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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Sideroxydans lithotrophicus (strain ES-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei152UniRule annotation1
Active sitei583UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSLIT580332:G1GHN-264-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Slit_0266Imported
OrganismiSideroxydans lithotrophicus (strain ES-1)Imported
Taxonomic identifieri580332 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesGallionellaceaeSideroxydans
Proteomesi
  • UP000001625 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi580332.Slit_0266

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D5CLC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLISAPADI SSKDIPLRDD VRLLGRILGD TLREQEGEET YKLIESVRRA
60 70 80 90 100
AVRFRKTQDE QDGELLEQML DQLSPTETLV VVRAFSYFSQ LTNIAEDLHH
110 120 130 140 150
NRRHRAHLKA GSPPKDGTLQ LALDRLEEKK IDKDTLQSFL NSALVSPVLT
160 170 180 190 200
AHPTEVQRKS ILDCHLIISS LLANRDRVDM TPDDLAENEE ALHRFVLILW
210 220 230 240 250
QTRMMRTAKL NVRDEIRNGL EYYHYTFLAE IPKLYANLEK QLESRFDKDI
260 270 280 290 300
KVPPLLRVGS WIGGDRDGNP FVTHDVMTDA VREHSILALE YYLNETHLLG
310 320 330 340 350
TRLSLTDRLV EVTPELRKLS DASPDNVFVR LDEPYRRALI LIYSRLTATA
360 370 380 390 400
KHLGHDTSHL RPVDAHAQPY ATAQDFIADL DVMIDSLFKH GAVYLARGRL
410 420 430 440 450
ANLRRAVEVF GFYLAPLDMR QHSAILEQTV SELFSHSSGK ANYSDLDEAG
460 470 480 490 500
KRSVLLEALQ SGKILLADIK RYSDVPQSEL RIMQAAAEIH RRFGHGALPN
510 520 530 540 550
HIISKTDAVS DMLEVALMLQ QFGLLQDGDT LHVNIIPLFE TIEDLRGGAS
560 570 580 590 600
IMDELFSIPW YRKLLSSRGN TQEVMLGYSD SNKDGGYLTA NWELYKAEVE
610 620 630 640 650
LVKVFAKHGI ELRLFHGRGG TVGRGGGPSY DAILAQPPGS VNGQIRITEQ
660 670 680 690 700
GEVISSKYSN PEIGRRNLET LIAATIEATL LDHPHNADGD PEYMRIMEAL
710 720 730 740 750
SLDAFAAYRK LVYETPGFTD YFFTATPIRE IAELNIGSRP SSRKASDRIE
760 770 780 790 800
DLRAIPWVFS WGLNRVMLPG WFGFGSAVKQ FIQREGDAGL KQLQAMYKNW
810 820 830 840 850
AFFRGMMSNM DMVLSKSDMG IAWRYAELVQ DIELRDRIFG AINNEWEATI
860 870 880 890 900
EMLFAVTGAT TLLQDNPAFA RSLLTRTPYI DPLNHLQVAL LHRHRAGDND
910 920
EKVKRAIHLT INGIATGLRN SG
Length:922
Mass (Da):104,068
Last modified:June 15, 2010 - v1
Checksum:i2545BADBFFF9018B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001965 Genomic DNA Translation: ADE10508.1
RefSeqiWP_013028407.1, NC_013959.1

Genome annotation databases

EnsemblBacteriaiADE10508; ADE10508; Slit_0266
KEGGislt:Slit_0266

Similar proteinsi

Entry informationi

Entry nameiD5CLC0_SIDLE
AccessioniPrimary (citable) accession number: D5CLC0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: March 28, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health