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D5CBH1

- D5CBH1_ENTCC

UniProt

D5CBH1 - D5CBH1_ENTCC

Protein

Xylose isomerase

Gene

xylA

Organism
Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (15 Jun 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei122 – 1221UniRule annotation
    Active sitei125 – 1251UniRule annotation
    Metal bindingi253 – 2531Magnesium 1UniRule annotation
    Metal bindingi289 – 2891Magnesium 1UniRule annotation
    Metal bindingi289 – 2891Magnesium 2UniRule annotation
    Metal bindingi292 – 2921Magnesium 2UniRule annotation
    Metal bindingi317 – 3171Magnesium 1UniRule annotation
    Metal bindingi328 – 3281Magnesium 2UniRule annotation
    Metal bindingi330 – 3301Magnesium 2UniRule annotation
    Metal bindingi360 – 3601Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciECLO716541:GH13-202-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    Ordered Locus Names:ECL_00201Imported
    OrganismiEnterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56)Imported
    Taxonomic identifieri716541 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEnterobacterEnterobacter cloacae complex
    ProteomesiUP000002363: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD5CBH1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000252293.
    KOiK01805.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D5CBH1-1 [UniParc]FASTAAdd to Basket

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    MSIHYYSCIN DSPHTLIMEL NMQAYFDQLD RVRYEGPKTT NPLAFRHYNP    50
    DELVLGKRME DHLRFAACYW HTFCWNGADM FGVGSFDRPW QQPGEAIELA 100
    KRKADVAFEF FHKLNVPYYC FHDVDVSPEG ASLKEYLNNF AQMVDVLAAK 150
    QQQSGVKLLW GTANCFTNPR YGAGAATNPD PEVFSWAATQ VVTAMNATHQ 200
    LGGENYVLWG GREGYETLLN TDLRQEREQI GRFMQMVVEH KHKIGFRGTL 250
    LIEPKPQEPT KHQYDYDVAT VYGFLKQFGL EKEIKVNIEA NHATLAGHSF 300
    HHEIASAIAL GIFGSVDANR GDAQLGWDTD QFPNSVEENA LVMYEIIKAG 350
    GFTTGGLNFD AKVRRQSTDK YDLFYGHIGA MDTMALALKV AARMIEDGEL 400
    DKRVAKRYSG WNSELGQQIL KGQLSLAEIA KYAEQHQLAP QHQSGHQELL 450
    ENLVNHYLFD K 461
    Length:461
    Mass (Da):52,261
    Last modified:June 15, 2010 - v1
    Checksum:iBFD58C9651FA53E3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001918 Genomic DNA. Translation: ADF59769.1.
    RefSeqiWP_013094964.1. NC_014121.1.
    YP_003610718.1. NC_014121.1.

    Genome annotation databases

    EnsemblBacteriaiADF59769; ADF59769; ECL_00201.
    GeneIDi9122712.
    KEGGienc:ECL_00201.
    PATRICi38451431. VBIEntClo148801_0494.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001918 Genomic DNA. Translation: ADF59769.1 .
    RefSeqi WP_013094964.1. NC_014121.1.
    YP_003610718.1. NC_014121.1.

    3D structure databases

    ProteinModelPortali D5CBH1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADF59769 ; ADF59769 ; ECL_00201 .
    GeneIDi 9122712.
    KEGGi enc:ECL_00201.
    PATRICi 38451431. VBIEntClo148801_0494.

    Phylogenomic databases

    HOGENOMi HOG000252293.
    KOi K01805.

    Enzyme and pathway databases

    BioCyci ECLO716541:GH13-202-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Enterobacter cloacae subsp. cloacae type strain ATCC 13047."
      Ren Y., Ren Y., Zhou Z., Guo X., Li Y., Feng L., Wang L.
      J. Bacteriol. 192:2463-2464(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56Imported.

    Entry informationi

    Entry nameiD5CBH1_ENTCC
    AccessioniPrimary (citable) accession number: D5CBH1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3