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D4HUF8

- D4HUF8_ERWAC

UniProt

D4HUF8 - D4HUF8_ERWAC

Protein
Submitted name:

Bifunctional aspartokinase/homoserine dehydrogenase II

Gene

metL

Organism
Erwinia amylovora (strain CFBP1430)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (18 May 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. aspartate kinase activity Source: UniProtKB-EC
    2. homoserine dehydrogenase activity Source: InterPro
    3. NADP binding Source: InterPro

    GO - Biological processi

    1. aspartate family amino acid biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Enzyme and pathway databases

    BioCyciEAMY665029:GCM3-140-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bifunctional aspartokinase/homoserine dehydrogenase IIImported (EC:2.7.2.4Imported)
    Gene namesi
    Name:metLImported
    Ordered Locus Names:EAMY_0139Imported
    OrganismiErwinia amylovora (strain CFBP1430)Imported
    Taxonomic identifieri665029 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia
    ProteomesiUP000001841: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliD4HUF8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000271594.
    KOiK12525.
    OMAiTLQYPEF.

    Family and domain databases

    Gene3Di3.40.1160.10. 2 hits.
    3.40.50.720. 1 hit.
    InterProiIPR001048. Asp/Glu/Uridylate_kinase.
    IPR005106. Asp/hSer_DH_NAD-bd.
    IPR018042. Aspartate_kinase_CS.
    IPR011147. Bifunc_aspartokin/hSer_DH.
    IPR001342. HDH_cat.
    IPR019811. HDH_CS.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00696. AA_kinase. 1 hit.
    PF00742. Homoserine_dh. 1 hit.
    PF03447. NAD_binding_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000727. ThrA. 1 hit.
    SUPFAMiSSF53633. SSF53633. 1 hit.
    PROSITEiPS00324. ASPARTOKINASE. 1 hit.
    PS01042. HOMOSER_DHGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D4HUF8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSYSAVAKAG SSRQLHKFGG SSLADAKCYQ RVAGIMAEYS QPGDLMVVSA    50
    AGSTTNQLIS WLKLSQSDRL SAHQVQQALR RYQSDLISSL LPPDVAATLI 100
    AELISDLEKL AALLDGVMTD AIYAEVVGHG EIWSARLMSA VLTLRDIEAA 150
    CLDARDFLRA ERAVQPQVDE VKSLPLLQQL MAQYPSQRMV VTGFICGNDA 200
    GETVLLGRNG SDYSATQIGA LAGVTRVTIW SDVAGVYSAD PRKVKDACLL 250
    PLLRLDEASE LARLAAPVLH SRTLQPVSGS DIDLQLRCSY QPEQGSTRIE 300
    RVLASGTGAR IVTSHDDVCL IEFQVPAQHD FASLHKEIDQ LLQRAQVRPL 350
    ATGIHPDRNL LQLCYTSEVV NSALTLLQDA ALPGRLQLRE SMALVAMVGA 400
    GVCRNPLHSH RFWQQMKDQP VEFIWQSQDG ISLVAVLRVG PTEHLIRGLH 450
    QTLFRAEKQI GLVLFGKGNI GSRWLELFAR EQETISARTG FEYILAGVVD 500
    SRRSLLSYQG LDASRAMAFF EDEAVLQDEE SLFLWMRAHP FDDLVVLDVT 550
    ASEILAGQYL DFASYGFHVI GANKVAGAST SDSYRQIRDA FAKTGGHWLY 600
    NATVGAGLPV NHTVRDLRES GDSILSISGI FSGTLSWLFL QFDGTVPFTE 650
    LVDQAWQQGL TEPDPRVDLS GQDVMRKLVI LAREAGYDIE PDQVRVESLV 700
    PVDCQTGSVD HFFDNGDALN DQMLQRFEAA QEMGLVLRYV ARFDANGKAR 750
    VGVEAVRADH PLAALLPCDN VFAIESRWYR DNPLVIRGPG AGRDVTAGAI 800
    QSDLNRLAQL L 811
    Length:811
    Mass (Da):88,837
    Last modified:May 18, 2010 - v1
    Checksum:i8F2E04D2279AD9DA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN434113 Genomic DNA. Translation: CBA19081.1.
    RefSeqiYP_003529497.1. NC_013961.1.

    Genome annotation databases

    EnsemblBacteriaiCBA19081; CBA19081; EAMY_0139.
    GeneIDi8913298.
    KEGGieam:EAMY_0139.
    PATRICi35404418. VBIErwAmy142366_0161.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN434113 Genomic DNA. Translation: CBA19081.1 .
    RefSeqi YP_003529497.1. NC_013961.1.

    3D structure databases

    ProteinModelPortali D4HUF8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CBA19081 ; CBA19081 ; EAMY_0139 .
    GeneIDi 8913298.
    KEGGi eam:EAMY_0139.
    PATRICi 35404418. VBIErwAmy142366_0161.

    Phylogenomic databases

    HOGENOMi HOG000271594.
    KOi K12525.
    OMAi TLQYPEF.

    Enzyme and pathway databases

    BioCyci EAMY665029:GCM3-140-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1160.10. 2 hits.
    3.40.50.720. 1 hit.
    InterProi IPR001048. Asp/Glu/Uridylate_kinase.
    IPR005106. Asp/hSer_DH_NAD-bd.
    IPR018042. Aspartate_kinase_CS.
    IPR011147. Bifunc_aspartokin/hSer_DH.
    IPR001342. HDH_cat.
    IPR019811. HDH_CS.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00696. AA_kinase. 1 hit.
    PF00742. Homoserine_dh. 1 hit.
    PF03447. NAD_binding_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000727. ThrA. 1 hit.
    SUPFAMi SSF53633. SSF53633. 1 hit.
    PROSITEi PS00324. ASPARTOKINASE. 1 hit.
    PS01042. HOMOSER_DHGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the fire blight pathogen Erwinia amylovora CFBP 1430 and comparison to other Erwinia spp."
      Smits T.H., Rezzonico F., Kamber T., Blom J., Goesmann A., Frey J.E., Duffy B.
      Mol. Plant Microbe Interact. 23:384-393(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFBP1430Imported.

    Entry informationi

    Entry nameiD4HUF8_ERWAC
    AccessioniPrimary (citable) accession number: D4HUF8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 18, 2010
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3