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D5BDP9 (RNC_ZUNPS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3
EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:ZPR_0280
OrganismZunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87) [Complete proteome] [HAMAP]
Taxonomic identifier655815 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Zunongwangia ›

Protein attributes

Sequence length243 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence caution

The sequence ADF50640.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 243243Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000416615

Regions

Domain19 – 144126RNase III
Domain172 – 24069DRBM

Sites

Active site651 Potential
Active site1331 By similarity
Metal binding611Magnesium By similarity
Metal binding1301Magnesium By similarity
Metal binding1331Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
D5BDP9 [UniParc].

Last modified April 18, 2012. Version 2.
Checksum: 04299BD2D6F4990E

FASTA24328,210
        10         20         30         40         50         60 
MSVIRNILNS RSSKGGNFFN TLHKLLGFRP KDLSVYERAF THRSLNVKDP SGNPINYERL 

        70         80         90        100        110        120 
EFLGDAMLGS VIASHLYQEV PEGDEGYLTK MRSKIVSRKH LNELGKDLNL IRFVKSNIPN 

       130        140        150        160        170        180 
DQFGVNIHGN IFEALVGAIY LDRGYKYCNR FIYNRVIEPY VDIETLEGRV ISYKSLLIEW 

       190        200        210        220        230        240 
CQKQKKEFNY QVYEDTGRDE LKHFAVKLWI DKKVIAKARA TSKKKAEEKA SKRAYYALQN 


KMN

« Hide

References

[1]"The complete genome of Zunongwangia profunda SM-A87 reveals its adaptation to the deep-sea environment and ecological role in sedimentary organic nitrogen degradation."
Qin Q.L., Zhang X.Y., Wang X.M., Liu G.M., Chen X.L., Xie B.B., Dang H.Y., Zhou B.C., Yu J., Zhang Y.Z.
BMC Genomics 11:247-247(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 18752 / CCTCC AB 206139 / SM-A87.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001650 Genomic DNA. Translation: ADF50640.1. Different initiation.
RefSeqYP_003582836.1. NC_014041.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADF50640; ADF50640; ZPR_0280.
GeneID9076156.
KEGGzpr:ZPR_0280.
PATRIC37230047. VBIZunPro130839_0270.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000246808.
KOK03685.

Enzyme and pathway databases

BioCycZPRO655815:GI6J-280-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_ZUNPS
AccessionPrimary (citable) accession number: D5BDP9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: April 18, 2012
Last modified: May 29, 2013
This is version 21 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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