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D4DEJ7 (DPEP1_TRIVH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative dipeptidase TRV_05564

EC=3.4.13.19
Gene names
ORF Names:TRV_05564
OrganismTrichophyton verrucosum (strain HKI 0517) [Complete proteome]
Taxonomic identifier663202 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaemitosporic ArthrodermataceaeTrichophyton

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes a wide range of dipeptides By similarity.

Catalytic activity

Hydrolysis of dipeptides.

Cofactor

Zinc By similarity.

Sequence similarities

Belongs to the peptidase M19 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 414394Putative dipeptidase TRV_05564
PRO_0000411215

Sites

Metal binding451Zinc 1; catalytic By similarity
Metal binding471Zinc 1; catalytic By similarity
Metal binding1571Zinc 1; catalytic By similarity
Metal binding1571Zinc 2; catalytic By similarity
Metal binding2281Zinc 2; catalytic By similarity
Metal binding2491Zinc 2; catalytic By similarity
Binding site1841Substrate By similarity
Binding site2601Substrate By similarity
Binding site3201Substrate By similarity

Amino acid modifications

Glycosylation3921N-linked (GlcNAc...) Potential
Disulfide bond96 ↔ 186 By similarity

Sequences

Sequence LengthMass (Da)Tools
D4DEJ7 [UniParc].

Last modified May 18, 2010. Version 1.
Checksum: 938DC330AB7F222A

FASTA41445,407
        10         20         30         40         50         60 
MAALFVSLLA LTSLVPVQGA ATVPQTDYAK RAERVLKSAP LIDGHNDLLY AIRRSTNDQI 

        70         80         90        100        110        120 
YDGKLPFETS LKGHTDLPRM RKGRMGGQFW SVFIACPSDP NAPINTPKFA TRDTLEQIDV 

       130        140        150        160        170        180 
ARRLVDKYSK DLMYCDNPGC AKRAFREGKI GSFIGIEGGH QVGSSIAALR QAFYAGARYM 

       190        200        210        220        230        240 
TLTHNCDNAW ATAASTVRAG KPDLGMTDFG PALIKEMNRL GMLVDLSHVS HQTMRDVLKI 

       250        260        270        280        290        300 
TKAPVIFSHS SAYEVSKHLR NVPDDVLKTV AKNNGVVMVT FVSSFVKVDD PDSADVNTVV 

       310        320        330        340        350        360 
KHIFHIAEVA GWDHVGLGGD YDGTTELPKG LEDVSKYPYL IEKVLEAGAT EEQARKLVGE 

       370        380        390        400        410 
NVLRVWTEVE QIAKKIQRSG VLPVEEVWKG RNGTALSERS TFIEGPAPLE YGCD 

« Hide

References

[1]"Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi."
Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S., Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O., Schroeckh V. expand/collapse author list , Hertweck C., Hube B., White T.C., Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.
Genome Biol. 12:R7.1-R7.16(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HKI 0517.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
ACYE01000298 Genomic DNA. Translation: EFE39721.1.
RefSeqXP_003020339.1. XM_003020293.1.

3D structure databases

ProteinModelPortalD4DEJ7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9584076.
KEGGtve:TRV_05564.

Phylogenomic databases

KOK01273.
OrthoDBEOG7XM371.

Family and domain databases

InterProIPR008257. Renal_dipep_fam.
[Graphical view]
PANTHERPTHR10443. PTHR10443. 1 hit.
PfamPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEPS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDPEP1_TRIVH
AccessionPrimary (citable) accession number: D4DEJ7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: May 18, 2010
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries