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D5BPG8

- D5BPG8_PUNMI

UniProt

D5BPG8 - D5BPG8_PUNMI

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

SAR116_0207

Organism
Puniceispirillum marinum (strain IMCC1322)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (15 Jun 2010)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotationImported, Transferase

    Enzyme and pathway databases

    BioCyciPMAR488538:GI1I-213-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    Ordered Locus Names:SAR116_0207Imported
    OrganismiPuniceispirillum marinum (strain IMCC1322)Imported
    Taxonomic identifieri488538 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSAR116 clusterCandidatus Puniceispirillum
    ProteomesiUP000007460: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 lipoyl-binding domain.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotationSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000281566.
    KOiK00627.
    OMAiPISNIRK.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D5BPG8-1 [UniParc]FASTAAdd to Basket

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    MAIEIKMPAL SPTMEVGTLS KWMVAVGDDV RSGDVIAEIE TDKATMEVEA    50
    VDDGKMAQIA VADGTENIPV GTVIALLAED GEDVATVSSA SPKPAASKLA 100
    PPKEDAAGEE SGSAAKEAVA DDATKQEPAM DTSKPAPVSP RTSADTKRIF 150
    ASPLARRIAA DKGVDLASLT GSGPHGRILR RDVEGAPASM QASLATTAPS 200
    RAVTSSAEKG ASTLVPNNQM RKIIASRLQE SKQTAPHFYL TIDCNIDTLL 250
    ESRKALNALA DEGIKISVND MVIRAAAMAL MKVPAANASW EGDNTRLFHN 300
    ADICMAVAVD GGLVTPVIWA AESKGLSELS TISSDLATRA RDGKLAAEEF 350
    TGGSFTISNL GMFGVREFAA VINPPQGAIL AVGAGEQRPV VIDGALSVAT 400
    MMTVTLSCDH RAVDGAVGAE WLQAFKGFVE NPVTMLL 437
    Length:437
    Mass (Da):45,352
    Last modified:June 15, 2010 - v1
    Checksum:iC98F069881325B01
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001751 Genomic DNA. Translation: ADE38450.1.
    RefSeqiYP_003550534.1. NC_014010.1.

    Genome annotation databases

    EnsemblBacteriaiADE38450; ADE38450; SAR116_0207.
    GeneIDi8960528.
    KEGGiapb:SAR116_0207.
    PATRICi35447301. VBIAlpPro78664_0204.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001751 Genomic DNA. Translation: ADE38450.1 .
    RefSeqi YP_003550534.1. NC_014010.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADE38450 ; ADE38450 ; SAR116_0207 .
    GeneIDi 8960528.
    KEGGi apb:SAR116_0207.
    PATRICi 35447301. VBIAlpPro78664_0204.

    Phylogenomic databases

    HOGENOMi HOG000281566.
    KOi K00627.
    OMAi PISNIRK.

    Enzyme and pathway databases

    BioCyci PMAR488538:GI1I-213-MONOMER.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of "Candidatus Puniceispirillum marinum" IMCC1322, a representative of the SAR116 clade in the Alphaproteobacteria."
      Oh H.M., Kwon K.K., Kang I., Kang S.G., Lee J.H., Kim S.J., Cho J.C.
      J. Bacteriol. 192:3240-3241(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IMCC1322Imported.

    Entry informationi

    Entry nameiD5BPG8_PUNMI
    AccessioniPrimary (citable) accession number: D5BPG8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3