SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D4GV77

- D4GV77_HALVD

UniProt

D4GV77 - D4GV77_HALVD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Ribulose bisphosphate carboxylase
Gene
rbcL, HVO_0970, C498_13921
Organism
Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the addition of molecular CO2 and H2O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase By similarity.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei150 – 1501Proton acceptor By similarityUniRule annotation
Binding sitei152 – 1521Substrate By similarityUniRule annotation
Metal bindingi176 – 1761Magnesium; via carbamate group By similarityUniRule annotation
Metal bindingi178 – 1781Magnesium By similarityUniRule annotation
Metal bindingi179 – 1791Magnesium By similarityUniRule annotation
Active sitei268 – 2681Proton acceptor By similarityUniRule annotation
Binding sitei269 – 2691Substrate By similarityUniRule annotation
Binding sitei301 – 3011Substrate By similarityUniRule annotation
Sitei309 – 3091Transition state stabilizer By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. ribulose-bisphosphate carboxylase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciHVOL309800:GCOK-974-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylaseUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCOUniRule annotation
Gene namesi
Name:rbcLUniRule annotationImported
Ordered Locus Names:HVO_0970Imported
ORF Names:C498_13921Imported
OrganismiHaloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)Imported
Taxonomic identifieri309800 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeHaloferax
ProteomesiUP000008243: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei176 – 1761N6-carboxylysine By similarityUniRule annotation

Interactioni

Subunit structurei

Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits By similarity.UniRule annotation

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni337 – 3393Substrate binding By similarityUniRule annotation
Regioni359 – 3624Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Belongs to the RuBisCO large chain family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000230831.
KOiK01601.
OMAiFTQDWAS.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProiIPR017712. RuBisCO_III.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsiTIGR03326. rubisco_III. 1 hit.

Sequencei

Sequence statusi: Complete.

D4GV77-1 [UniParc]FASTAAdd to Basket

« Hide

MGITYEDFLD LDYEPTDEDL VCTFRIDPAT GMSTEAAASR VASESSNGTW    50
AALQTGADFT DMGATTFDID GDLIRVAYPA GLFEPGNMPQ VLSCIAGNIM 100
GMKAVDTIRL LDCEWPESVV SAYPGPLYGS SVREEIFGVT DRPITATVPK 150
PKVGLSTAAH AQVGYDAWVG GVDLLKDDEN LTDQAFNPFS DRLTESLSLR 200
DDAEDETGEK KSYLINVTAD TQTMLDRVDE VAAQGGEYVM VDIITAGWAG 250
LQTVRERTEK HGLAIHAHRA MHAAFDRLPA HGVSMRVLAQ VSRLCGVDQL 300
HTGTAGLGKL ANEDTVGINE WLAGDLHGAT DVLPVASGGL HPGLLPDLLD 350
ATGTNVCVQL GGGIHGHPDG TRAGAVALRS AIDAYVEGRA ITEAAEETPE 400
LAVALDKWGT ETPR 414
Length:414
Mass (Da):43,922
Last modified:May 18, 2010 - v1
Checksum:i436AC5738813777B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001956 Genomic DNA. Translation: ADE04153.1.
AOHU01000093 Genomic DNA. Translation: ELY27227.1.
RefSeqiYP_003535027.1. NC_013967.1.

Genome annotation databases

EnsemblBacteriaiADE04153; ADE04153; HVO_0970.
ELY27227; ELY27227; C498_13921.
GeneIDi8926563.
KEGGihvo:HVO_0970.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001956 Genomic DNA. Translation: ADE04153.1 .
AOHU01000093 Genomic DNA. Translation: ELY27227.1 .
RefSeqi YP_003535027.1. NC_013967.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADE04153 ; ADE04153 ; HVO_0970 .
ELY27227 ; ELY27227 ; C498_13921 .
GeneIDi 8926563.
KEGGi hvo:HVO_0970.

Phylogenomic databases

HOGENOMi HOG000230831.
KOi K01601.
OMAi FTQDWAS.

Enzyme and pathway databases

BioCyci HVOL309800:GCOK-974-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProi IPR017712. RuBisCO_III.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsi TIGR03326. rubisco_III. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2.
  2. "The Complete Genome Sequence of Haloferax volcanii DS2, a Model Archaeon."
    Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R., Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J., Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.
    PLoS ONE 5:E9605-E9605(2010)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DS2Imported.
  3. Becker E.A., Seitzer P., Tritt A., Larsen D., Yao A., Wu D., Darling A., Eisen J.A., Facciotti M.T.
    Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DS2Imported.

Entry informationi

Entry nameiD4GV77_HALVD
AccessioniPrimary (citable) accession number: D4GV77
Entry historyi
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: September 3, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O2 to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi