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D4GG06

- D4GG06_PANAM

UniProt

D4GG06 - D4GG06_PANAM

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Protein

Thymidine kinase

Gene
tdk, PANA_2090
Organism
Pantoea ananatis (strain LMG 20103)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei104 – 1041Proton acceptor By similarityUniRule annotation
Metal bindingi161 – 1611Zinc By similarityUniRule annotation
Metal bindingi163 – 1631Zinc By similarityUniRule annotation
Metal bindingi198 – 1981Zinc By similarityUniRule annotation
Metal bindingi201 – 2011Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi25 – 328ATP By similarityUniRule annotation
Nucleotide bindingi103 – 1064ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotations, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciPANA706191:GJNK-2148-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:PANA_2090Imported
OrganismiPantoea ananatis (strain LMG 20103)Imported
Taxonomic identifieri706191 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePantoea
ProteomesiUP000001702: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliD4GG06.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076391.
KOiK00857.
OMAiELKTVCH.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4GG06-1 [UniParc]FASTAAdd to Basket

« Hide

MVKSALFFHR IRESAQMAQL YFYYSAMNAG KSTALLQSSY NYQERGMRTL    50
VYTAEIDNRF GAGKVSSRIG LSSPAVLYNA ASQLDVEIAQ EHARQPVHCV 100
LVDESQFLTR EQVKALSDVV DNLDIPVLCY GLRTDFLGEL FTGSQYLLAW 150
ADKLVELKTV CHCGRKAGMV LRLDSDGKPF REGEQVVIGG NERYISVCRK 200
HYKKAIEQGC LQAIHGAQTP VGNK 224
Length:224
Mass (Da):25,005
Last modified:May 18, 2010 - v1
Checksum:iCEB6AE552DC0198C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001875 Genomic DNA. Translation: ADD77257.1.
RefSeqiWP_013025967.1. NC_013956.2.
YP_003520385.1. NC_013956.2.

Genome annotation databases

EnsemblBacteriaiADD77257; ADD77257; PANA_2090.
GeneIDi8895957.
KEGGipam:PANA_2090.
PATRICi35385145. VBIPanAna151616_2167.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001875 Genomic DNA. Translation: ADD77257.1 .
RefSeqi WP_013025967.1. NC_013956.2.
YP_003520385.1. NC_013956.2.

3D structure databases

ProteinModelPortali D4GG06.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADD77257 ; ADD77257 ; PANA_2090 .
GeneIDi 8895957.
KEGGi pam:PANA_2090.
PATRICi 35385145. VBIPanAna151616_2167.

Phylogenomic databases

HOGENOMi HOG000076391.
KOi K00857.
OMAi ELKTVCH.

Enzyme and pathway databases

BioCyci PANA706191:GJNK-2148-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Pantoea ananatis LMG20103, the causative agent of Eucalyptus blight and dieback."
    De Maayer P., Chan W.Y., Venter S.N., Toth I.K., Birch P.R., Joubert F., Coutinho T.A.
    J. Bacteriol. 192:2936-2937(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LMG 20103Imported.

Entry informationi

Entry nameiD4GG06_PANAM
AccessioniPrimary (citable) accession number: D4GG06
Entry historyi
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: September 3, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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