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D5BPG8 (D5BPG8_PUNMI) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyltransferase component of pyruvate dehydrogenase complex RuleBase RU361137

EC=2.3.1.12 RuleBase RU361137
Gene names
Ordered Locus Names:SAR116_0207 EMBL ADE38450.1
OrganismPuniceispirillum marinum (strain IMCC1322) [Complete proteome] [HAMAP] EMBL ADE38450.1
Taxonomic identifier488538 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSAR116 clusterCandidatus Puniceispirillum

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. RuleBase RU361137

Catalytic activity

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine. RuleBase RU361137

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. RuleBase RU361137

Binds 2 lipoyl cofactors covalently By similarity. RuleBase RU361137

Binds 3 lipoyl cofactors covalently By similarity. RuleBase RU361137

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU361137

Contains 1 lipoyl-binding domain. RuleBase RU361137

Sequences

Sequence LengthMass (Da)Tools
D5BPG8 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: C98F069881325B01

FASTA43745,352
        10         20         30         40         50         60 
MAIEIKMPAL SPTMEVGTLS KWMVAVGDDV RSGDVIAEIE TDKATMEVEA VDDGKMAQIA 

        70         80         90        100        110        120 
VADGTENIPV GTVIALLAED GEDVATVSSA SPKPAASKLA PPKEDAAGEE SGSAAKEAVA 

       130        140        150        160        170        180 
DDATKQEPAM DTSKPAPVSP RTSADTKRIF ASPLARRIAA DKGVDLASLT GSGPHGRILR 

       190        200        210        220        230        240 
RDVEGAPASM QASLATTAPS RAVTSSAEKG ASTLVPNNQM RKIIASRLQE SKQTAPHFYL 

       250        260        270        280        290        300 
TIDCNIDTLL ESRKALNALA DEGIKISVND MVIRAAAMAL MKVPAANASW EGDNTRLFHN 

       310        320        330        340        350        360 
ADICMAVAVD GGLVTPVIWA AESKGLSELS TISSDLATRA RDGKLAAEEF TGGSFTISNL 

       370        380        390        400        410        420 
GMFGVREFAA VINPPQGAIL AVGAGEQRPV VIDGALSVAT MMTVTLSCDH RAVDGAVGAE 

       430 
WLQAFKGFVE NPVTMLL 

« Hide

References

[1]"Complete genome sequence of "Candidatus Puniceispirillum marinum" IMCC1322, a representative of the SAR116 clade in the Alphaproteobacteria."
Oh H.M., Kwon K.K., Kang I., Kang S.G., Lee J.H., Kim S.J., Cho J.C.
J. Bacteriol. 192:3240-3241(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: IMCC1322 EMBL ADE38450.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001751 Genomic DNA. Translation: ADE38450.1.
RefSeqYP_003550534.1. NC_014010.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE38450; ADE38450; SAR116_0207.
GeneID8960528.
KEGGapb:SAR116_0207.
PATRIC35447301. VBIAlpPro78664_0204.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000281566.
KOK00627.
OMAPISNIRK.

Enzyme and pathway databases

BioCycPMAR488538:GI1I-213-MONOMER.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5BPG8_PUNMI
AccessionPrimary (citable) accession number: D5BPG8
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: July 9, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)