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Protein

DNA ligase

Gene

ARB_04383

Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ARB_04383Imported
OrganismiArthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)Imported
Taxonomic identifieri663331 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeTrichophyton
Proteomesi
  • UP000008866 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi663331.XP_003017502.1

Structurei

3D structure databases

ProteinModelPortaliD4AJD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini413 – 538DNA_LIGASE_A3InterPro annotationAdd BLAST126
Domaini723 – 807BRCTInterPro annotationAdd BLAST85
Domaini897 – 1010BRCTInterPro annotationAdd BLAST114

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0966 Eukaryota
COG1793 LUCA
KOiK10777
OrthoDBiEOG092C18KW

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di1.10.3260.10, 1 hit
3.40.50.10190, 2 hits
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR029710 LIG4
IPR012340 NA-bd_OB-fold
PANTHERiPTHR10459:SF7 PTHR10459:SF7, 1 hit
PfamiView protein in Pfam
PF16589 BRCT_2, 1 hit
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
SSF52113 SSF52113, 2 hits
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 2 hits
PS00697 DNA_LIGASE_A1, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

D4AJD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPNPGGAIR ETERELDEKP RNHGQTLPFH DLFISLFNPL NDLKKKPAGP
60 70 80 90 100
PAARRKAGPT GRNNLSPHEL RRNVIERFIS RWRQQVGNDF FPAFRLIVPE
110 120 130 140 150
KDRDRAMYGL KEKAIGKLLV KVMKIDKNSE DGYNLLNWKL PGQRAATAMT
160 170 180 190 200
GDFAGRCFEV ISKRPLRTEV GDMSIADVNS RLDDLAVASK EDAQLPILAE
210 220 230 240 250
FYRRMNPEEM MWLIRIILRQ MKVGATERTF FEIWHPDAES LFNISSSLRR
260 270 280 290 300
VCWELYLPSI RLEADEARVT LMQCFQPQLA QFQMHSFQKI IERMRLAEDD
310 320 330 340 350
PEFWIEEKLD GERMQLHMET NSSIPGGKRF EFWSRKAKEY TYLYGNGFYD
360 370 380 390 400
DNGSLTRHLK NAFADGVESI ILDGEMITWD PEQDAPVPFG TLKTAALAEQ
410 420 430 440 450
RNPFSASGHR PLFRIFDIVY LNGKPLTRYT LRDRRRALEA SVIPVHRRFE
460 470 480 490 500
IHPYQVGKSA SDIEPLLRKV VAEASEGLVL KNPNSPYRLN ERNDDWMKVK
510 520 530 540 550
PDYMTEFGES LDCIVVGGYY GSGKRGGNIS SYLCGLRVDD THAEDGTNPM
560 570 580 590 600
KCYSFCKVGG GFTAADYANI RHHTDGKWHD WDPKKPPTEY IELAGGDAQH
610 620 630 640 650
ERPDVWIKPD DSIVVCVKAA AVTPSDQFRL GLTVRFPRFK RLRMDKDWQS
660 670 680 690 700
ALSVQEFMDL KAGAEQEKKE KDFQVDNSRR KKTKRSKKKE LTVAGSGEPN
710 720 730 740 750
VAYVGSKTHI FDGLSFCGLK IQALEVNYAN IFIVVMTESV KPMKKSKADL
760 770 780 790 800
EQLIKANGGK IYQTNNAAKD TYCIADRRTV KVASLQKSGL ENVIRPCWIS
810 820 830 840 850
DCISQNEHDI GESSILLPLE PRHMFFTKED QKEEISNNVD KYDDSFARDT
860 870 880 890 900
SIAELTEILH KMDAISDISG EERLDIMSDL TLDGDQGSVH SDVEGWLFKN
910 920 930 940 950
LTIFFAPCSH LSSVPGEPYV DALSIRQQLA RNITIFTGAT VTDQQKNNRI
960 970 980 990 1000
THVIVDPSAD RDPETGKAKN YTTLRSEFAT RRAIPHFVTV QWVEECWKEK
1010 1020
TLVDEERMYS MPAIALPGLC
Length:1,020
Mass (Da):116,241
Last modified:May 18, 2010 - v1
Checksum:iE34AC539D072D3A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABSU01000001 Genomic DNA Translation: EFE36857.1
RefSeqiXP_003017502.1, XM_003017456.1

Genome annotation databases

EnsemblFungiiEFE36857; EFE36857; ARB_04383
GeneIDi9524612
KEGGiabe:ARB_04383

Similar proteinsi

Entry informationi

Entry nameiD4AJD4_ARTBC
AccessioniPrimary (citable) accession number: D4AJD4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 18, 2010
Last sequence update: May 18, 2010
Last modified: May 23, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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