D4AE09 (D4AE09_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cytochrome P450, family 39, subfamily a, polypeptide 1 (Predicted), isoform CRA_a EMBL EDM18705.1

Submitted name:
Protein Cyp39a1 Ensembl ENSRNOP00000014051

Gene names

Name:	Cyp39a1 Ensembl ENSRNOP00000014051
Synonyms:	Cyp39a1_predicted EMBL EDM18705.1
ORF Names:	rCG_43541 EMBL EDM18705.1

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000014051

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	465 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Heme SAAS SAAS002403 Iron Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	bile acid biosynthetic process Inferred from electronic annotation. Source: Compara cholesterol catabolic process Inferred from electronic annotation. Source: Compara
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro oxysterol 7-alpha-hydroxylase activity Inferred from electronic annotation. Source: Compara steroid 7-alpha-hydroxylase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D4AE09 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 09B7E3BA9FA8C41E	FASTA	465	53,339
	10 20 30 40 50 60 MGIMELFSPI AIAVLGSCVL FLFSRWKNLR GPPCIQGWIP WIGAGFEFGK APLEFIEKAR 70 80 90 100 110 120 IKYGPVFTVF AVGKRMTFVT EEEGINVLLK SKHVDFELAV QRPLYHTAWI PKNIFFALHE 130 140 150 160 170 180 KLYVLMKGKM GTFNTHHFTG QLTEEFHDQL EGLGTHGTMD LNDFVRYLLY PATLNTLFMK 190 200 210 220 230 240 GLFLTDKRKI KEFYQHFKTY DEGFEYGSQL PEWLLRNWSK SKRWLLALFE KNIGDIKTHG 250 260 270 280 290 300 SAGHSETLLQ AVLGMVETET RLHSPNYGLV MLWASLANAA PIAFWTLAYI LSHPDLHRTI 310 320 330 340 350 360 VESISSVFGT AGKDKIQVSE NDLKKLLLIK WCILESIRLR APGVITRKVV KPVKILNHTV 370 380 390 400 410 420 PSGDLLMLSP FWLHRNPKYF PEPESFKPER WKEANLDKYI FLDYFMAFGG GKFQCPGRWF 430 440 450 460 ALLEIQLCII LVLYKYECSL LDPLPKQAKF SSFGGCPPAS REMPN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000014051.
[2]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDM18705.1.
[3]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDM18705.1.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000014051.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06058914 Genomic DNA. No translation available. AABR06058915 Genomic DNA. No translation available. AABR06058916 Genomic DNA. No translation available. AABR06058917 Genomic DNA. No translation available. AABR06058918 Genomic DNA. No translation available. CH473987 Genomic DNA. Translation: EDM18705.1.
IPI	IPI00371777.
RefSeq	NP_001100363.1. NM_001106893.1.
UniGene	Rn.153360.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000014051; ENSRNOP00000014051; ENSRNOG00000010519.
GeneID	301264.
KEGG	rno:301264.
UCSC	RGD:1307471. rat.
Organism-specific databases
CTD	51302.
RGD	1307471. Cyp39a1.
Phylogenomic databases
GeneTree	ENSGT00550000074551.
KO	K07439.
OrthoDB	EOG49KFQX.
Family and domain databases
Gene3D	1.10.630.10. 1 hit.
InterPro	IPR001128. Cyt_P450. IPR002403. Cyt_P450_E_grp-IV. [Graphical view]
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00465. EP450IV.
SUPFAM	SSF48264. Cytochrome_P450. 1 hit.
ProtoNet	Search...
Other
NextBio	648423.

Entry information

Entry name

D4AE09_RAT

Accession

Primary (citable) accession number: D4AE09

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	April 3, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)