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D4H827

- D4H827_DENA2

UniProt

D4H827 - D4H827_DENA2

Protein

Alanine racemase

Gene

Dacet_1406

Organism
Denitrovibrio acetiphilus (strain DSM 12809 / N2460)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (18 May 2010)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei40 – 401Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei140 – 1401SubstrateUniRule annotation
    Active sitei258 – 2581Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei306 – 3061Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciDACE522772:GHC2-1419-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Dacet_1406Imported
    OrganismiDenitrovibrio acetiphilus (strain DSM 12809 / N2460)Imported
    Taxonomic identifieri522772 [NCBI]
    Taxonomic lineageiBacteriaDeferribacteresDeferribacteralesDeferribacteraceaeDenitrovibrio
    ProteomesiUP000002012: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei40 – 401N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD4H827.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D4H827-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSKLKALRP TYAEIDLRAF GKNIETAREL SGTDIIAIVK ADAYSHGELE    50
    MCGYAYQKHN CTKFAVATIL EAIILREHLG EGVSIFVLGY IDETFYEEAY 100
    EHNIIFTIND NDTATKYNEF LQRKNLHANV TVKINTGMNR LGFRTDMSWY 150
    EFSSAYPALR PIHIMSHLSS ADTDREYTYN QIEEFHNFIA KNKIRCHTSL 200
    LNSSGIAGYE NKFSLTRPGI MLYGYLDGGY DVKLEKVMRI YSRIVQIQYL 250
    RKGDAVSYSR KFHADRNMAI GVVPIGYADG YPRCLSNKSH VFVDGIKCPV 300
    IGNVCMDMMM VDLTGVNLNG SLKVEVLGDS IDADELAEMA GTISYEILTG 350
    IQNRIPRIYI D 361
    Length:361
    Mass (Da):40,829
    Last modified:May 18, 2010 - v1
    Checksum:i696AFEC12DECAF09
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001968 Genomic DNA. Translation: ADD68176.1.
    RefSeqiYP_003504132.1. NC_013943.1.

    Genome annotation databases

    EnsemblBacteriaiADD68176; ADD68176; Dacet_1406.
    GeneIDi8875754.
    KEGGidap:Dacet_1406.
    PATRICi35352750. VBIDenAce54242_1392.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001968 Genomic DNA. Translation: ADD68176.1 .
    RefSeqi YP_003504132.1. NC_013943.1.

    3D structure databases

    ProteinModelPortali D4H827.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADD68176 ; ADD68176 ; Dacet_1406 .
    GeneIDi 8875754.
    KEGGi dap:Dacet_1406.
    PATRICi 35352750. VBIDenAce54242_1392.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci DACE522772:GHC2-1419-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 12809 / N2460Imported.

    Entry informationi

    Entry nameiD4H827_DENA2
    AccessioniPrimary (citable) accession number: D4H827
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 18, 2010
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3