D5DTR3 (D5DTR3_BACMQ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
MutS2 protein HAMAP-Rule MF_00092

Gene names

Name:	mutS EMBL ADE71739.1
Synonyms:	mutS2 HAMAP-Rule MF_00092
Ordered Locus Names:	BMQ_4737 EMBL ADE71739.1

Organism

Bacillus megaterium (strain ATCC 12872 / QMB1551) [Complete proteome] [HAMAP] EMBL ADE71739.1

Taxonomic identifier

545693 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus megaterium

Protein attributes

Sequence length	787 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the DNA mismatch repair MutS family. HAMAP-Rule MF_00092 RuleBase RU003756 Contains 1 Smr domain. HAMAP-Rule MF_00092 SAAS SAAS005747

Ontologies

Keywords
Ligand	ATP-binding HAMAP-Rule MF_00092 SAAS SAAS005747 DNA-binding HAMAP-Rule MF_00092 RuleBase RU003757 SAAS SAAS005747 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	maintenance of fidelity involved in DNA-dependent DNA replication Inferred from electronic annotation. Source: InterPro mismatch repair Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP damaged DNA binding Inferred from electronic annotation. Source: InterPro mismatched DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	712 – 787	76	Smr By similarity HAMAP-Rule MF_00092
	Nucleotide binding	336 – 343	8	ATP By similarity HAMAP-Rule MF_00092

Sequences

	Sequence		Length	Mass (Da)
	D5DTR3 [UniParc]. Last modified June 15, 2010. Version 1. Checksum: 9DDAEF6F70B5921D	FASTA	787	88,190
	10 20 30 40 50 60 MQSRIFHVLE FNKVKEQLQK KVASSLGREK VANLIPSTQY EEVVKWQEAT DEATTVLRLR 70 80 90 100 110 120 GNVPLGGIFD VRSSVKRAEI GGTLSSNELL DVASTIYAAR QVKQFIEQVV EDEDLQLPII 130 140 150 160 170 180 TEHIEKLMPL PEVEQTIKMS IDENGTVLDG ASDQLRGIRQ KLRSTESRIR EKLESLIRSS 190 200 210 220 230 240 SAQKMLSDAI VTIRNERFVI PVKQEYRSAY GGIVHDQSSS GATLFIEPQA IVTLNNELQE 250 260 270 280 290 300 AKVKEKQEIE RILIALTVQV AEVANELRQN VYLLGELDFM FAKGRYSHEL KASKPKMNDR 310 320 330 340 350 360 GYIKLVKAKH PLIAQEDVVA NDIELGDQYT SIVITGPNTG GKTVTLKTLG LFTLMAQAGL 370 380 390 400 410 420 QIPALDGSEM AVFKHVFADI GDEQSIEQSL STFSSHMVNI VDILQKVDHE SLVLFDELGA 430 440 450 460 470 480 GTDPQEGAAL AISILDQVYE RGARVVATTH YPELKAYGYN REGVVNASVE FDIETLSPTY 490 500 510 520 530 540 KLLIGVPGRS NAFEISKRLG LSAEVIERAK GYIGSETNKV ENMIASLEDS RRQSEHELEE 550 560 570 580 590 600 AEELRKEAQK LHKELQSQII EFNEKRDKLY EKAEEKAQAT VKAASEEAEK IISDLRKMSQ 610 620 630 640 650 660 KNYALVKEHE LIEARKRLED AVPTLEKSKK KPAAPKKQER TLQAGDEVKV LSWGQKGTLV 670 680 690 700 710 720 ERVSNNEWQV QMGIMKMKVK EKDLEYISSP KPVETKPLAT VKGKDYHVNL ELDLRGERYE 730 740 750 760 770 780 NALIRVEKYI DDALLANYPR VSIIHGKGTG ALRKGVQEYL KNHRSVKNIR FGEASEGGSG VTVVEFK

References

[1]

"Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure." Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S. Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 12872 / QMB1551.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001983 Genomic DNA. Translation: ADE71739.1.
RefSeq	YP_003565173.1. NC_014019.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADE71739; ADE71739; BMQ_4737.
GeneID	8989175.
KEGG	bmq:BMQ_4737.
PATRIC	35486246. VBIBacMeg35839_4777.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000135096.
KO	K07456.
Enzyme and pathway databases
BioCyc	BMEG545693:GHSY-4737-MONOMER.
Family and domain databases
HAMAP	MF_00092. MutS2.
InterPro	IPR005747. DNA_mismatch_repair_MutS-2. IPR000432. DNA_mismatch_repair_MutS_C. IPR007696. DNA_mismatch_repair_MutS_core. IPR027417. P-loop_NTPase. IPR002625. Smr/MutS2_C. [Graphical view]
PANTHER	PTHR11361:SF14. PTHR11361:SF14. 1 hit.
Pfam	PF05192. MutS_III. 1 hit. PF00488. MutS_V. 1 hit. PF01713. Smr. 1 hit. [Graphical view]
PIRSF	PIRSF005814. MutS_YshD. 1 hit.
SMART	SM00534. MUTSac. 1 hit. SM00533. MUTSd. 1 hit. SM00463. SMR. 1 hit. [Graphical view]
SUPFAM	SSF48334. DNA_repair_MutS_domIII. 1 hit. SSF52540. SSF52540. 1 hit.
TIGRFAMs	TIGR01069. mutS2. 1 hit.
PROSITE	PS00486. DNA_MISMATCH_REPAIR_2. 1 hit. PS50828. SMR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D5DTR3_BACMQ

Accession

Primary (citable) accession number: D5DTR3

Entry history

Integrated into UniProtKB/TrEMBL:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	May 29, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)