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D4GG06

- D4GG06_PANAM

UniProt

D4GG06 - D4GG06_PANAM

Protein

Thymidine kinase

Gene

tdk

Organism
Pantoea ananatis (strain LMG 20103)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (18 May 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei104 – 1041Proton acceptorUniRule annotation
    Metal bindingi161 – 1611ZincUniRule annotation
    Metal bindingi163 – 1631ZincUniRule annotation
    Metal bindingi198 – 1981ZincUniRule annotation
    Metal bindingi201 – 2011ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi25 – 328ATPUniRule annotation
    Nucleotide bindingi103 – 1064ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotation, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPANA706191:GJNK-2148-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotationImported
    Ordered Locus Names:PANA_2090Imported
    OrganismiPantoea ananatis (strain LMG 20103)Imported
    Taxonomic identifieri706191 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePantoea
    ProteomesiUP000001702: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD4GG06.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000076391.
    KOiK00857.
    OMAiELKTVCH.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D4GG06-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVKSALFFHR IRESAQMAQL YFYYSAMNAG KSTALLQSSY NYQERGMRTL    50
    VYTAEIDNRF GAGKVSSRIG LSSPAVLYNA ASQLDVEIAQ EHARQPVHCV 100
    LVDESQFLTR EQVKALSDVV DNLDIPVLCY GLRTDFLGEL FTGSQYLLAW 150
    ADKLVELKTV CHCGRKAGMV LRLDSDGKPF REGEQVVIGG NERYISVCRK 200
    HYKKAIEQGC LQAIHGAQTP VGNK 224
    Length:224
    Mass (Da):25,005
    Last modified:May 18, 2010 - v1
    Checksum:iCEB6AE552DC0198C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001875 Genomic DNA. Translation: ADD77257.1.
    RefSeqiWP_013025967.1. NC_013956.2.
    YP_003520385.1. NC_013956.2.

    Genome annotation databases

    EnsemblBacteriaiADD77257; ADD77257; PANA_2090.
    GeneIDi8895957.
    KEGGipam:PANA_2090.
    PATRICi35385145. VBIPanAna151616_2167.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001875 Genomic DNA. Translation: ADD77257.1 .
    RefSeqi WP_013025967.1. NC_013956.2.
    YP_003520385.1. NC_013956.2.

    3D structure databases

    ProteinModelPortali D4GG06.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADD77257 ; ADD77257 ; PANA_2090 .
    GeneIDi 8895957.
    KEGGi pam:PANA_2090.
    PATRICi 35385145. VBIPanAna151616_2167.

    Phylogenomic databases

    HOGENOMi HOG000076391.
    KOi K00857.
    OMAi ELKTVCH.

    Enzyme and pathway databases

    BioCyci PANA706191:GJNK-2148-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Pantoea ananatis LMG20103, the causative agent of Eucalyptus blight and dieback."
      De Maayer P., Chan W.Y., Venter S.N., Toth I.K., Birch P.R., Joubert F., Coutinho T.A.
      J. Bacteriol. 192:2936-2937(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LMG 20103Imported.

    Entry informationi

    Entry nameiD4GG06_PANAM
    AccessioniPrimary (citable) accession number: D4GG06
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 18, 2010
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3