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D4QFE7

- BGAL_BIFBI

UniProt

D4QFE7 - BGAL_BIFBI

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Protein
Beta-galactosidase BbgII
Gene
bbgII
Organism
Bifidobacterium bifidum
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei122 – 1221Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Active sitei161 – 1611Proton donor By similarity
Active sitei320 – 3201Nucleophile By similarity
Binding sitei328 – 3281Substrate By similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. galactose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase BbgII (EC:3.2.1.23)
Short name:
Beta-gal
Gene namesi
Name:bbgII
OrganismiBifidobacterium bifidum
Taxonomic identifieri1681 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 689689Beta-galactosidase BbgII
PRO_0000407684Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliD4QFE7.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni368 – 3714Substrate binding

Sequence similaritiesi

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

D4QFE7-1 [UniParc]FASTAAdd to Basket

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MSKRRKHSWP QPLKGAESRL WYGGDYNPDQ WPEEVWDDDI RLMKKAGVNL    50
VSVGIFSWAK IEPEEGKYDF DWLDRAIDKL GKAGIAVDLA SATASPPMWL 100
TQAHPEVLWK DERGDTVWPG AREHWRPTSP VFREYALNLC RRMAEHYKGN 150
PYVVAWHVSN EYGCHNRFDY SDDAMRAFQK WCKKRYKTID AVNEAWGTAF 200
WAQHMNDFSE IIPPRYIGDG NFMNPGKLLD YKRFSSDALK ELYIAERDVL 250
ESITPGLPLT TNFMVSAGGS MLDYDDWGAE VDFVSNDHYF TPGEAHFDEV 300
AYAASLMDGI SRKEPWFQME HSTSAVNWRP INYRAEPGSV VRDSLAQVAM 350
GADAICYFQW RQSKAGAEKW HSSMVPHAGE DSQIFRDVCE LGADLGRLSD 400
EGLMGTKTVK SKVAVVFDYE SQWATEYTAN PTQQVDHWTE PLDWFRALAD 450
NGITADVVPV RSDWDSYEIA VLPCVYLLSE ETSRRVREFV ANGGKLFVTY 500
YTGLSDENDH IWLGGYPGSI RDVVGVRVEE FAPMGNDMPG ALDHLDLDNG 550
TVAHDFADVI TSTADTSTVL ASYKAERWTG MNEVPAIVAN GYGDGRTVYV 600
GCRLGRQGLA KSLPAMLGSM GLSDLAGDGR VLRVERADAA AANHFEFVFN 650
RTHEPVTVDV EGEAIAASLA HVDDGRATID PTGVVVLRR 689
Length:689
Mass (Da):77,217
Last modified:June 15, 2010 - v1
Checksum:i886064A1622193CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB542712 Genomic DNA. Translation: BAI94826.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB542712 Genomic DNA. Translation: BAI94826.1 .

3D structure databases

ProteinModelPortali D4QFE7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProi IPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view ]
PIRSFi PIRSF001084. B-galactosidase. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Cooperation of beta-galactosidase and beta-N-acetylhexosaminidase from bifidobacteria in assimilation of human milk oligosaccharides with type 2 structure."
    Miwa M., Horimoto T., Kiyohara M., Katayama T., Kitaoka M., Ashida H., Yamamoto K.
    Glycobiology 20:1402-1409(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: DSM 20082 / JCM 1254 / KCTC 3440.

Entry informationi

Entry nameiBGAL_BIFBI
AccessioniPrimary (citable) accession number: D4QFE7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: June 15, 2010
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi