASG PKAGWFLSSL EKDFLIKRFR EAAAYRP 

« Hide

References

[1]"The complete genome of Methanohalophilus mahii DSM 5219."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M. expand/collapse author list , Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.
Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35705 / DSM 5219 / SLP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001994 Genomic DNA. Translation: ADE37386.1.
RefSeqYP_003543031.1. NC_014002.1.

3D structure databases

ProteinModelPortalD5E898.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE37386; ADE37386; Mmah_1891.
GeneID8984078.
KEGGmmh:Mmah_1891.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000226938.
KOK04566.
OMADTYDPLR.

Enzyme and pathway databases

BioCycMMAH547558:GHP5-1948-MONOMER.

Family and domain databases

Gene3D1.10.10.350. 1 hit.
2.30.30.300. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00177. Lys_tRNA_synth_class1.
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR023386. Lys-tRNA-ligase_insertion.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMSSF48163. SSF48163. 1 hit.
TIGRFAMsTIGR00467. lysS_arch. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5E898_METMS
AccessionPrimary (citable) accession number: D5E898
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 19, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)