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D5C581

- D5C581_NITHN

UniProt

D5C581 - D5C581_NITHN

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Nitrosococcus halophilus (strain Nc4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei170 – 1701UniRule annotation
Active sitei619 – 6191UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciNHAL472759:GHH2-2244-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Nhal_2213Imported
OrganismiNitrosococcus halophilus (strain Nc4)Imported
Taxonomic identifieri472759 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
ProteomesiUP000001844: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiGIQITIN.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5C581-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPMMKQIPE AKPAPIASVS PDQTKNATPW RDKELRARVK LFGNLLGQVI
60 70 80 90 100
QAQSREKVFA AVEALRKGYI NLRKKENPDK RIQLLRLISK LDVETLTQVV
110 120 130 140 150
RAFSIYFSLA NIAEEAYQHR QRQRRIDAGG PLWRGSFEET LQEVRNGGVG
160 170 180 190 200
PGQLQILLDS LAYIPVITAH PTEAKRRTVM EHLRKIFLTS KLLDEARLSQ
210 220 230 240 250
REEEALHRQL ERQIQVLWKT DEVRAHRPQV RDEIINGLFY FKVSLFQAVP
260 270 280 290 300
ETYRQLEEAI HKVYGDDLPE NTTIRVPSFL HFGSWIGGDR DGNPNVKPEI
310 320 330 340 350
TAMAVRLQMR MALRHYLERI GELMRILTHS IPLIQPSTAL MDSINQDLND
360 370 380 390 400
CPEALLGNPT RFSHEPYRRK LYLMRYRLLD NLRAVELHLK PESGLSPPSG
410 420 430 440 450
VGYPSEDEFL QDLYLIRDSL INHGDGNIAA GELQDLIRLV ESFGFYLLKL
460 470 480 490 500
DIRQESSCHT EAVAELVKQA GLHPAYLDLS ETERQQLLSE QLAREEGVPI
510 520 530 540 550
DREQLTPPTR ETLEIFDVMA QMRREVSPRV FGTYVISMTH AASHVLEVMF
560 570 580 590 600
LGHLAGLAKH QQGQWHCDLQ ISPLFETIED LEHIEPVMTA LLDDPSYQAL
610 620 630 640 650
LQASGNQQEV MIGYSDSCKD GGILASSWKL YEAQKKVTAL TGDRGVDCRI
660 670 680 690 700
FHGRGGTIGR GGGPTFDAIL SQPRGTVHGQ IKFTEQGEVL SSRYSNTETA
710 720 730 740 750
IYELDMGISG LIKASACLVQ PPQEEKRDYL GVMDFLAEAG ERAYRELTEE
760 770 780 790 800
TPGFQDYFYE ATPVNEIGLL NIGSRPSHRK KGDRSKASVR AIAWVFGWAQ
810 820 830 840 850
ARHTFPAWYG IGSALEQWRA GAPDRLAKLQ AMYQEWPYFR AMLSNIQMSL
860 870 880 890 900
AKAELRIAQQ YAELCLDPET GERIFAMLSA EYQRTVTQVL HIVGAHTLLE
910 920 930 940 950
ENPSLALSLR RRDPYLDPLN HIQLTLIQRT RDPLLTPVER QAWIDPLLRS
960
INAIAAGMRN TG
Length:962
Mass (Da):109,063
Last modified:June 15, 2010 - v1
Checksum:iD2E4C47AA3F2DC3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001798 Genomic DNA. Translation: ADE15304.1.
RefSeqiYP_003527691.1. NC_013960.1.

Genome annotation databases

EnsemblBacteriaiADE15304; ADE15304; Nhal_2213.
GeneIDi8917208.
KEGGinhl:Nhal_2213.
PATRICi35394416. VBINitHal115488_2335.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001798 Genomic DNA. Translation: ADE15304.1 .
RefSeqi YP_003527691.1. NC_013960.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE15304 ; ADE15304 ; Nhal_2213 .
GeneIDi 8917208.
KEGGi nhl:Nhal_2213.
PATRICi 35394416. VBINitHal115488_2335.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi GIQITIN.

Enzyme and pathway databases

BioCyci NHAL472759:GHH2-2244-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Nitrosococcus halophilus Nc4, a salt-adapted, aerobic obligate ammonia-oxidizing sulfur purple bacterium."
    US DOE Joint Genome Institute
    Campbell M.A., Malfatti S.A., Chain P.S.G., Heidelberg J.F., Ward B.B., Klotz M.G.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nc4Imported.

Entry informationi

Entry nameiD5C581_NITHN
AccessioniPrimary (citable) accession number: D5C581
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 26, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3