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D4ZL38 (D4ZL38_SHEVD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlA EMBL BAJ02387.1
Synonyms:ddl HAMAP-Rule MF_00047 EMBL BAJ02387.1
Ordered Locus Names:SVI_2416 EMBL BAJ02387.1
OrganismShewanella violacea (strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12) [Complete proteome] [HAMAP] EMBL BAJ02387.1
Taxonomic identifier637905 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain124 – 329206ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding154 – 20956ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2831Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2961Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2961Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2981Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D4ZL38 [UniParc].

Last modified June 15, 2010. Version 1.
Checksum: 3A02D07EBF5F1C27

FASTA33637,711
        10         20         30         40         50         60 
MSQTNLLLIC GGGGDEHAIS LMSAKFFETS LAKLAHINLL KIELDAQGHY RTQAGELCEL 

        70         80         90        100        110        120 
TNRKQIRFDD VNKASWPVDY VIPCIHGYPG ETGDIQSYFE LIKLPYFGCD SEASRNCFNK 

       130        140        150        160        170        180 
VTAKMWFSAL GIPNTPYIFL NDFNDDAINQ AQQALASWGS IFIKAASQGS SVGCYRVDSP 

       190        200        210        220        230        240 
EELTESLKQA FTYSPYVIVE KTIEARELEV AVYEKDGEII ATQPGEIICG TNTFYTFDEK 

       250        260        270        280        290        300 
YAENSQAETK VVADISESVS QEIREYAVKV FKGMKLSHLS RIDFFLTADN EILLNEINTF 

       310        320        330 
PGLTPISMFP KMLQNHGDNF SDYLNHNIMQ QLSKKD 

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References

[1]"Complete genome sequence and comparative analysis of Shewanella violacea, a psychrophilic and piezophilic bacterium from deep sea floor sediments."
Aono E., Baba T., Ara T., Nishi T., Nakamichi T., Inamoto E., Toyonaga H., Hasegawa M., Takai Y., Okumura Y., Baba M., Tomita M., Kato C., Oshima T., Nakasone K., Mori H.
Mol. Biosyst. 6:1216-1226(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 10179 / CIP 106290 / LMG 19151 / DSS12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP011177 Genomic DNA. Translation: BAJ02387.1.
RefSeqYP_003557165.1. NC_014012.1.

3D structure databases

ProteinModelPortalD4ZL38.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAJ02387; BAJ02387; SVI_2416.
GeneID8966618.
KEGGsvo:SVI_2416.
PATRIC35461075. VBISheVio92117_2333.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.
OMAMEFCVLF.

Enzyme and pathway databases

BioCycSVIO637905:GCRO-2518-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD4ZL38_SHEVD
AccessionPrimary (citable) accession number: D4ZL38
Entry history
Integrated into UniProtKB/TrEMBL: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 19, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)