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D5E116

- D5E116_BACMQ

UniProt

D5E116 - D5E116_BACMQ

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Protein
Submitted name: Acetolactate synthase, catabolic
Gene
alsS, BMQ_0789
Organism
Bacillus megaterium (strain ATCC 12872 / QMB1551)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. acetolactate synthase activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. butanediol metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Keywords - Ligandi

Thiamine pyrophosphateUniRule annotation

Enzyme and pathway databases

BioCyciBMEG545693:GHSY-789-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Acetolactate synthase, catabolicImported (EC:2.2.1.6Imported)
Gene namesi
Name:alsSImported
Ordered Locus Names:BMQ_0789Imported
OrganismiBacillus megaterium (strain ATCC 12872 / QMB1551)Imported
Taxonomic identifieri545693 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000000935: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the TPP enzyme family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000258447.
KOiK01652.

Family and domain databases

Gene3Di3.40.50.1220. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR012782. Acetolactate_synth_catblc.
IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR029061. THDP-binding.
IPR012000. Thiamin_PyroP_enz_cen_dom.
IPR012001. Thiamin_PyroP_enz_TPP-bd_dom.
IPR000399. TPP-bd_CS.
IPR011766. TPP_enzyme-bd_C.
[Graphical view]
PfamiPF02775. TPP_enzyme_C. 1 hit.
PF00205. TPP_enzyme_M. 1 hit.
PF02776. TPP_enzyme_N. 1 hit.
[Graphical view]
SUPFAMiSSF52467. SSF52467. 1 hit.
SSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR02418. acolac_catab. 1 hit.
PROSITEiPS00187. TPP_ENZYMES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5E116-1 [UniParc]FASTAAdd to Basket

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MMSNADTTET KKGADLLVES LASQNVPYIF GIPGAKIDGV FDVLKEKGPE    50
VIVCRHEQNA AFMAAAMGRL TGTPGVCLVT SGPGAANLAT GLVTATSEGD 100
PVVALAGAVP RADRLKKTHQ SMDNEGLFKS IAKFSVEVED AANVPEVITD 150
AFREAVSSPS GASFVSLPQD VMDNETSAST LSVLKAPTIG AANLDAVAQA 200
IHTIRTAKLP VLLLGMRASK SKAVESIRQL IAEHDLPVVE TFQGAGAVSR 250
ELETHFFGRV GLFRNQPGDV LLKHADVVLT IGYDPVEYPP SLWNSESQRS 300
IIHLDDLQAQ ADHHYQPEIE LVGDIPSTID ILADKLPHLI RSKESASFLK 350
TLKSKLEQPD DQYEFSNDTH LHPLQLIEAL QNFVEDDTTI TCDVGSHYIW 400
MARYFRSYEP QHLLFSNGMQ TLGVALPWAI SAALVRPHKK VLSLSGDGGF 450
LFSAMELETA VRLNLPIVHI IWNDQTYDMV GFQQQIKYGR KSAVEFGSVD 500
FVTLAESFGA KGFRVNSPEE FSDTLASAFR EQGPVIIDVP VDYKDNEKLN 550
TQLLPDQIN 559
Length:559
Mass (Da):60,864
Last modified:June 15, 2010 - v1
Checksum:i0CC0779D986A9BB1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001983 Genomic DNA. Translation: ADE67822.1.
RefSeqiYP_003561256.1. NC_014019.1.

Genome annotation databases

EnsemblBacteriaiADE67822; ADE67822; BMQ_0789.
GeneIDi8985227.
KEGGibmq:BMQ_0789.
PATRICi35478219. VBIBacMeg35839_0784.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001983 Genomic DNA. Translation: ADE67822.1 .
RefSeqi YP_003561256.1. NC_014019.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE67822 ; ADE67822 ; BMQ_0789 .
GeneIDi 8985227.
KEGGi bmq:BMQ_0789.
PATRICi 35478219. VBIBacMeg35839_0784.

Phylogenomic databases

HOGENOMi HOG000258447.
KOi K01652.

Enzyme and pathway databases

BioCyci BMEG545693:GHSY-789-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1220. 1 hit.
3.40.50.970. 2 hits.
InterProi IPR012782. Acetolactate_synth_catblc.
IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR029061. THDP-binding.
IPR012000. Thiamin_PyroP_enz_cen_dom.
IPR012001. Thiamin_PyroP_enz_TPP-bd_dom.
IPR000399. TPP-bd_CS.
IPR011766. TPP_enzyme-bd_C.
[Graphical view ]
Pfami PF02775. TPP_enzyme_C. 1 hit.
PF00205. TPP_enzyme_M. 1 hit.
PF02776. TPP_enzyme_N. 1 hit.
[Graphical view ]
SUPFAMi SSF52467. SSF52467. 1 hit.
SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR02418. acolac_catab. 1 hit.
PROSITEi PS00187. TPP_ENZYMES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
    Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12872 / QMB1551.

Entry informationi

Entry nameiD5E116_BACMQ
AccessioniPrimary (citable) accession number: D5E116
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: June 11, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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