ID   D4D4A1_TRIVH            Unreviewed;       482 AA.
AC   D4D4A1;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Histone-lysine N-methyltransferase Clr4 {ECO:0000313|EMBL:EFE43356.1};
GN   ORFNames=TRV_01916 {ECO:0000313|EMBL:EFE43356.1};
OS   Trichophyton verrucosum (strain HKI 0517).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663202 {ECO:0000313|EMBL:EFE43356.1, ECO:0000313|Proteomes:UP000008383};
RN   [1] {ECO:0000313|Proteomes:UP000008383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HKI 0517 {ECO:0000313|Proteomes:UP000008383};
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFE43356.1}.
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DR   EMBL; ACYE01000100; EFE43356.1; -; Genomic_DNA.
DR   RefSeq; XP_003023974.1; XM_003023928.1.
DR   AlphaFoldDB; D4D4A1; -.
DR   GeneID; 9582667; -.
DR   KEGG; tve:TRV_01916; -.
DR   HOGENOM; CLU_020840_11_1_1; -.
DR   OrthoDB; 5481936at2759; -.
DR   Proteomes; UP000008383; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46223:SF3; HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR46223; HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:EFE43356.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFE43356.1}.
FT   DOMAIN          299..429
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   DOMAIN          440..456
FT                   /note="Post-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50868"
FT   REGION          40..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          457..482
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   482 AA;  54540 MW;  318937D095E2235D CRC64;
     MPTQIPGQAV TRQLDTVIYS EHFWQPEVIS SRLLKAFISP EDDRQRQLPS KPPSKPGRAV
     VDKGSTSSSS RPQSKASNVS VVIPVPPRRP SPSPVTTSRK RSLSSDGDIN KALSRKLTAT
     KIPDHHGLSD FYAVGNEEVK RPYLKLKTFD PKKTEIPRSS KRYIPPKRRS DKESACSRLE
     ELYNKKLQRI KGPPVRFKAG KIAKEIDFNF DFIDSYKIHS GVNQIDPEFL WGCDCTKCDA
     ECDCLSKDLI HYEKGQRVRA VLKSEILNKR TALIRECSSR CKCSGVNCWN HVVFRGRQVE
     LEVFQTKNRG FGVRSPHSIE RGQFIDTYVG EVIEPSTSDA REEAIDVEKY SSYLFSLDYF
     PAEEYEKEKD IYVVDGRKFG SITRFINHSC NPNCKMFPAT QTDDHGVYQL AFFAVRDIPA
     GTELTFDYHP GWEGGDVDPD ATKCLCGEKN CRGQLWPAKR KTTRPGEDSS SGESSEESED
     DE
//