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Protein

Glutamate decarboxylase

Gene

BMQ_2467

Organism
Bacillus megaterium (strain ATCC 12872 / QMB1551)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBMEG545693:GHSY-2467-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:BMQ_2467Imported
OrganismiBacillus megaterium (strain ATCC 12872 / QMB1551)Imported
Taxonomic identifieri545693 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000000935 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei279 – 2791N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi545693.BMQ_2467.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiYTGRLFT.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

D5DSQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQWHPHREQ KNLPDEFPVN PLFSRQGEVT IPRLRIGDQG MLPETAYQII
60 70 80 90 100
HDEIALDGNA RLNLATFVTT WMEPDAKRLY GESFDKNMID KDEYPQTAAI
110 120 130 140 150
EERCVRILAD LWNSPNPDTT MGVSTTGSSE ACMLGGLALK RRWQKLRKSK
160 170 180 190 200
GLSTDRPNIV FSSSVQVVWE KFANYWDVEP RYVNINPDHP YLDAEGVINA
210 220 230 240 250
VDENTIGVVP ILGVTYTGVY EPIAAIAKAL DELQEKTGLD IPIHVDAASG
260 270 280 290 300
GFIAPFLQPD LIWDFRLPRV KSINVSGHKY GLVYPGLGWV IWREKEDLPE
310 320 330 340 350
DLIFRVSYLG GNMPTFALNF SRPGAQVLLQ YYNFLRLGKD GYYAVQKTSQ
360 370 380 390 400
ENALFLSKEI GEMDAFEILA DGSDIPVLAW KLKEDYTPNW TLYDLSRQLR
410 420 430 440 450
TYGWQVPAYP LPADMEEITI MRIVVRNGFS RDLAHLFMVN FKQAVEFLNS
460
LDRPVLKDTK YDNGFHH
Length:467
Mass (Da):53,195
Last modified:June 15, 2010 - v1
Checksum:iA89983593B08F004
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001983 Genomic DNA. Translation: ADE69489.1.
RefSeqiWP_013057164.1. NC_014019.1.

Genome annotation databases

EnsemblBacteriaiADE69489; ADE69489; BMQ_2467.
KEGGibmq:BMQ_2467.
PATRICi35481656. VBIBacMeg35839_2498.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001983 Genomic DNA. Translation: ADE69489.1.
RefSeqiWP_013057164.1. NC_014019.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi545693.BMQ_2467.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADE69489; ADE69489; BMQ_2467.
KEGGibmq:BMQ_2467.
PATRICi35481656. VBIBacMeg35839_2498.

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiYTGRLFT.
OrthoDBiPOG091H06F5.

Enzyme and pathway databases

BioCyciBMEG545693:GHSY-2467-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD5DSQ6_BACMQ
AccessioniPrimary (citable) accession number: D5DSQ6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 7, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.