Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D4ANI5 (D4ANI5_ARTBC) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length462 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively By similarity. PIRNR PIRNR038800

Catalytic activity

L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. PIRNR PIRNR038800

L-kynurenine + H2O = anthranilate + L-alanine. PIRNR PIRNR038800

Cofactor

Pyridoxal phosphate By similarity. PIRNR PIRNR038800

Pathway

Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. PIRNR PIRNR038800

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3. PIRNR PIRNR038800

Subunit structure

Homodimer By similarity. PIRNR PIRNR038800

Subcellular location

Cytoplasm By similarity PIRNR PIRNR038800.

Sequence similarities

Belongs to the kynureninase family. PIRNR PIRNR038800

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Sequences

Sequence LengthMass (Da)Tools
D4ANI5 [UniParc].

Last modified May 18, 2010. Version 1.
Checksum: D96BAC95B3EC56B1

FASTA46251,761
        10         20         30         40         50         60 
MDFSKDPSSL TREYARNLDE QDPLRDFRKE FIIPSKADLT RTTLAPPTGE EERKLEESCV 

        70         80         90        100        110        120 
YLCGNSLGLQ PVSTSEHVNS YLRSWALKGV LGHTEPHTDQ LTAEWLNIDD RAPELMAPLV 

       130        140        150        160        170        180 
GAKESEVALM GTLTSNLHLL MASFYKPTKE RYKIIFEGKA FPSDHFAIES QARHHGLDPE 

       190        200        210        220        230        240 
DAMVLIEPVS EDYPVLETSQ ILSVIDAHAD TAALILLPGI QYYTGQFFDM KTITAHAHSK 

       250        260        270        280        290        300 
GLMVGWDCAH AVGNVELQFH DWDVDFAAWC SYKYLNSGAG AMAGLFVHEK HGMVTEDSFR 

       310        320        330        340        350        360 
PRLSGWWGSD KSSRFIMDNK FVPRPGAAGY QVSNPSALDL AAVTASLKVF NKATMQALRR 

       370        380        390        400        410        420 
KSVKLTAYLE YLIDREFPSK SERPFTIITP SDPDMRGAQL SLRLRAGLLD PVFSCLLRNG 

       430        440        450        460 
VVLDERRPDV IRVAPAPLYN SFEDVWLFVR ELRVACDEAT AR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
ABSU01000003 Genomic DNA. Translation: EFE35746.1.
RefSeqXP_003016391.1. XM_003016345.1.

3D structure databases

ProteinModelPortalD4ANI5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9521874.
KEGGabe:ARB_05790.

Phylogenomic databases

KOK01556.
OrthoDBEOG7V1G0J.

Enzyme and pathway databases

UniPathwayUPA00253; UER00329.
UPA00334; UER00455.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01970. Kynureninase.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR010111. Kynureninase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR14084. PTHR14084. 1 hit.
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFPIRSF038800. KYNU. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR01814. kynureninase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD4ANI5_ARTBC
AccessionPrimary (citable) accession number: D4ANI5
Entry history
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)