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Protein
Submitted name:

Folylpolyglutamate synthase

Gene

folC

Organism
Bacillus megaterium (strain ATCC 12872 / QMB1551)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionLigaseUniRule annotationImported
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Folylpolyglutamate synthaseImported (EC:6.3.2.17Imported)
Gene namesi
Name:folCImported
Ordered Locus Names:BMQ_4676Imported
OrganismiBacillus megaterium (strain ATCC 12872 / QMB1551)Imported
Taxonomic identifieri545693 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000935 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi545693.BMQ_4676.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 273Mur_ligase_MInterPro annotationAdd BLAST228
Domaini299 – 377Mur_ligase_CInterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the folylpolyglutamate synthase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DPM. Bacteria.
COG0285. LUCA.
HOGENOMiHOG000019981.
KOiK11754.
OMAiLTYFEMG.
OrthoDBiPOG091H021T.

Family and domain databases

Gene3Di3.40.1190.10. 1 hit.
InterProiView protein in InterPro
IPR001645. Folylpolyglutamate_synth.
IPR018109. Folylpolyglutamate_synth_CS.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
PANTHERiPTHR11136. PTHR11136. 1 hit.
PfamiView protein in Pfam
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
PIRSFiPIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAMiSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsiTIGR01499. folC. 1 hit.
PROSITEiView protein in PROSITE
PS01011. FOLYLPOLYGLU_SYNT_1. 1 hit.
PS01012. FOLYLPOLYGLU_SYNT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D5DT67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITTYEEALD WIHNRLRFGI KPGLERMEWM LEQLDFPQQN LNAIHVAGTN
60 70 80 90 100
GKGSTVSYLR NMLEEAGYKV GTFTSPYIET FNERISVNGK PISNEAMTAL
110 120 130 140 150
VQEIKPVVER LEHTNLGSAT EFEVITVMAF LYFGYHESVD YAVFETGLGG
160 170 180 190 200
RYDSTNVVNP MVSIITNIGF DHMAILGDTV EEIAAEKAGI IKKEVPIITG
210 220 230 240 250
AEQVKALDVI TEEAKSKQAS LFVLGKDFDI KNYEPLANGE GFALKMPYGT
260 270 280 290 300
FEHLELNMLG YHQVKNAALA VMAVCYLKEK KKLSISKEQM IKGIQHTKWN
310 320 330 340 350
GRFEIVNEHP LTIIDGAHNA EGIDSLLSTL RLHYEDRSIH LVFSCLNDKS
360 370 380 390 400
ADRMVQELET IAASITFTSF DFPRARPAQE LYEMSTHHNK HMDEEWKKAI
410 420 430
AYVKEKATGE QDMVVITGSL YFISEVRAFL LK
Length:432
Mass (Da):48,734
Last modified:June 15, 2010 - v1
Checksum:i2A966621DEA6C7F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001983 Genomic DNA. Translation: ADE71679.1.
RefSeqiWP_013059352.1. NC_014019.1.

Genome annotation databases

EnsemblBacteriaiADE71679; ADE71679; BMQ_4676.
KEGGibmq:BMQ_4676.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD5DT67_BACMQ
AccessioniPrimary (citable) accession number: D5DT67
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: June 7, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported