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D4AE09

- D4AE09_RAT

UniProt

D4AE09 - D4AE09_RAT

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Protein
Submitted name:

Cytochrome P450, family 39, subfamily a, polypeptide 1 (Predicted), isoform CRA_a

Gene

Cyp39a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. oxysterol 7-alpha-hydroxylase activity Source: Ensembl
  4. steroid 7-alpha-hydroxylase activity Source: Ensembl

GO - Biological processi

  1. bile acid biosynthetic process Source: Ensembl
  2. cholesterol catabolic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 39, subfamily a, polypeptide 1 (Predicted), isoform CRA_aImported
Submitted name:
Protein Cyp39a1Imported
Gene namesi
Name:Cyp39a1Imported
Synonyms:Cyp39a1_predictedImported
ORF Names:rCG_43541Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 9

Organism-specific databases

RGDi1307471. Cyp39a1.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074551.
KOiK07439.
OMAiDRWKEAN.
OrthoDBiEOG7W153H.
TreeFamiTF105090.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002403. Cyt_P450_E_grp-IV.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00465. EP450IV.
SUPFAMiSSF48264. SSF48264. 1 hit.

Sequencei

Sequence statusi: Complete.

D4AE09-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGIMELFSPI AIAVLGSCVL FLFSRWKNLR GPPCIQGWIP WIGAGFEFGK
60 70 80 90 100
APLEFIEKAR IKYGPVFTVF AVGKRMTFVT EEEGINVLLK SKHVDFELAV
110 120 130 140 150
QRPLYHTAWI PKNIFFALHE KLYVLMKGKM GTFNTHHFTG QLTEEFHDQL
160 170 180 190 200
EGLGTHGTMD LNDFVRYLLY PATLNTLFMK GLFLTDKRKI KEFYQHFKTY
210 220 230 240 250
DEGFEYGSQL PEWLLRNWSK SKRWLLALFE KNIGDIKTHG SAGHSETLLQ
260 270 280 290 300
AVLGMVETET RLHSPNYGLV MLWASLANAA PIAFWTLAYI LSHPDLHRTI
310 320 330 340 350
VESISSVFGT AGKDKIQVSE NDLKKLLLIK WCILESIRLR APGVITRKVV
360 370 380 390 400
KPVKILNHTV PSGDLLMLSP FWLHRNPKYF PEPESFKPER WKEANLDKYI
410 420 430 440 450
FLDYFMAFGG GKFQCPGRWF ALLEIQLCII LVLYKYECSL LDPLPKQAKF
460
SSFGGCPPAS REMPN
Length:465
Mass (Da):53,339
Last modified:April 20, 2010 - v1
Checksum:i09B7E3BA9FA8C41E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06058914 Genomic DNA. No translation available.
AABR06058915 Genomic DNA. No translation available.
AABR06058916 Genomic DNA. No translation available.
AABR06058917 Genomic DNA. No translation available.
AABR06058918 Genomic DNA. No translation available.
CH473987 Genomic DNA. Translation: EDM18705.1.
RefSeqiNP_001100363.1. NM_001106893.1.
UniGeneiRn.153360.

Genome annotation databases

EnsembliENSRNOT00000014051; ENSRNOP00000014051; ENSRNOG00000010519.
GeneIDi301264.
KEGGirno:301264.
UCSCiRGD:1307471. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06058914 Genomic DNA. No translation available.
AABR06058915 Genomic DNA. No translation available.
AABR06058916 Genomic DNA. No translation available.
AABR06058917 Genomic DNA. No translation available.
AABR06058918 Genomic DNA. No translation available.
CH473987 Genomic DNA. Translation: EDM18705.1 .
RefSeqi NP_001100363.1. NM_001106893.1.
UniGenei Rn.153360.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000014051 ; ENSRNOP00000014051 ; ENSRNOG00000010519 .
GeneIDi 301264.
KEGGi rno:301264.
UCSCi RGD:1307471. rat.

Organism-specific databases

CTDi 51302.
RGDi 1307471. Cyp39a1.

Phylogenomic databases

GeneTreei ENSGT00550000074551.
KOi K07439.
OMAi DRWKEAN.
OrthoDBi EOG7W153H.
TreeFami TF105090.

Miscellaneous databases

NextBioi 648423.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
IPR002403. Cyt_P450_E_grp-IV.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
PRINTSi PR00465. EP450IV.
SUPFAMi SSF48264. SSF48264. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4AE09_RAT
AccessioniPrimary (citable) accession number: D4AE09
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 1, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3