Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanine racemase

Gene

Dacet_1406

Organism
Denitrovibrio acetiphilus (strain DSM 12809 / N2460)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei40 – 401Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei140 – 1401SubstrateUniRule annotation
Active sitei258 – 2581Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei306 – 3061Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciDACE522772:GHC2-1419-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Dacet_1406Imported
OrganismiDenitrovibrio acetiphilus (strain DSM 12809 / N2460)Imported
Taxonomic identifieri522772 [NCBI]
Taxonomic lineageiBacteriaDeferribacteresDeferribacteralesDeferribacteraceaeDenitrovibrio
ProteomesiUP000002012: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei40 – 401N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD4H827.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

D4H827-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSKLKALRP TYAEIDLRAF GKNIETAREL SGTDIIAIVK ADAYSHGELE
60 70 80 90 100
MCGYAYQKHN CTKFAVATIL EAIILREHLG EGVSIFVLGY IDETFYEEAY
110 120 130 140 150
EHNIIFTIND NDTATKYNEF LQRKNLHANV TVKINTGMNR LGFRTDMSWY
160 170 180 190 200
EFSSAYPALR PIHIMSHLSS ADTDREYTYN QIEEFHNFIA KNKIRCHTSL
210 220 230 240 250
LNSSGIAGYE NKFSLTRPGI MLYGYLDGGY DVKLEKVMRI YSRIVQIQYL
260 270 280 290 300
RKGDAVSYSR KFHADRNMAI GVVPIGYADG YPRCLSNKSH VFVDGIKCPV
310 320 330 340 350
IGNVCMDMMM VDLTGVNLNG SLKVEVLGDS IDADELAEMA GTISYEILTG
360
IQNRIPRIYI D
Length:361
Mass (Da):40,829
Last modified:May 18, 2010 - v1
Checksum:i696AFEC12DECAF09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001968 Genomic DNA. Translation: ADD68176.1.
RefSeqiWP_013010697.1. NC_013943.1.
YP_003504132.1. NC_013943.1.

Genome annotation databases

EnsemblBacteriaiADD68176; ADD68176; Dacet_1406.
GeneIDi8875754.
KEGGidap:Dacet_1406.
PATRICi35352750. VBIDenAce54242_1392.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001968 Genomic DNA. Translation: ADD68176.1.
RefSeqiWP_013010697.1. NC_013943.1.
YP_003504132.1. NC_013943.1.

3D structure databases

ProteinModelPortaliD4H827.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADD68176; ADD68176; Dacet_1406.
GeneIDi8875754.
KEGGidap:Dacet_1406.
PATRICi35352750. VBIDenAce54242_1392.

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.
BioCyciDACE522772:GHC2-1419-MONOMER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 12809 / N2460Imported.

Entry informationi

Entry nameiD4H827_DENA2
AccessioniPrimary (citable) accession number: D4H827
Entry historyi
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: February 4, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.