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D5B377 (D5B377_YERPZ) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase HAMAP-Rule MF_00811
EC=2.3.1.117 HAMAP-Rule MF_00811
Alternative name(s):
Tetrahydrodipicolinate N-succinyltransferase HAMAP-Rule MF_00811
Gene names
Name:dapD HAMAP-Rule MF_00811 EMBL ADE63858.1
Ordered Locus Names:YPZ3_0948 EMBL ADE63858.1
OrganismYersinia pestis (strain Z176003) [Complete proteome] [HAMAP] EMBL ADE63858.1
Taxonomic identifier637386 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia ›

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate. HAMAP-Rule MF_00811 SAAS SAAS023180

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3. HAMAP-Rule MF_00811 SAAS SAAS023180

Subunit structure

Homotrimer By similarity. HAMAP-Rule MF_00811

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00811 SAAS SAAS023180.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. HAMAP-Rule MF_00811

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site1041Substrate By similarity HAMAP-Rule MF_00811
Binding site1411Substrate By similarity HAMAP-Rule MF_00811

Sequences

Sequence LengthMass (Da)Tools
D5B377 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 5BA5F77C11D66282

FASTA27429,937
        10         20         30         40         50         60 
MQQLQNVIET AFERRADITP ANVDTVTREA ITHVIDLLDT GALRVAEKID GQWVTHQWLK 

        70         80         90        100        110        120 
KAVLLSFRIN DNQVMEGAET RYYDKVPMKF AGYDEARFQR EGFRVVPPAT VRKGAFIARN 

       130        140        150        160        170        180 
TVLMPSYVNI GAFVDEGTMV DTWATVGSCA QIGKNVHLSG GVGIGGVLEP LQANPTIIED 

       190        200        210        220        230        240 
NCFVGARSEV VEGVIVEEGS VISMGVFIGQ STRIYDRETG EVHYGRVPAG SVVVSGNLPS 

       250        260        270 
KDGSYSLYCA VIVKKVDAKT RSKVGINELL RTID

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Yersinia pestis from new plague natural foci in China."
Hai R., Yu D., Xia L., Zhu X., Liang Y., Shen X., Zhang E., Zhang H.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Z176003.
[2]"Complete genome sequences of Yersinia pestis from natural foci in China."
Shen X., Wang Q., Xia L., Zhu X., Zhang Z., Liang Y., Cai H., Zhang E., Wei J., Chen C., Song Z., Zhang H., Yu D., Hai R.
J. Bacteriol. 192:3551-3552(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Z176003 EMBL ADE63858.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001593 Genomic DNA. Translation: ADE63858.1.
RefSeqYP_003567120.1. NC_014029.1.

3D structure databases

ProteinModelPortalD5B377.
SMRD5B377. Positions 1-274.
ModBaseSearch...

Proteomic databases

PRIDED5B377.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE63858; ADE63858; YPZ3_0948.
GeneID8990852.
KEGGypz:YPZ3_0948.
PATRIC35469440. VBIYerPes97410_1448.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000003295.
KOK00674.
OMANQWAKKA.

Enzyme and pathway databases

UniPathwayUPA00034; UER00019.

Family and domain databases

Gene3D1.10.166.10. 1 hit.
HAMAPMF_00811. DapD.
InterProIPR005664. DapD_Trfase_Hexpep_rpt_fam.
IPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR023180. THP_succinylTrfase_dom1.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PANTHERPTHR19136:SF52. PTHR19136:SF52. 1 hit.
PfamPF00132. Hexapep. 2 hits.
[Graphical view]
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR00965. dapD. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD5B377_YERPZ
AccessionPrimary (citable) accession number: D5B377
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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