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Protein
Submitted name:

PTS system N-acetylglucosamine-specific EIICBA component

Gene

nagE

Organism
Bacillus megaterium (strain ATCC 12872 / QMB1551)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Phosphotransferase systemSAAS annotation, Sugar transportSAAS annotation, Transport

Enzyme and pathway databases

BioCyciBMEG545693:GHSY-1175-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
PTS system N-acetylglucosamine-specific EIICBA componentImported (EC:2.7.1.69Imported)
Gene namesi
Name:nagEImported
Ordered Locus Names:BMQ_1175Imported
OrganismiBacillus megaterium (strain ATCC 12872 / QMB1551)Imported
Taxonomic identifieri545693 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000935 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei45 – 6218HelicalSequence analysisAdd
BLAST
Transmembranei69 – 8618HelicalSequence analysisAdd
BLAST
Transmembranei92 – 11019HelicalSequence analysisAdd
BLAST
Transmembranei130 – 15324HelicalSequence analysisAdd
BLAST
Transmembranei159 – 17820HelicalSequence analysisAdd
BLAST
Transmembranei185 – 20521HelicalSequence analysisAdd
BLAST
Transmembranei225 – 24521HelicalSequence analysisAdd
BLAST
Transmembranei257 – 27923HelicalSequence analysisAdd
BLAST
Transmembranei285 – 30824HelicalSequence analysisAdd
BLAST
Transmembranei328 – 34922HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi545693.BMQ_1175.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 361361PTS EIIC type-1InterPro annotationAdd
BLAST
Domaini380 – 46283PTS EIIB type-1InterPro annotationAdd
BLAST
Domaini496 – 600105PTS EIIA type-1InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains PTS EIIA type-1 domain.SAAS annotation
Contains PTS EIIB type-1 domain.SAAS annotation
Contains PTS EIIC type-1 domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CI1. Bacteria.
COG1263. LUCA.
COG1264. LUCA.
COG2190. LUCA.
HOGENOMiHOG000250993.
KOiK02802.
K02803.
K02804.
OMAiLMYVWPV.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR010974. PTS_IIBC_nag.
[Graphical view]
PfamiPF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
TIGR00830. PTBA. 1 hit.
TIGR01998. PTS-II-BC-nag. 1 hit.
PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5DZ44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNFLQRIGK SLMLPIAVLP AAALLLRLGQ KDLLDIPFMA QAGDAIFANL
60 70 80 90 100
ALLFALGIAV GLSKDGSGAA ALAGVVGYFV LTKGTVAIDK DINMGVLGGI
110 120 130 140 150
VSGVTAGLLY NRFSAIKLPE WLGFFAGKRF VPIITSVVML ALAGIFGVIW
160 170 180 190 200
PPIQDQINNL GTWITGAGAL GAGIYGFLNR LLIPIGLHHV LNSLVWFVFG
210 220 230 240 250
DYHGVTGDLN RFFKGDPTAG TFMSGFFPVM MFGLPAAALA MVAAAKKEKR
260 270 280 290 300
KQVSGMLIGL AVTSFLTGIT EPIEFLFMFV APLLYVIHAV LTGISMALAV
310 320 330 340 350
ALGIHAGFGF SAGAIDFFLN YGISQKPLLL AGIGIVYAVI YFVIFYTLIK
360 370 380 390 400
ALNLKTPGRE DDEEVDTSNE TIVATGDKYV DMASYFIEDL GGKENLTVID
410 420 430 440 450
NCATRLRLQV ADAGNINEAA LKRHGARGIM KLSKTNVQVI VGTEVEFVAD
460 470 480 490 500
AMNQLVKYGT ASTAAPVEQQ AVQADAHTEF VLPFEGVVKP LSEVEDQVFS
510 520 530 540 550
QKMMGDGFAI EPIEGTLVSP IDGKVMTVFP TKHAIGLKTA EGIEILIHVG
560 570 580 590 600
LDTVNLKGEG FGALVQEGDS IQQGTPLLKV DLEYVKKHAP SIVTPVVFTN
610 620
LPADKEVKLL KTGYQKQGTK DVITF
Length:625
Mass (Da):66,618
Last modified:June 15, 2010 - v1
Checksum:i17138B92E5842319
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001983 Genomic DNA. Translation: ADE68208.1.
RefSeqiWP_013055883.1. NC_014019.1.

Genome annotation databases

EnsemblBacteriaiADE68208; ADE68208; BMQ_1175.
KEGGibmq:BMQ_1175.
PATRICi35478999. VBIBacMeg35839_1174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001983 Genomic DNA. Translation: ADE68208.1.
RefSeqiWP_013055883.1. NC_014019.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi545693.BMQ_1175.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADE68208; ADE68208; BMQ_1175.
KEGGibmq:BMQ_1175.
PATRICi35478999. VBIBacMeg35839_1174.

Phylogenomic databases

eggNOGiENOG4105CI1. Bacteria.
COG1263. LUCA.
COG1264. LUCA.
COG2190. LUCA.
HOGENOMiHOG000250993.
KOiK02802.
K02803.
K02804.
OMAiLMYVWPV.

Enzyme and pathway databases

BioCyciBMEG545693:GHSY-1175-MONOMER.

Family and domain databases

Gene3Di3.30.1360.60. 1 hit.
InterProiIPR011055. Dup_hybrid_motif.
IPR018113. PTrfase_EIIB_Cys.
IPR001127. PTS_EIIA_1_perm.
IPR003352. PTS_EIIC.
IPR013013. PTS_EIIC_1.
IPR001996. PTS_IIB_1.
IPR010974. PTS_IIBC_nag.
[Graphical view]
PfamiPF00358. PTS_EIIA_1. 1 hit.
PF00367. PTS_EIIB. 1 hit.
PF02378. PTS_EIIC. 1 hit.
[Graphical view]
SUPFAMiSSF51261. SSF51261. 1 hit.
SSF55604. SSF55604. 1 hit.
TIGRFAMsiTIGR00826. EIIB_glc. 1 hit.
TIGR00830. PTBA. 1 hit.
TIGR01998. PTS-II-BC-nag. 1 hit.
PROSITEiPS51093. PTS_EIIA_TYPE_1. 1 hit.
PS00371. PTS_EIIA_TYPE_1_HIS. 1 hit.
PS51098. PTS_EIIB_TYPE_1. 1 hit.
PS01035. PTS_EIIB_TYPE_1_CYS. 1 hit.
PS51103. PTS_EIIC_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
    Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12872 / QMB1551Imported.

Entry informationi

Entry nameiD5DZ44_BACMQ
AccessioniPrimary (citable) accession number: D5DZ44
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: March 16, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.