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D5DB23 (D5DB23_BACMD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:BMD_0812 EMBL ADF37674.1
OrganismBacillus megaterium (strain DSM 319) [Complete proteome] [HAMAP] EMBL ADF37674.1
Taxonomic identifier592022 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length922 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS021135

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1521 By similarity HAMAP-Rule MF_00595
Active site5791 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
D5DB23 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: E41A4A8FAF278B70

FASTA922105,986
        10         20         30         40         50         60 
MVTVEAAERQ NSSTALRRDV KFLGQLLGKV LVHQGGEELL SKVEKIREVA KSLRENKDEV 

        70         80         90        100        110        120 
IYKEIKNEIV TLEQPMREQV IRAFAVYFHL VNIAEQNHRI RRRREYQQQE DSIMQPGSLE 

       130        140        150        160        170        180 
SAVVSLKNNG VAPDVIANLL QTLSLELIIT AHPTEATRRS VLDIHKRMAE LLKNLDNPTL 

       190        200        210        220        230        240 
TKRERTEIEE RLFSEVLILW QTNELRDRKP TVMDEVSNGL YYFDETLFEV LPQLHQELEN 

       250        260        270        280        290        300 
SLQENYPEEN WKVPNILRFG SWIGGDRDGN PNVTPKVTWQ TLVKQRKLAI RKYKESLTQL 

       310        320        330        340        350        360 
RQRLSQSTKR VAVSDNLLDS INQEISLLPE KKRWRIKHEV YRCKLTIMLH KLNLVGESEA 

       370        380        390        400        410        420 
GYQRSEELLH DLFLIKDSLQ KHQPQDYQLK SLCKLIRQVE LFGFHLATLD IRNHSGEHEA 

       430        440        450        460        470        480 
AIKEIFHAVS LAEDYSALTE EKKVELLGKV LQDPRPVISF VENYSKETQQ VIEVFNMIHR 

       490        500        510        520        530        540 
AHKEFGERSI EVYLISMTQS ASDLLEVMVL AKEAGIYRLH ADGRIESKLN IAPLLETIDD 

       550        560        570        580        590        600 
LTAGPKIMEQ LFQLDFYREH LREQQDLQEI MLGYSDGSKD GGTLTANWKL YKAQQEIHDM 

       610        620        630        640        650        660 
AKKYQVRLKF FHGRGGSLGR GGGPLNRSIL SQPVETLGDG VKITEQGEVL SSRYALYDIA 

       670        680        690        700        710        720 
YRSLEQAVSA LLTAAANVSQ EAEQCDIRTH EWEETMDEIS TASLRKYQEL VFKDPDFLTY 

       730        740        750        760        770        780 
FKQATPLPEL GALNIGSRPM SRKGSDRFED LRAIPWVFAW TQSRQLLPAW YAAGTGLQHL 

       790        800        810        820        830        840 
VEKSGDIQLL QQMYKEWPFF RSTVDNLQMA LTKADLMAAK EYTEMVQDPA ISERIFTAIK 

       850        860        870        880        890        900 
KEYNLTKEMI LQITGQKELM DHLPTIKESI KLRNPYVDPL TFLQVKVISK LREDEAGTLN 

       910        920 
EELLKEALLT INGIAAGLRN TG 

« Hide

References

[1]"Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 319.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001982 Genomic DNA. Translation: ADF37674.1.
RefSeqYP_003596024.1. NC_014103.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADF37674; ADF37674; BMD_0812.
GeneID9116203.
KEGGbmd:BMD_0812.
PATRIC37251605. VBIBacMeg104484_0729.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.

Enzyme and pathway databases

BioCycBMEG592022:GIVX-812-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5DB23_BACMD
AccessionPrimary (citable) accession number: D5DB23
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)