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D5DAJ0 (D5DAJ0_BACMD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tryptophan--tRNA ligase HAMAP-Rule MF_00140
EC=6.1.1.2 HAMAP-Rule MF_00140
Alternative name(s):
Tryptophanyl-tRNA synthetase HAMAP-Rule MF_00140
Gene names
Name:trpS HAMAP-Rule MF_00140 EMBL ADF37569.1
Ordered Locus Names:BMD_0705 EMBL ADF37569.1
OrganismBacillus megaterium (strain DSM 319) [Complete proteome] [HAMAP] EMBL ADF37569.1
Taxonomic identifier592022 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp). SAAS SAAS024109 HAMAP-Rule MF_00140

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00140

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00140.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489 HAMAP-Rule MF_00140

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif10 – 189"HIGH" region By similarity HAMAP-Rule MF_00140
Motif192 – 1965"KMSKS" region By similarity HAMAP-Rule MF_00140

Sites

Binding site1951ATP By similarity HAMAP-Rule MF_00140

Sequences

Sequence LengthMass (Da)Tools
D5DAJ0 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: FD78423C2D9A2F69

FASTA32836,501
        10         20         30         40         50         60 
MKTIFSGIQP SGTITLGNYI GAMKQFVELQ HDYNCHFCIV DQHAITAPQD RLALRKNIRS 

        70         80         90        100        110        120 
LAALYVAVGI DPAKSTLFIQ SEVPAHTEAG WMLQCVAYIG ELERMTQFKD KSAGKEAVSA 

       130        140        150        160        170        180 
GLLTYPPLMA ADILLYNTDL VPVGEDQKQH LELTRDLAER FNKKYNDIFT IPEVRIPKVG 

       190        200        210        220        230        240 
ARVMSLQDPT KKMSKSDPNQ KAFITLLDDA KTIEKKIKSA VTDSEGIVRY DKENKPGISN 

       250        260        270        280        290        300 
LLSIYSILAN KSIEDIEAMY EGKGYGDFKA DTAKVVAEAL APIQERYYEL VDSSELDDIL 

       310        320 
DQGADKANAT ANKMLRKMRN AMGIGRKR

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References

[1]"Genome sequences of the industrial vitamin B12-producers B. megaterium QM B1551 and DSM319 reveal new insights into the Bacillus genome evolution and pan-genome structure."
Eppinger M., Bunk B., Johns M.A., Edirisinghe J.N., Kutumbaka K.K., Riley D.R., Creasy H.H., Koenig S.S.K., Galens K., Orvis J., Creasy T., Biedendieck R., Braun C., Grayburn S., Jahn D., Ravel J., Vary P.S.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 319.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001982 Genomic DNA. Translation: ADF37569.1.
RefSeqYP_003595919.1. NC_014103.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADF37569; ADF37569; BMD_0705.
GeneID9116096.
KEGGbmd:BMD_0705.
PATRIC37251379. VBIBacMeg104484_0617.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000059940.
KOK01867.

Enzyme and pathway databases

BioCycBMEG592022:GIVX-705-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00140_B. Trp_tRNA_synth_B.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERPTHR10055. PTHR10055. 1 hit.
PfamPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSPR01039. TRNASYNTHTRP.
TIGRFAMsTIGR00233. trpS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5DAJ0_BACMD
AccessionPrimary (citable) accession number: D5DAJ0
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info