Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alpha-amylase

Gene

RBR_20490

Organism
Ruminococcus bromii L2-63
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. cation binding Source: InterPro

GO - Biological processi

  1. polysaccharide catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciRBRO657321-WGS:GSU1-1737-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
ORF Names:RBR_20490Imported
OrganismiRuminococcus bromii L2-63Imported
Taxonomic identifieri657321 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus
ProteomesiUP000008954 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD4L985.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

KOiK01176.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006046. Alpha_amylase.
IPR016134. Cellulos_enz_dockerin_1.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF63446. SSF63446. 1 hit.

Sequencei

Sequence statusi: Complete.

D4L985-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKAKKIASL VVASALLTSS FAAITSVNAA EVDSAQTASA DSTLRDKVGD
60 70 80 90 100
GVMLHAFNWS YNTIKENLPA IAAAGYTTVQ TSPVQQPKDY STSGDVTGQW
110 120 130 140 150
WKLYQPISFH IAEESWLGTK DDLKSLCDEA DKYGIKIICD IVSNHIANAD
160 170 180 190 200
EARPDTVSNQ VKKYEPEFYK KRKTYTRTYK GDANDSSVQA VVQGHVSKCP
210 220 230 240 250
DLVTNDTAVQ GYIINLLKEC IDCGVDGFRF DAAKHIETED DGEYASDYWK
260 270 280 290 300
NITTSASSYY TQKTGDDLYI YGEILNNCGA DRSYSSYTKY INVTDNRTGD
310 320 330 340 350
AVLYNVTRGK ASTATNAKYK SGVAASNAVL WAESHDTYEG SSGSSGFSNT
360 370 380 390 400
AGISDENVVK AWAIVASRKD STALFFARPG TALMGNISTD STYKSTAVSE
410 420 430 440 450
INKFHNLFVG QSEKLGSSGD IAYVARGTSG IVLSNCKGTN ASVSISGTGL
460 470 480 490 500
ADGKYTDTVS GAEFTVANGV LTGSIGDTGV AVVYNGTTTP KAINSVESGS
510 520 530 540 550
FRGDTMTLTL SLENATSGTY CLDDSTPVKF TGTTSIRIGS DYKPGETINL
560 570 580 590 600
TVTATDGVKT SSMVYKYAKS TAQESGVYVF FNPANKKGWS APYQVYIFDE
610 620 630 640 650
TTNKGTVYKN ANWPGEAMTL DPATGYYYYE VPKSSSISAD EDDENQAASD
660 670 680 690 700
FDLSTSANTR VIISEKGGEQ YPGRTGTPIS LNGSSKAFSL TKAGTWEDTT
710 720 730 740 750
LTPTKVEIEA TDVTKGSAAE PTTKPVPPTQ PTTAQPATEP SGNAVYGDVN
760 770 780 790 800
GDGDITVVDA TLVQKHVVQL ETLSADKQIL ADVNGDNTIS VVDATLIQKY
810 820 830 840 850
IVQLKDWGRT GDVYQAEQPT TPEPTTAEPT TVKPTAQPTT KPADTYTLYF
860 870 880 890 900
KTKLGWMTSD GVSLFAYDLD TGASYQFEQD TDAYPNVYTV EVPATVSNVS
910 920 930 940 950
VYRSLSEVDE KPVGGDDGNV YNCWDATVSK TNNCITLSND EAVSTAPYVP
960 970 980 990 1000
EQKPAFTLSR VYFDNSKAHY TDVYIYGWAE SGLGNAAAHM NKIAGTDIWY
1010 1020 1030 1040 1050
YDFDTPLSPG SNCFLFKDTE STWKTQTSDL TVADGKNCFR ANPGSKSGGV

WVSYSE
Length:1,056
Mass (Da):113,492
Last modified:May 17, 2010 - v1
Checksum:i364AB77C15E09864
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929051 Genomic DNA. Translation: CBL16180.1.
RefSeqiYP_007781957.1. NC_021013.1.

Genome annotation databases

EnsemblBacteriaiCBL16180; CBL16180; RBR_20490.
GeneIDi15184239.
KEGGirbr:RBR_20490.
PATRICi43158877. VBIRumBro49525_1010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP929051 Genomic DNA. Translation: CBL16180.1.
RefSeqiYP_007781957.1. NC_021013.1.

3D structure databases

ProteinModelPortaliD4L985.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBL16180; CBL16180; RBR_20490.
GeneIDi15184239.
KEGGirbr:RBR_20490.
PATRICi43158877. VBIRumBro49525_1010.

Phylogenomic databases

KOiK01176.

Enzyme and pathway databases

BioCyciRBRO657321-WGS:GSU1-1737-MONOMER.

Family and domain databases

Gene3Di1.10.1330.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006046. Alpha_amylase.
IPR016134. Cellulos_enz_dockerin_1.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF63446. SSF63446. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Ruminococcus bromii L2-63."
    metaHIT consortium -- http://www.metahit.eu/
    Pajon A., Turner K., Parkhill J., Duncan S., Flint H.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: L2-63Imported.

Entry informationi

Entry nameiD4L985_9FIRM
AccessioniPrimary (citable) accession number: D4L985
Entry historyi
Integrated into UniProtKB/TrEMBL: May 17, 2010
Last sequence update: May 17, 2010
Last modified: March 3, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.