Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D4HDK9

- D4HDK9_PROAS

UniProt

D4HDK9 - D4HDK9_PROAS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Thymidine kinase

Gene

tdk

Organism
Propionibacterium acnes (strain SK137)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei87 – 871Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 168ATPUniRule annotation
Nucleotide bindingi86 – 894ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPACN553199:GHRZ-1099-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotationSAAS annotation (EC:2.7.1.21UniRule annotationSAAS annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:HMPREF0675_4109Imported
OrganismiPropionibacterium acnes (strain SK137)Imported
Taxonomic identifieri553199 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium
ProteomesiUP000008987: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD4HDK9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076391.
KOiK00857.
OMAiELKTVCH.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

D4HDK9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAELVFHTGP MDSGKSTLAL QMDHAQSAHD RQGVRYAMHD RSGGARITSR
60 70 80 90 100
IGLSVEAVEV TDSLDLYQDI VSRLSRGGRI DYLICDEAQF YRTKQIDQLA
110 120 130 140 150
RVVDDLDIDV YCFGILADFR TELFPGSKRL VELADRVVEP PVSPLCWCGR
160 170 180 190 200
PATHNARIVD GKLVREGDQV GVGDIGGGSE IHYEVLCRRH HRQGITGEIS
210
RATLSEQTLP FDGSRS
Length:216
Mass (Da):23,926
Last modified:May 18, 2010 - v1
Checksum:iF6055E1F110118C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001977 Genomic DNA. Translation: ADE00600.1.
RefSeqiYP_003581273.1. NC_014039.1.

Genome annotation databases

EnsemblBacteriaiADE00600; ADE00600; HMPREF0675_4109.
GeneIDi9073640.
KEGGipak:HMPREF0675_4109.
PATRICi37226840. VBIProAcn10541_1096.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001977 Genomic DNA. Translation: ADE00600.1 .
RefSeqi YP_003581273.1. NC_014039.1.

3D structure databases

ProteinModelPortali D4HDK9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE00600 ; ADE00600 ; HMPREF0675_4109 .
GeneIDi 9073640.
KEGGi pak:HMPREF0675_4109.
PATRICi 37226840. VBIProAcn10541_1096.

Phylogenomic databases

HOGENOMi HOG000076391.
KOi K00857.
OMAi ELKTVCH.

Enzyme and pathway databases

BioCyci PACN553199:GHRZ-1099-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome of Propionibacterium acnes SK137."
    Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G., Nelson K.E.
    Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SK137Imported.

Entry informationi

Entry nameiD4HDK9_PROAS
AccessioniPrimary (citable) accession number: D4HDK9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: November 26, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3