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D5C6R3 (D5C6R3_ENTCC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length1022 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. SAAS SAAS013812 HAMAP-Rule MF_01687

Cofactor

Binds 1 sodium ion per monomer By similarity. HAMAP-Rule MF_01687

Binds 2 magnesium ions per monomer By similarity. HAMAP-Rule MF_01687

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01687

Sequence similarities

Belongs to the glycosyl hydrolase 2 family. HAMAP-Rule MF_01687

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region536 – 5394Substrate binding By similarity HAMAP-Rule MF_01687

Sites

Active site4601Proton donor By similarity HAMAP-Rule MF_01687
Active site5361Nucleophile By similarity HAMAP-Rule MF_01687
Metal binding2001Sodium By similarity HAMAP-Rule MF_01687
Metal binding4151Magnesium 1 By similarity HAMAP-Rule MF_01687
Metal binding4171Magnesium 1 By similarity HAMAP-Rule MF_01687
Metal binding4601Magnesium 1 By similarity HAMAP-Rule MF_01687
Metal binding5961Magnesium 2 By similarity HAMAP-Rule MF_01687
Metal binding6001Sodium; via carbonyl oxygen By similarity HAMAP-Rule MF_01687
Metal binding6031Sodium By similarity HAMAP-Rule MF_01687
Binding site1011Substrate By similarity HAMAP-Rule MF_01687
Binding site2001Substrate By similarity HAMAP-Rule MF_01687
Binding site4601Substrate By similarity HAMAP-Rule MF_01687
Binding site6031Substrate By similarity HAMAP-Rule MF_01687
Binding site9981Substrate By similarity HAMAP-Rule MF_01687
Site3561Transition state stabilizer By similarity HAMAP-Rule MF_01687
Site3901Transition state stabilizer By similarity HAMAP-Rule MF_01687

Sequences

Sequence LengthMass (Da)Tools
D5C6R3 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 1B8314BA008F69EF

FASTA1,022116,183
        10         20         30         40         50         60 
MITDSLAVVL QRRDWENPGV TQLNRLAAHP PFASWRNSEE ARTDRPSQES RSLNGEWRFA 

        70         80         90        100        110        120 
WFPAPEAVPE SWLERDLPDA DTVIVPSNWQ MHGYDAPIYT NVTYPIAVNP PYVPTENPTG 

       130        140        150        160        170        180 
CYSLTFNVDE SWLQEGQTRI IFDGVNSAFH LWCNGRWVGY GQDSRLPSEF DLSAFLHAGE 

       190        200        210        220        230        240 
NRLAVMVLRW SDGSYLEDQD MWRMSGIFRD VSLLHKPSTQ ISDFHVATHF NDDFSRAVLE 

       250        260        270        280        290        300 
ADVQMYGELR DELRVTVSLW QGETQVASGT APFGGEIIDE RGGYADHVTL RLNVENPKLW 

       310        320        330        340        350        360 
SAEIPNLYRA VVELHTADGT LIEAEACDVG FREVRIENGL LLLNGKPLLI RGVNRHEHHP 

       370        380        390        400        410        420 
LHGQVMDEQT MVQDILLMKQ NNFNAVRCSH YPNHPLWYTL CDHYGLYVVD EANIETHGMV 

       430        440        450        460        470        480 
PMNRLTDDPR WLPAMSERVT RMVQRDRNHP SVIIWSLGNE SGHGANHDAL YRWIKSVDPS 

       490        500        510        520        530        540 
RPVQYEGGGA DTFATDIICP MYARVDEDQP FPAVPKWSIK KWLSLPGETR PLILCEYAHA 

       550        560        570        580        590        600 
MGNSLGGFAK YWQAFRQYPR LQGGFVWDWV DQSLIKYDEN GNPWSAYGGD FGDKPNDRQF 

       610        620        630        640        650        660 
CMNGLVFADR TPHPALTEAK HQQQFFQFSL SGRTIEVTSE YLFRHSDNEL LHWMVALDGK 

       670        680        690        700        710        720 
PLASGEVPLD VAPQGKQLIE LPELPQPKSA GQLWLTVHVV QPNATTWSAA GHISAWQQWR 

       730        740        750        760        770        780 
LAENLSVTLP SAPHAIPQLT TSETDFCIEL DNKRWQFNRQ SGFLSQMWIG DKKQLLTPLR 

       790        800        810        820        830        840 
DQFTRAPLDN DIGVSEATRI DPNAWVERWK AAGHYQAEAA LLQCTADTLA DAVLITTVHA 

       850        860        870        880        890        900 
WQHQGKTLFI SRKTYRIDGS GQMAITVDVE VASNTPHPAR IGLTCQLAQV AERVNWLGLG 

       910        920        930        940        950        960 
PQENYPDRLT AACFDRWDLP LSDMYTPYVF PSENGLRCGT RELNYGPHQW RGDFQFNISR 

       970        980        990       1000       1010       1020 
YSQQQLMETS HRHLLHAEEG TWLNIDGFHM GIGGDDSWSP SVSAEFHLSA GSYHYQLLWC 


QK

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References

[1]"Complete genome sequence of Enterobacter cloacae subsp. cloacae type strain ATCC 13047."
Ren Y., Ren Y., Zhou Z., Guo X., Li Y., Feng L., Wang L.
J. Bacteriol. 192:2463-2464(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001918 Genomic DNA. Translation: ADF63225.1.
RefSeqYP_003614174.1. NC_014121.1.

3D structure databases

ProteinModelPortalD5C6R3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADF63225; ADF63225; ECL_03691.
GeneID9126168.
KEGGenc:ECL_03691.
PATRIC38458276. VBIEntClo148801_3849.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000252443.
KOK01190.

Enzyme and pathway databases

BioCycECLO716541:GH13-3657-MONOMER.

Family and domain databases

Gene3D2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_01687. Beta_gal.
InterProIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023933. Glyco_hydro_2_beta_Galsidase.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSPR00132. GLHYDRLASE2.
SMARTSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMSSF49785. Gal_bind_like. 1 hit.
SSF74650. Gal_mut_like. 1 hit.
SSF49303. Glyco_hydro_2Ig. 2 hits.
SSF51445. Glyco_hydro_cat. 1 hit.
PROSITEPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5C6R3_ENTCC
AccessionPrimary (citable) accession number: D5C6R3
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info