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Protein

Superoxide dismutase

Gene

sodA

Organism
Escherichia coli O18:K1:H7 (strain IHE3034 / ExPEC)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciECOL714962:GI9T-4374-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodAImported
Ordered Locus Names:ECOK1_4376Imported
OrganismiEscherichia coli O18:K1:H7 (strain IHE3034 / ExPEC)Imported
Taxonomic identifieri714962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000002364 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000013583.
KOiK04564.
OMAiKHHNAYT.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5D5W7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYTLPSLPY AYDALEPHFD KQTMEIHHTK HHQAYVNNAN AALESLPEFA
60 70 80 90 100
NLPVEELITK LDQLPADKKT VLRNNAGGHA NHSLFWKGLK KGTTLQGDLK
110 120 130 140 150
AAIERDFGSV DNFKAEFEKA AASRFGSGWA WLVQKGDKLA VVSTANQDSP
160 170 180 190 200
LMGEAISGAS GFPILGLDVW EHAYYLKFQN RRPDYIKEFW NVVNWDEAAA

RFAAKK
Length:206
Mass (Da):23,064
Last modified:June 15, 2010 - v1
Checksum:iE7057DB9C7BFB4C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001969 Genomic DNA. Translation: ADE91459.1.
RefSeqiYP_006103452.1. NC_017628.1.

Genome annotation databases

EnsemblBacteriaiADE91459; ADE91459; ECOK1_4376.
KEGGieih:ECOK1_4376.
PATRICi36710285. VBIEscCol148715_4408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001969 Genomic DNA. Translation: ADE91459.1.
RefSeqiYP_006103452.1. NC_017628.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADE91459; ADE91459; ECOK1_4376.
KEGGieih:ECOK1_4376.
PATRICi36710285. VBIEscCol148715_4408.

Phylogenomic databases

HOGENOMiHOG000013583.
KOiK04564.
OMAiKHHNAYT.

Enzyme and pathway databases

BioCyciECOL714962:GI9T-4374-MONOMER.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IHE3034 / ExPECImported.
  2. "Identification of protective and broadly conserved vaccine antigens from the genome of Extraintestinal Pathogenic Escherichia coli (ExPEC)."
    Moriel D.G., Bertoldi I., Spagnuolo A., Marchi S., Rosini R., Nesta B., Pastorello I., Mariani Corea V.A., Torricelli G., Cartocci E., Savino S., Scarselli M., Dobrindt U., Hacker J., Tettelin H., Wieler L.H., Ewers C., Picard D.
    , Dougan G., Fontana M.R., Rappuoli R., Pizza M., Serino L.
    Proc. Natl. Acad. Sci. U.S.A. 0:0-0(2010)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IHE3034.

Entry informationi

Entry nameiD5D5W7_ECOKI
AccessioniPrimary (citable) accession number: D5D5W7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: April 1, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.