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Protein

DNA ligase

Gene

ARB_05408

Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ARB_05408Imported
OrganismiArthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)Imported
Taxonomic identifieri663331 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
ProteomesiUP000008866: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliD4AMF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4AMF5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGPLKKKRK VDSTGVPQNT RSIASYFRAG NKATSSQIIS TEHHRLTDEQ
60 70 80 90 100
LARKLQKEWN KKSQDESESS TPGHRATENL QEEKLRASDE VADASSSSDK
110 120 130 140 150
GSLADTPALT PGKENKPKGI LSLQSSSTAE DTISFSLPFD LSPLEFDPHE
160 170 180 190 200
QKEKLQAHWD AEGGKASYAI LARAFSLVNG TQSRIKIVDI LVNLLRLIIV
210 220 230 240 250
GDPQSLLPAV WLATNAFAPP YVPIELGLGG SAISKALKRA YGLDNQGLKA
260 270 280 290 300
LYNKHGDAGD VAFEAKKKQS FTLRRPKPLT IRSVYDALMK IANSKGTGSQ
310 320 330 340 350
ETKQRIVEKL LQDTRGAEES RYIVRTLVQH LRIGAVKTTI LIALARAFLY
360 370 380 390 400
SKPPAATFPL RSRAELMSLS KEELSNIYSQ AEETIKACYA RHPNYNMIVP
410 420 430 440 450
CLLENGVSAE LLTKCGITLH VPLLPMLGSI TRDLPQMLTR LHGRSFTCEY
460 470 480 490 500
KYDGQRAQVH CDAAGKVSIF SRHLELMTDK YPDLVSLVPQ IRSGAVSSFI
510 520 530 540 550
MEGEVVAVNN ETGELLPFQT LTNRAKKNVE IGSIKVNVCL FSFDLMYLNG
560 570 580 590 600
QPLLDRTFRE RRELLRSLFV EIPNQFTWVK SIDAFPSDSD AVLNFFNDAL
610 620 630 640 650
QVKCEGIMVK VLDDKPVDRL LQAEDTATAL GDGELLPPEE DKKQESTDTA
660 670 680 690 700
EKQRGNRKRP LLSTYEPDKR LESWLKVKKD YSASSETLDL IPIAAWHGQG
710 720 730 740 750
RKAKWWSPIL LAVRNPETGS LEAVTKCMSG FTDKFYEANK EKYAEGSDNI
760 770 780 790 800
ISRPSYVEYC GEPEVWFQPQ EVWEMAFADI TLSPTYTAAI GLVSDERGLS
810 820 830 840
LRFPRFLRVR EDKSIDEAST SDYLAHLWDK QAERAKVAEP RAGD
Length:844
Mass (Da):94,091
Last modified:May 18, 2010 - v1
Checksum:i5FC84138AEE11C9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABSU01000003 Genomic DNA. Translation: EFE35366.1.
RefSeqiXP_003016011.1. XM_003015965.1.

Genome annotation databases

GeneIDi9523919.
KEGGiabe:ARB_05408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABSU01000003 Genomic DNA. Translation: EFE35366.1.
RefSeqiXP_003016011.1. XM_003015965.1.

3D structure databases

ProteinModelPortaliD4AMF5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9523919.
KEGGiabe:ARB_05408.

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4681 / CBS 112371Imported.

Entry informationi

Entry nameiD4AMF5_ARTBC
AccessioniPrimary (citable) accession number: D4AMF5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: January 7, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.