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D5BVY9

- D5BVY9_NITHN

UniProt

D5BVY9 - D5BVY9_NITHN

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Nitrosococcus halophilus (strain Nc4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei157 – 1571UniRule annotation
Active sitei591 – 5911UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciNHAL472759:GHH2-2519-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Nhal_2483Imported
OrganismiNitrosococcus halophilus (strain Nc4)Imported
Taxonomic identifieri472759 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesChromatiaceaeNitrosococcus
ProteomesiUP000001844: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiTIITHRE.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5BVY9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKHEYKLDIK AEESGLSEPL AKQLTLLGTL LEQAIRDQAG PKMLNLMGKL
60 70 80 90 100
HQLCGQVDTQ DNATLCEGAD TQIQKLSRDQ IVWLLHAYTS FFHLANQAEQ
110 120 130 140 150
QEIIRINWER VRQSRIDKPR PESIDEAIHH LQKQGYAREQ VLQLLGQLDI
160 170 180 190 200
QPTLTAHPTE ARRRSILFKQ QRISGLLAGL NQYSSTTPPE TERILDDLYN
210 220 230 240 250
QIALLLATDE VRAERPTVKQ EIHQGLYFMR IAIWEVAVQI YRDTQRALQQ
260 270 280 290 300
YYGEAPDFPP FLHYRSWIGG DRDGNPHVTP EITRWTIITH RETALRRYCT
310 320 330 340 350
ELQELYHELS LSERQVGIPP ALYRSLEQDA RETTLGHKFS EQLQREPYRL
360 370 380 390 400
KISYMMARLG KLLKPPNQTE TGENTYNSKR FIEDLQLLKR CLEESGFGKI
410 420 430 440 450
SRHGRLGRLL ILTQTFGFHL AALDVRQHSH IHEKAVAALL QIAGITRDYL
460 470 480 490 500
ALSEKERLAV LSAQLQKPHP LRVPNSVLPE STQQVLETFA VIRDAIAQEP
510 520 530 540 550
EAIGSYVISM THTISDLLEV MLLAKEAQLW QLQDGKVICP LDFVPLFETI
560 570 580 590 600
EALEAADKRM LALIKHPIYR QQIAARGHFQ EIMLGYSDSS KDGGYWMANW
610 620 630 640 650
ALHKAQKRLG KLCHQQKIDF RLFHGRGGTV GRGGGRTSQT AILAMPPAVH
660 670 680 690 700
NGRIRFTEQG EVISFRYALP AMARRHTEQI VNAMIQATAV AAQSGDKPSD
710 720 730 740 750
DSYHEDLMER IAQQAMGAYR TLIEQDGFWS WYTQVTPIEH ISHLPIASRP
760 770 780 790 800
ISRTSATEVD FKNLRAIPWV FAWTQTRYLV PGWFGLGQAL QKIMGDETLQ
810 820 830 840 850
ETLQKMYQQW PFFNTVIDDA QREMARARLK TASHYARLAN QNETRFHDII
860 870 880 890 900
VADFEKARKI ILEMSGQQEL LDNTPTIQKT IIFRNPYTDV LNLLQIELMK
910 920 930
RYRQAPENEK GLLRQALFLS LNGIAAAMQS TG
Length:932
Mass (Da):106,722
Last modified:June 15, 2010 - v1
Checksum:iD3175662C7E2BFD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001798 Genomic DNA. Translation: ADE15568.1.
RefSeqiWP_013033428.1. NC_013960.1.
YP_003527955.1. NC_013960.1.

Genome annotation databases

EnsemblBacteriaiADE15568; ADE15568; Nhal_2483.
GeneIDi8917483.
KEGGinhl:Nhal_2483.
PATRICi35394984. VBINitHal115488_2614.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001798 Genomic DNA. Translation: ADE15568.1 .
RefSeqi WP_013033428.1. NC_013960.1.
YP_003527955.1. NC_013960.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE15568 ; ADE15568 ; Nhal_2483 .
GeneIDi 8917483.
KEGGi nhl:Nhal_2483.
PATRICi 35394984. VBINitHal115488_2614.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi TIITHRE.

Enzyme and pathway databases

BioCyci NHAL472759:GHH2-2519-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Nitrosococcus halophilus Nc4, a salt-adapted, aerobic obligate ammonia-oxidizing sulfur purple bacterium."
    US DOE Joint Genome Institute
    Campbell M.A., Malfatti S.A., Chain P.S.G., Heidelberg J.F., Ward B.B., Klotz M.G.
    Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nc4Imported.

Entry informationi

Entry nameiD5BVY9_NITHN
AccessioniPrimary (citable) accession number: D5BVY9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: November 26, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3