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D4HZZ7 (D4HZZ7_ERWAC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP-Rule MF_00038
EC=2.7.8.13 HAMAP-Rule MF_00038
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferase HAMAP-Rule MF_00038
Gene names
Name:mraY HAMAP-Rule MF_00038 EMBL CBA22620.1
Ordered Locus Names:EAMY_2892 EMBL CBA22620.1
OrganismErwinia amylovora (strain CFBP1430) [Complete proteome] [HAMAP] EMBL CBA22620.1
Taxonomic identifier665029 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Erwinia ›

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP-Rule MF_00038

Catalytic activity

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP-Rule MF_00038

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00038

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00038.

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily. HAMAP-Rule MF_00038

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane26 – 4621Helical; By similarity HAMAP-Rule MF_00038
Transmembrane72 – 9221Helical; By similarity HAMAP-Rule MF_00038
Transmembrane94 – 11421Helical; By similarity HAMAP-Rule MF_00038
Transmembrane132 – 15221Helical; By similarity HAMAP-Rule MF_00038
Transmembrane168 – 18821Helical; By similarity HAMAP-Rule MF_00038
Transmembrane199 – 21921Helical; By similarity HAMAP-Rule MF_00038
Transmembrane236 – 25621Helical; By similarity HAMAP-Rule MF_00038
Transmembrane263 – 28321Helical; By similarity HAMAP-Rule MF_00038
Transmembrane288 – 30821Helical; By similarity HAMAP-Rule MF_00038
Transmembrane338 – 35821Helical; By similarity HAMAP-Rule MF_00038

Sequences

Sequence LengthMass (Da)Tools
D4HZZ7 [UniParc].

Last modified May 18, 2010. Version 1.
Checksum: 7FC6797A714B59DD

FASTA36039,942
        10         20         30         40         50         60 
MLVWLAEHLV TFYSGFNVFS YLTFRAIVSL LTALFISLWM GPRMIARLQE MSFGQVVRND 

        70         80         90        100        110        120 
GPESHFSKRG TPTMGGIMIL TSITVSVLLW AYPSNPYVWC VLFVLVGYGI VGFVDDYRKV 

       130        140        150        160        170        180 
VRKDTKGLIA RWKYFWQSAI ALVVAFAMYM IGKGTPATEL VVPFLKDVMP QLGLLYLLLA 

       190        200        210        220        230        240 
YFVIVGTSNA VNLTDGLDGL AIMPTVFVAA GFALVAWATG NVKFAEYLHI PYLRHAGELV 

       250        260        270        280        290        300 
IVCTAIVGAG LGFLWFNTYP AQVFMGDVGS LALGGALGTI AVLLRQEFLL VIMGGVFVVE 

       310        320        330        340        350        360 
TLSVILQVGS FKLRGQRIFR MAPIHHHYEL KGWPEPRVIV RFWIISLMLV LIGLATLKVR

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References

[1]"Complete genome sequence of the fire blight pathogen Erwinia amylovora CFBP 1430 and comparison to other Erwinia spp."
Smits T.H., Rezzonico F., Kamber T., Blom J., Goesmann A., Frey J.E., Duffy B.
Mol. Plant Microbe Interact. 23:384-393(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CFBP1430.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FN434113 Genomic DNA. Translation: CBA22620.1.
RefSeqYP_003532247.1. NC_013961.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBA22620; CBA22620; EAMY_2892.
GeneID8913389.
KEGGeam:EAMY_2892.
PATRIC35409846. VBIErwAmy142366_2791.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000275122.
KOK01000.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

HAMAPMF_00038. MraY.
InterProIPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
PANTHERPTHR22926. PTHR22926. 1 hit.
PTHR22926:SF3. PTHR22926:SF3. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
PF10555. MraY_sig1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00445. mraY. 1 hit.
PROSITEPS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD4HZZ7_ERWAC
AccessionPrimary (citable) accession number: D4HZZ7
Entry history
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info