Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D4IFW2 (D4IFW2_ERWAE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase HAMAP-Rule MF_00592

Short name=DERA HAMAP-Rule MF_00592
EC=4.1.2.4 HAMAP-Rule MF_00592
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP-Rule MF_00592
Phosphodeoxyriboaldolase HAMAP-Rule MF_00592
Gene names
Name:deoC HAMAP-Rule MF_00592 EMBL CBJ45290.1
Ordered Locus Names:EAM_0615 EMBL CBJ45290.1
OrganismErwinia amylovora (strain ATCC 49946 / CCPPB 0273 / Ea273 / 27-3) [Complete proteome] [HAMAP] EMBL CBJ45290.1
Taxonomic identifier716540 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP-Rule MF_00592 SAAS SAAS011343

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. SAAS SAAS011343 HAMAP-Rule MF_00592

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP-Rule MF_00592 SAAS SAAS011343

Subcellular location

Cytoplasm By similarity SAAS SAAS011343 HAMAP-Rule MF_00592.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. HAMAP-Rule MF_00592

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1671Schiff-base intermediate with acetaldehyde By similarity HAMAP-Rule MF_00592
Active site2011 By similarity HAMAP-Rule MF_00592

Sequences

Sequence LengthMass (Da)Tools
D4IFW2 [UniParc].

Last modified May 18, 2010. Version 1.
Checksum: 0DB4E1AF395D6F96

FASTA25927,438
        10         20         30         40         50         60 
MSDVKTQALR ALQLMDLTTL NDDDTDAKVL ALCRQAKSPA GNTAAICIYP RFIPLARKTL 

        70         80         90        100        110        120 
REQGTPEIRI ATVTNFPHGN DDIEIALAET RAAIAYGADE VDVVFPYRAL MAGNGTVGFE 

       130        140        150        160        170        180 
LVKACKQACS AANVLLKVII ESGELKEDAL IRQASEIAID AGADFIKTST GKVPVNATPA 

       190        200        210        220        230        240 
VAEIMMRTIA AKGVHQQVGF KPAGGVRTAE EAALYLQLAD DILGPDWADA RHFRFGASSL 

       250 
LASLLNAAGF NSAASDSSY 

« Hide

References

[1]"Complete genome sequence of the plant pathogen Erwinia amylovora strain ATCC 49946."
Sebaihia M., Bocsanczy A.M., Biehl B.S., Quail M.A., Perna N.T., Glasner J.D., DeClerck G.A., Cartinhour S., Schneider D.J., Bentley S.D., Parkhill J., Beer S.V.
J. Bacteriol. 192:2020-2021(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49946 / CCPPB 0273 / Ea273 / 27-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN666575 Genomic DNA. Translation: CBJ45290.1.
RefSeqYP_003537705.1. NC_013971.1.

3D structure databases

ProteinModelPortalD4IFW2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBJ45290; CBJ45290; EAM_0615.
GeneID8949116.
KEGGeay:EAM_0615.
PATRIC35412647. VBIErwAmy154257_0592.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000241644.
KOK01619.

Enzyme and pathway databases

BioCycEAMY716540:GJAV-652-MONOMER.
UniPathwayUPA00002; UER00468.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00592. DeoC_type2.
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR023649. DeoC_typeII.
[Graphical view]
PANTHERPTHR10889. PTHR10889. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. deoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD4IFW2_ERWAE
AccessionPrimary (citable) accession number: D4IFW2
Entry history
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: February 19, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)