Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cytochrome P450, family 39, subfamily a, polypeptide 1

Gene

Cyp39a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

hemeUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi415Iron (heme axial ligand)UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-RNO-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
R-RNO-211976 Endogenous sterols

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 39, subfamily a, polypeptide 1Imported
Submitted name:
Cytochrome P450, family 39, subfamily a, polypeptide 1 (Predicted), isoform CRA_aImported
Gene namesi
Name:Cyp39a1Imported
Synonyms:Cyp39a1_predictedImported
ORF Names:rCG_43541Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 9

Organism-specific databases

RGDi1307471 Cyp39a1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, MembraneUniRule annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiD4AE09
PRIDEiD4AE09

Expressioni

Gene expression databases

BgeeiENSRNOG00000010519

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014051

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0684 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00550000074551
KOiK07439
OMAiIKWCILE
OrthoDBiEOG091G07L3
TreeFamiTF105090

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR024204 Cyt_P450_CYP7A1-type
IPR002403 Cyt_P450_E_grp-IV
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PIRSFiPIRSF000047 Cytochrome_CYPVIIA1, 1 hit
PRINTSiPR00465 EP450IV
SUPFAMiSSF48264 SSF48264, 1 hit

Sequencei

Sequence statusi: Complete.

D4AE09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIMELFSPI AIAVLGSCVL FLFSRWKNLR GPPCIQGWIP WIGAGFEFGK
60 70 80 90 100
APLEFIEKAR IKYGPVFTVF AVGKRMTFVT EEEGINVLLK SKHVDFELAV
110 120 130 140 150
QRPLYHTAWI PKNIFFALHE KLYVLMKGKM GTFNTHHFTG QLTEEFHDQL
160 170 180 190 200
EGLGTHGTMD LNDFVRYLLY PATLNTLFMK GLFLTDKRKI KEFYQHFKTY
210 220 230 240 250
DEGFEYGSQL PEWLLRNWSK SKRWLLALFE KNIGDIKTHG SAGHSETLLQ
260 270 280 290 300
AVLGMVETET RLHSPNYGLV MLWASLANAA PIAFWTLAYI LSHPDLHRTI
310 320 330 340 350
VESISSVFGT AGKDKIQVSE NDLKKLLLIK WCILESIRLR APGVITRKVV
360 370 380 390 400
KPVKILNHTV PSGDLLMLSP FWLHRNPKYF PEPESFKPER WKEANLDKYI
410 420 430 440 450
FLDYFMAFGG GKFQCPGRWF ALLEIQLCII LVLYKYECSL LDPLPKQAKF
460
SSFGGCPPAS REMPN
Length:465
Mass (Da):53,339
Last modified:April 20, 2010 - v1
Checksum:i09B7E3BA9FA8C41E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07066865 Genomic DNA No translation available.
AABR07066866 Genomic DNA No translation available.
CH473987 Genomic DNA Translation: EDM18705.1
RefSeqiNP_001100363.1, NM_001106893.1
UniGeneiRn.153360

Genome annotation databases

EnsembliENSRNOT00000014051; ENSRNOP00000014051; ENSRNOG00000010519
GeneIDi301264
KEGGirno:301264
UCSCiRGD:1307471 rat

Similar proteinsi

Entry informationi

Entry nameiD4AE09_RAT
AccessioniPrimary (citable) accession number: D4AE09
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health