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D5BPG8

- D5BPG8_PUNMI

UniProt

D5BPG8 - D5BPG8_PUNMI

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Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene
SAR116_0207
Organism
Puniceispirillum marinum (strain IMCC1322)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

Cofactori

Binds 1 lipoyl cofactor covalently By similarity.UniRule annotation
Binds 2 lipoyl cofactors covalently By similarity.UniRule annotation
Binds 3 lipoyl cofactors covalently By similarity.UniRule annotation

GO - Molecular functioni

  1. dihydrolipoyllysine-residue acetyltransferase activity Source: InterPro
  2. dihydrolipoyllysine-residue succinyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. pyruvate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BioCyciPMAR488538:GI1I-213-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
Gene namesi
Ordered Locus Names:SAR116_0207Imported
OrganismiPuniceispirillum marinum (strain IMCC1322)Imported
Taxonomic identifieri488538 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSAR116 clusterCandidatus Puniceispirillum
ProteomesiUP000007460: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. pyruvate dehydrogenase complex Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
Contains 1 lipoyl-binding domain.UniRule annotation

Keywords - Domaini

LipoylUniRule annotationSAAS annotations

Phylogenomic databases

HOGENOMiHOG000281566.
KOiK00627.
OMAiPISNIRK.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5BPG8-1 [UniParc]FASTAAdd to Basket

« Hide

MAIEIKMPAL SPTMEVGTLS KWMVAVGDDV RSGDVIAEIE TDKATMEVEA    50
VDDGKMAQIA VADGTENIPV GTVIALLAED GEDVATVSSA SPKPAASKLA 100
PPKEDAAGEE SGSAAKEAVA DDATKQEPAM DTSKPAPVSP RTSADTKRIF 150
ASPLARRIAA DKGVDLASLT GSGPHGRILR RDVEGAPASM QASLATTAPS 200
RAVTSSAEKG ASTLVPNNQM RKIIASRLQE SKQTAPHFYL TIDCNIDTLL 250
ESRKALNALA DEGIKISVND MVIRAAAMAL MKVPAANASW EGDNTRLFHN 300
ADICMAVAVD GGLVTPVIWA AESKGLSELS TISSDLATRA RDGKLAAEEF 350
TGGSFTISNL GMFGVREFAA VINPPQGAIL AVGAGEQRPV VIDGALSVAT 400
MMTVTLSCDH RAVDGAVGAE WLQAFKGFVE NPVTMLL 437
Length:437
Mass (Da):45,352
Last modified:June 15, 2010 - v1
Checksum:iC98F069881325B01
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001751 Genomic DNA. Translation: ADE38450.1.
RefSeqiYP_003550534.1. NC_014010.1.

Genome annotation databases

EnsemblBacteriaiADE38450; ADE38450; SAR116_0207.
GeneIDi8960528.
KEGGiapb:SAR116_0207.
PATRICi35447301. VBIAlpPro78664_0204.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001751 Genomic DNA. Translation: ADE38450.1 .
RefSeqi YP_003550534.1. NC_014010.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE38450 ; ADE38450 ; SAR116_0207 .
GeneIDi 8960528.
KEGGi apb:SAR116_0207.
PATRICi 35447301. VBIAlpPro78664_0204.

Phylogenomic databases

HOGENOMi HOG000281566.
KOi K00627.
OMAi PISNIRK.

Enzyme and pathway databases

BioCyci PMAR488538:GI1I-213-MONOMER.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of "Candidatus Puniceispirillum marinum" IMCC1322, a representative of the SAR116 clade in the Alphaproteobacteria."
    Oh H.M., Kwon K.K., Kang I., Kang S.G., Lee J.H., Kim S.J., Cho J.C.
    J. Bacteriol. 192:3240-3241(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMCC1322Imported.

Entry informationi

Entry nameiD5BPG8_PUNMI
AccessioniPrimary (citable) accession number: D5BPG8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 9, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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