SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D5BDP9

- RNC_ZUNPS

UniProt

D5BDP9 - RNC_ZUNPS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Ribonuclease 3
Gene
rnc, ZPR_0280
Organism
Zunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

Cofactori

Mg2+ By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611Magnesium By similarity
Active sitei65 – 651 Reviewed prediction
Metal bindingi130 – 1301Magnesium By similarity
Active sitei133 – 1331 By similarity
Metal bindingi133 – 1331Magnesium By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. rRNA binding Source: UniProtKB-KW
  3. ribonuclease III activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA processing Source: UniProtKB-HAMAP
  2. rRNA catabolic process Source: InterPro
  3. rRNA processing Source: UniProtKB-HAMAP
  4. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

mRNA processing, rRNA processing, tRNA processing

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciZPRO655815:GI6J-280-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 3 (EC:3.1.26.3)
Alternative name(s):
Ribonuclease III
Short name:
RNase III
Gene namesi
Name:rnc
Ordered Locus Names:ZPR_0280
OrganismiZunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87)
Taxonomic identifieri655815 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeZunongwangia
ProteomesiUP000001654: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 243243Ribonuclease 3UniRule annotation
PRO_0000416615Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 144126RNase III
Add
BLAST
Domaini172 – 24069DRBM
Add
BLAST

Sequence similaritiesi

Contains 1 RNase III domain.

Phylogenomic databases

HOGENOMiHOG000246808.
KOiK03685.

Family and domain databases

Gene3Di1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPiMF_00104. RNase_III.
InterProiIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERiPTHR11207. PTHR11207. 1 hit.
PfamiPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMiSSF69065. SSF69065. 1 hit.
TIGRFAMsiTIGR02191. RNaseIII. 1 hit.
PROSITEiPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D5BDP9-1 [UniParc]FASTAAdd to Basket

« Hide

MSVIRNILNS RSSKGGNFFN TLHKLLGFRP KDLSVYERAF THRSLNVKDP    50
SGNPINYERL EFLGDAMLGS VIASHLYQEV PEGDEGYLTK MRSKIVSRKH 100
LNELGKDLNL IRFVKSNIPN DQFGVNIHGN IFEALVGAIY LDRGYKYCNR 150
FIYNRVIEPY VDIETLEGRV ISYKSLLIEW CQKQKKEFNY QVYEDTGRDE 200
LKHFAVKLWI DKKVIAKARA TSKKKAEEKA SKRAYYALQN KMN 243
Length:243
Mass (Da):28,210
Last modified:April 18, 2012 - v2
Checksum:i04299BD2D6F4990E
GO

Sequence cautioni

The sequence ADF50640.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001650 Genomic DNA. Translation: ADF50640.1. Different initiation.
RefSeqiYP_003582836.1. NC_014041.1.

Genome annotation databases

EnsemblBacteriaiADF50640; ADF50640; ZPR_0280.
GeneIDi9076156.
KEGGizpr:ZPR_0280.
PATRICi37230047. VBIZunPro130839_0270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001650 Genomic DNA. Translation: ADF50640.1 . Different initiation.
RefSeqi YP_003582836.1. NC_014041.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADF50640 ; ADF50640 ; ZPR_0280 .
GeneIDi 9076156.
KEGGi zpr:ZPR_0280.
PATRICi 37230047. VBIZunPro130839_0270.

Phylogenomic databases

HOGENOMi HOG000246808.
KOi K03685.

Enzyme and pathway databases

BioCyci ZPRO655815:GI6J-280-MONOMER.

Family and domain databases

Gene3Di 1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPi MF_00104. RNase_III.
InterProi IPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view ]
PANTHERi PTHR11207. PTHR11207. 1 hit.
Pfami PF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view ]
SMARTi SM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view ]
SUPFAMi SSF69065. SSF69065. 1 hit.
TIGRFAMsi TIGR02191. RNaseIII. 1 hit.
PROSITEi PS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome of Zunongwangia profunda SM-A87 reveals its adaptation to the deep-sea environment and ecological role in sedimentary organic nitrogen degradation."
    Qin Q.L., Zhang X.Y., Wang X.M., Liu G.M., Chen X.L., Xie B.B., Dang H.Y., Zhou B.C., Yu J., Zhang Y.Z.
    BMC Genomics 11:247-247(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 18752 / CCTCC AB 206139 / SM-A87.

Entry informationi

Entry nameiRNC_ZUNPS
AccessioniPrimary (citable) accession number: D5BDP9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: April 18, 2012
Last modified: September 3, 2014
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi