D5AW13 (D5AW13_RICPP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alanine racemase EMBL ADE29602.1
EC=5.1.1.1 EMBL ADE29602.1

Gene names

Name:	alr EMBL ADE29602.1
Ordered Locus Names:	rpr22_CDS089

Organism

Rickettsia prowazekii (strain Rp22) [Complete proteome] [HAMAP]

Taxonomic identifier

449216 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia prowazekii

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 EMBL ADE29602.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D5AW13 [UniParc]. Last modified June 15, 2010. Version 1. Checksum: EBB73D867C97597F	FASTA	404	44,704
	10 20 30 40 50 60 MSLCTLEINL SAIKNNYRLL QDICKTALVG AVVKANGYGL GAMQIAKALI KENCQYFFVA 70 80 90 100 110 120 TSEEGINLRK VLNNDITILV LNGVFTHDAL ELIQYNLTPV LNNLSQIEIW QKFSNLKGKI 130 140 150 160 170 180 LPCYLHFNTG LNRFGLNSDE IEQLINDRDL LKGLDLQYII SHLAASEETG NPYNLIQLNR 190 200 210 220 230 240 FKVYLEYFPN VKASFANSGG IFLGQDYHFD LARPGAALYG LNSLIEVSSN LSYTEEFESN 250 260 270 280 290 300 TAALTTTACI NKCPDVSVRL TPKLPLKGSH TVRLQNPVTL KAPIIDLQNL TLDSHIGYNM 310 320 330 340 350 360 TFTTKRDSVI ATLPLGYADG FSRNFSSQGE VFINSCSVPI VGRVSMDLIN IDVTDLPPSE 370 380 390 400 VFLGQEAEII GNYCTPDKIA SIIGTIGYEV LTSLGSRYKR KYIS

References

[1]

"Genomic, proteomic, and transcriptomic analysis of virulent and avirulent Rickettsia prowazekii reveals its adaptive mutation capabilities." Bechah Y., El Karkouri K., Mediannikov O., Leroy Q., Pelletier N., Robert C., Medigue C., Mege J.L., Raoult D. Genome Res. 20:655-663(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Rp22 EMBL ADE29602.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001584 Genomic DNA. Translation: ADE29602.1.
RefSeq	YP_005998500.1. NC_017560.1.
3D structure databases
ProteinModelPortal	D5AW13.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADE29602; ADE29602; rpr22_CDS089.
GeneID	12587846.
KEGG	rpq:rpr22_CDS089.
PATRIC	36792834. VBIRicPro89493_0092.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 2 hits.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. IPR005728. Rickett_RPE. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR01045. RPE1. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D5AW13_RICPP

Accession

Primary (citable) accession number: D5AW13

Entry history

Integrated into UniProtKB/TrEMBL:	June 15, 2010
Last sequence update:	June 15, 2010
Last modified:	May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)