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D5DB23

- D5DB23_BACMD

UniProt

D5DB23 - D5DB23_BACMD

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Bacillus megaterium (strain DSM 319)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei152 – 1521UniRule annotation
Active sitei579 – 5791UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBMEG592022:GIVX-812-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:BMD_0812Imported
OrganismiBacillus megaterium (strain DSM 319)Imported
Taxonomic identifieri592022 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000002365: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiIDIVAQK.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5DB23-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVTVEAAERQ NSSTALRRDV KFLGQLLGKV LVHQGGEELL SKVEKIREVA
60 70 80 90 100
KSLRENKDEV IYKEIKNEIV TLEQPMREQV IRAFAVYFHL VNIAEQNHRI
110 120 130 140 150
RRRREYQQQE DSIMQPGSLE SAVVSLKNNG VAPDVIANLL QTLSLELIIT
160 170 180 190 200
AHPTEATRRS VLDIHKRMAE LLKNLDNPTL TKRERTEIEE RLFSEVLILW
210 220 230 240 250
QTNELRDRKP TVMDEVSNGL YYFDETLFEV LPQLHQELEN SLQENYPEEN
260 270 280 290 300
WKVPNILRFG SWIGGDRDGN PNVTPKVTWQ TLVKQRKLAI RKYKESLTQL
310 320 330 340 350
RQRLSQSTKR VAVSDNLLDS INQEISLLPE KKRWRIKHEV YRCKLTIMLH
360 370 380 390 400
KLNLVGESEA GYQRSEELLH DLFLIKDSLQ KHQPQDYQLK SLCKLIRQVE
410 420 430 440 450
LFGFHLATLD IRNHSGEHEA AIKEIFHAVS LAEDYSALTE EKKVELLGKV
460 470 480 490 500
LQDPRPVISF VENYSKETQQ VIEVFNMIHR AHKEFGERSI EVYLISMTQS
510 520 530 540 550
ASDLLEVMVL AKEAGIYRLH ADGRIESKLN IAPLLETIDD LTAGPKIMEQ
560 570 580 590 600
LFQLDFYREH LREQQDLQEI MLGYSDGSKD GGTLTANWKL YKAQQEIHDM
610 620 630 640 650
AKKYQVRLKF FHGRGGSLGR GGGPLNRSIL SQPVETLGDG VKITEQGEVL
660 670 680 690 700
SSRYALYDIA YRSLEQAVSA LLTAAANVSQ EAEQCDIRTH EWEETMDEIS
710 720 730 740 750
TASLRKYQEL VFKDPDFLTY FKQATPLPEL GALNIGSRPM SRKGSDRFED
760 770 780 790 800
LRAIPWVFAW TQSRQLLPAW YAAGTGLQHL VEKSGDIQLL QQMYKEWPFF
810 820 830 840 850
RSTVDNLQMA LTKADLMAAK EYTEMVQDPA ISERIFTAIK KEYNLTKEMI
860 870 880 890 900
LQITGQKELM DHLPTIKESI KLRNPYVDPL TFLQVKVISK LREDEAGTLN
910 920
EELLKEALLT INGIAAGLRN TG
Length:922
Mass (Da):105,986
Last modified:June 15, 2010 - v1
Checksum:iE41A4A8FAF278B70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001982 Genomic DNA. Translation: ADF37674.1.
RefSeqiYP_003596024.1. NC_014103.1.

Genome annotation databases

EnsemblBacteriaiADF37674; ADF37674; BMD_0812.
GeneIDi9116203.
KEGGibmd:BMD_0812.
PATRICi37251605. VBIBacMeg104484_0729.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001982 Genomic DNA. Translation: ADF37674.1 .
RefSeqi YP_003596024.1. NC_014103.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADF37674 ; ADF37674 ; BMD_0812 .
GeneIDi 9116203.
KEGGi bmd:BMD_0812.
PATRICi 37251605. VBIBacMeg104484_0729.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi IDIVAQK.

Enzyme and pathway databases

BioCyci BMEG592022:GIVX-812-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
    Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 319Imported.

Entry informationi

Entry nameiD5DB23_BACMD
AccessioniPrimary (citable) accession number: D5DB23
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 26, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3