D5E4K7 (D5E4K7_MYCCM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-2 RuleBase RU000644 HAMAP-Rule MF_00100

Gene names

Name:	infB HAMAP-Rule MF_00100 EMBL ADE19582.1
Ordered Locus Names:	MCRO_0016

Organism

Mycoplasma crocodyli (strain ATCC 51981 / MP145) [Complete proteome] [HAMAP] EMBL ADE19582.1

Taxonomic identifier

512564 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma crocodyli

Protein attributes

Sequence length	601 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity. RuleBase RU000644 HAMAP-Rule MF_00100
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00100 RuleBase RU000645.
Sequence similarities	Belongs to the IF-2 family. RuleBase RU000644 HAMAP-Rule MF_00100

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00100
Ligand	GTP-binding HAMAP-Rule MF_00100 RuleBase RU000323 Nucleotide-binding
Molecular function	Initiation factor RuleBase RU000644 HAMAP-Rule MF_00100 EMBL ADE19582.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: HAMAP translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	120 – 127	8	GTP By similarity HAMAP-Rule MF_00100
	Nucleotide binding	166 – 170	5	GTP By similarity HAMAP-Rule MF_00100
	Nucleotide binding	220 – 223	4	GTP By similarity HAMAP-Rule MF_00100
	Region	114 – 262	149	G-domain By similarity HAMAP-Rule MF_00100

Sequences

	Sequence		Length	Mass (Da)
	D5E4K7 [UniParc]. Last modified June 15, 2010. Version 1. Checksum: EA631BFFA68817A9	FASTA	601	66,244
	10 20 30 40 50 60 MKKKTNRISN VDDVKNQLSS HKTELKDGIF TFTGKMSVVD FAAKTKLNAN DIIKKFFIKG 70 80 90 100 110 120 KMYNLNHVLE EEEIAELCLE NNFEFNKETN VDASNFLDEV LFEDKTKDLV KRAPIITVMG 130 140 150 160 170 180 HVDHGKTTLI DKIRNTNVAD SETSGITQHT GAYQIKYKGA NITFIDTPGH EAFTMMRARG 190 200 210 220 230 240 AKITDIVVLV VAADDGVMPQ TKEAIEHSLA AKVPIVVFVN KMDKPNKDLD RIKGELANCN 250 260 270 280 290 300 VVIEEFGGDT QIAYGSASKG TGLDDLFDKI SILTEILDLK ANPKRYPIGT VIESRLDKGV 310 320 330 340 350 360 GSVITLIVEN GTLYKGDFIV AGSMYGRIRT LCDHAGNPVD KAEPGTPVVV SGLNYTPQAG 370 380 390 400 410 420 DRFVGFSDEK FAKKLASEKS MMDRQTNLYL KTSNTNTQGD KKVVNIILKT DVHGTSEAIK 430 440 450 460 470 480 GQIHDLSNDE AIIKVISANA GNVSNADLLL AQASNAIIFT FNAKPSVTVK QSALNLGIDL 490 500 510 520 530 540 YSHDVIYKII DDCQKLLDGL KAPVYEEKKT GIAHIIKVFF YSKVGNIAGC LVDEGVVKAN 550 560 570 580 590 600 SKVKVYRAGK LIHEGVIDSL RRELNDTKEV VKGKDFGTHI RKYNEIKVDD VLEFFEDVRV N

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome of Mycoplasma crocodyli MP145." Glass J.I., Durkin A.S., Hostetler J., Jackson J., Johnson J., May M.A., Paralanov V., Radune D., Szczypinski B., Brown D.R. Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51981 / MP145.
[2]	Ma Z., Wang X., Liu H. Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MP145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001991 Genomic DNA. Translation: ADE19582.1.
RefSeq	YP_003559700.1. NC_014014.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADE19582; ADE19582; MCRO_0016.
GeneID	8970524.
KEGG	mcd:MCRO_0016.
PATRIC	35464943. VBIMycCro43672_0016.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000076906.
KO	K02519.
OMA	NISREVI.
Enzyme and pathway databases
BioCyc	MCRO512564:GI47-244-MONOMER.
Family and domain databases
Gene3D	3.40.50.10050. 1 hit.
HAMAP	MF_00100_B. IF_2_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR006847. IF2_N. IPR005225. Small_GTP-bd_dom. IPR000178. TF_IF2_bacterial-like. IPR015760. TIF_IF2. IPR023115. TIF_IF2_dom3. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
PANTHER	PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF11987. IF-2. 1 hit. PF04760. IF2_N. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF52156. TIF_IF2_dom3. 1 hit. SSF50447. Translat_factor. 2 hits.
TIGRFAMs	TIGR00487. IF-2. 1 hit. TIGR00231. small_GTP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

D5E4K7_MYCCM

Accession

Primary (citable) accession number: D5E4K7

Entry history

Integrated into UniProtKB/TrEMBL:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)