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D5CBH1

- D5CBH1_ENTCC

UniProt

D5CBH1 - D5CBH1_ENTCC

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Protein

Xylose isomerase

Gene
xylA, ECL_00201
Organism
Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei122 – 1221 By similarityUniRule annotation
Active sitei125 – 1251 By similarityUniRule annotation
Metal bindingi253 – 2531Magnesium 1 By similarityUniRule annotation
Metal bindingi289 – 2891Magnesium 1 By similarityUniRule annotation
Metal bindingi289 – 2891Magnesium 2 By similarityUniRule annotation
Metal bindingi292 – 2921Magnesium 2 By similarityUniRule annotation
Metal bindingi317 – 3171Magnesium 1 By similarityUniRule annotation
Metal bindingi328 – 3281Magnesium 2 By similarityUniRule annotation
Metal bindingi330 – 3301Magnesium 2 By similarityUniRule annotation
Metal bindingi360 – 3601Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciECLO716541:GH13-202-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:ECL_00201Imported
OrganismiEnterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56)Imported
Taxonomic identifieri716541 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
ProteomesiUP000002363: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliD5CBH1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000252293.
KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5CBH1-1 [UniParc]FASTAAdd to Basket

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MSIHYYSCIN DSPHTLIMEL NMQAYFDQLD RVRYEGPKTT NPLAFRHYNP    50
DELVLGKRME DHLRFAACYW HTFCWNGADM FGVGSFDRPW QQPGEAIELA 100
KRKADVAFEF FHKLNVPYYC FHDVDVSPEG ASLKEYLNNF AQMVDVLAAK 150
QQQSGVKLLW GTANCFTNPR YGAGAATNPD PEVFSWAATQ VVTAMNATHQ 200
LGGENYVLWG GREGYETLLN TDLRQEREQI GRFMQMVVEH KHKIGFRGTL 250
LIEPKPQEPT KHQYDYDVAT VYGFLKQFGL EKEIKVNIEA NHATLAGHSF 300
HHEIASAIAL GIFGSVDANR GDAQLGWDTD QFPNSVEENA LVMYEIIKAG 350
GFTTGGLNFD AKVRRQSTDK YDLFYGHIGA MDTMALALKV AARMIEDGEL 400
DKRVAKRYSG WNSELGQQIL KGQLSLAEIA KYAEQHQLAP QHQSGHQELL 450
ENLVNHYLFD K 461
Length:461
Mass (Da):52,261
Last modified:June 15, 2010 - v1
Checksum:iBFD58C9651FA53E3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001918 Genomic DNA. Translation: ADF59769.1.
RefSeqiWP_013094964.1. NC_014121.1.
YP_003610718.1. NC_014121.1.

Genome annotation databases

EnsemblBacteriaiADF59769; ADF59769; ECL_00201.
GeneIDi9122712.
KEGGienc:ECL_00201.
PATRICi38451431. VBIEntClo148801_0494.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001918 Genomic DNA. Translation: ADF59769.1 .
RefSeqi WP_013094964.1. NC_014121.1.
YP_003610718.1. NC_014121.1.

3D structure databases

ProteinModelPortali D5CBH1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADF59769 ; ADF59769 ; ECL_00201 .
GeneIDi 9122712.
KEGGi enc:ECL_00201.
PATRICi 38451431. VBIEntClo148801_0494.

Phylogenomic databases

HOGENOMi HOG000252293.
KOi K01805.

Enzyme and pathway databases

BioCyci ECLO716541:GH13-202-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Enterobacter cloacae subsp. cloacae type strain ATCC 13047."
    Ren Y., Ren Y., Zhou Z., Guo X., Li Y., Feng L., Wang L.
    J. Bacteriol. 192:2463-2464(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56.

Entry informationi

Entry nameiD5CBH1_ENTCC
AccessioniPrimary (citable) accession number: D5CBH1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 3, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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