D4HXG7 (D4HXG7_ERWAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate:folylpolyglutamate synthetase EMBL CBA21668.1
EC=6.3.2.12 EMBL CBA21668.1

Gene names

Name:	folC EMBL CBA21668.1
Ordered Locus Names:	EAMY_2407 EMBL CBA21668.1

Organism

Erwinia amylovora (strain CFBP1430) [Complete proteome] [HAMAP] EMBL CBA21668.1

Taxonomic identifier

665029 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Erwinia › Erwinia amylovora

Protein attributes

Sequence length	420 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS018109 Nucleotide-binding
Molecular function	Ligase EMBL CBA21668.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dihydrofolate biosynthetic process Inferred from electronic annotation. Source: GOC tetrahydrofolylpolyglutamate biosynthetic process Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dihydrofolate synthase activity Inferred from electronic annotation. Source: EC tetrahydrofolylpolyglutamate synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D4HXG7 [UniParc]. Last modified May 18, 2010. Version 1. Checksum: 852DC88F7851ECD1	FASTA	420	45,045
	10 20 30 40 50 60 MDNLPQATSS LAAWLHYLEH LHSQAVDLGL ERVQRVATAL DLLTPAPVVI TVAGTNGKGT 70 80 90 100 110 120 TCRTLETLLL AAGYRVGVYS SPHLVRYTER VRVQGEELAE TAHTASFAAI EAGRAATSLT 130 140 150 160 170 180 YFEFGTLSAL WLFKQARLDV VILEVGLGGR LDATNMVNAD VAVVTSIALD HTDWLGTDRE 190 200 210 220 230 240 SIGREKAGIF RKGKPAVVGE PDMPGSIAVI AAEKGAQLRQ RDRDWSYQLN GDSWSFHDAS 250 260 270 280 290 300 GSIEHLPLPQ VPLPNAATAL AALRASTLEV EEAIIRRSLH QAILPGRFQT VSESPRVILD 310 320 330 340 350 360 VAHNPHAASY LAGRLAEIKG EAKVHAVVGM LHDKDIAGTL ACLAPQVDYW YCAPLEGPRG 370 380 390 400 410 420 ASAEQLMTHL KAAQSFASVT AAWHHALMQA GQQDIVLVCG SFHTVAHVME TMASENGSGK

References

[1]

"Complete genome sequence of the fire blight pathogen Erwinia amylovora CFBP 1430 and comparison to other Erwinia spp." Smits T.H., Rezzonico F., Kamber T., Blom J., Goesmann A., Frey J.E., Duffy B. Mol. Plant Microbe Interact. 23:384-393(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFBP1430.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN434113 Genomic DNA. Translation: CBA21668.1.
RefSeq	YP_003531765.1. NC_013961.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBA21668; CBA21668; EAMY_2407.
GeneID	8912684.
KEGG	eam:EAMY_2407.
PATRIC	35408878. VBIErwAmy142366_2319.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000019982.
KO	K11754.
Family and domain databases
Gene3D	3.40.1190.10. 1 hit. 3.90.190.20. 1 hit.
InterPro	IPR001645. Folylpolyglutamate_synth. IPR018109. Folylpolyglutamate_synth_CS. IPR004101. Mur_ligase_C. IPR013221. Mur_ligase_cen. [Graphical view]
PANTHER	PTHR11136. PTHR11136. 1 hit.
Pfam	PF02875. Mur_ligase_C. 1 hit. PF08245. Mur_ligase_M. 1 hit. [Graphical view]
PIRSF	PIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAM	SSF53244. Mur_ligase_C. 1 hit. SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMs	TIGR01499. folC. 1 hit.
PROSITE	PS01011. FOLYLPOLYGLU_SYNT_1. 1 hit. PS01012. FOLYLPOLYGLU_SYNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D4HXG7_ERWAC

Accession

Primary (citable) accession number: D4HXG7

Entry history

Integrated into UniProtKB/TrEMBL:	May 18, 2010
Last sequence update:	May 18, 2010
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)