D4I110 (LPOB_ERWAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Penicillin-binding protein activator LpoB
Short name=PBP activator LpoB

Gene names

Name:	lpoB
Ordered Locus Names:	EAMY_1485

Organism

Erwinia amylovora (strain CFBP1430) [Complete proteome] [HAMAP]

Taxonomic identifier

665029 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Erwinia › Erwinia amylovora

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) By similarity. HAMAP-Rule MF_01889
Subunit structure	Interacts with PBP1b By similarity.
Subcellular location	Cell outer membrane; Lipid-anchor; Periplasmic side By similarity HAMAP-Rule MF_01889.
Sequence similarities	Belongs to the LpoB family.

Ontologies

Keywords
Biological process	Cell shape Peptidoglycan synthesis
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of catalytic activity Inferred from electronic annotation. Source: GOC regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	internal side of cell outer membrane Inferred from electronic annotation. Source: HAMAP plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	enzyme regulator activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 20	20	Potential
	Chain	21 – 198	178	Penicillin-binding protein activator LpoB HAMAP-Rule MF_01889		PRO_0000405783
Amino acid modifications
	Lipidation	21	1	N-palmitoyl cysteine Potential
	Lipidation	21	1	S-diacylglycerol cysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	D4I110 [UniParc]. Last modified May 18, 2010. Version 1. Checksum: 98A3036D89E745D7	FASTA	198	20,829
	10 20 30 40 50 60 MSWIRIRRSG VLLLALVLSG CINQQQQPQP AAPVEPVTPP VNVPQPPKAE PGQNVPPPPK 70 80 90 100 110 120 MQPLNWSATV SPLVGQMLKA DGINAGNVLL VDNVKNSTNG SLQSAKATAA LLNSLENNGQ 130 140 150 160 170 180 FSLVTPQQLA AARQTLGLSA DDSLVSRSKA IGLARYVGAQ YVLYSNAEGD IKSPSLQLQL 190 MLVQTGEIIW SGSGAVVH

References

[1]

"Complete genome sequence of the fire blight pathogen Erwinia amylovora CFBP 1430 and comparison to other Erwinia spp." Smits T.H., Rezzonico F., Kamber T., Blom J., Goesmann A., Frey J.E., Duffy B. Mol. Plant Microbe Interact. 23:384-393(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFBP1430.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN434113 Genomic DNA. Translation: CBA20435.1.
RefSeq	YP_003530843.1. NC_013961.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBA20435; CBA20435; EAMY_1485.
GeneID	8914395.
KEGG	eam:EAMY_1485.
PATRIC	35407108. VBIErwAmy142366_1445.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000119084.
KO	K07337.
Family and domain databases
HAMAP	MF_01889. LpoB.
InterPro	IPR014094. LpoB. [Graphical view]
Pfam	PF13036. DUF3897. 1 hit. [Graphical view]
TIGRFAMs	TIGR02722. lp_. 1 hit.
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LPOB_ERWAC

Accession

Primary (citable) accession number: D4I110

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 8, 2011
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program