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D4AE09

- D4AE09_RAT

UniProt

D4AE09 - D4AE09_RAT

Protein
Submitted name:

Cytochrome P450, family 39, subfamily a, polypeptide 1 (Predicted), isoform CRA_a

Gene

Cyp39a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. oxysterol 7-alpha-hydroxylase activity Source: Ensembl
    4. steroid 7-alpha-hydroxylase activity Source: Ensembl

    GO - Biological processi

    1. bile acid biosynthetic process Source: Ensembl
    2. cholesterol catabolic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cytochrome P450, family 39, subfamily a, polypeptide 1 (Predicted), isoform CRA_aImported
    Submitted name:
    Protein Cyp39a1Imported
    Gene namesi
    Name:Cyp39a1Imported
    Synonyms:Cyp39a1_predictedImported
    ORF Names:rCG_43541Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 9

    Organism-specific databases

    RGDi1307471. Cyp39a1.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00550000074551.
    KOiK07439.
    OMAiDRWKEAN.
    OrthoDBiEOG7W153H.
    TreeFamiTF105090.

    Family and domain databases

    Gene3Di1.10.630.10. 1 hit.
    InterProiIPR001128. Cyt_P450.
    IPR002403. Cyt_P450_E_grp-IV.
    [Graphical view]
    PfamiPF00067. p450. 1 hit.
    [Graphical view]
    PRINTSiPR00465. EP450IV.
    SUPFAMiSSF48264. SSF48264. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D4AE09-1 [UniParc]FASTAAdd to Basket

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    MGIMELFSPI AIAVLGSCVL FLFSRWKNLR GPPCIQGWIP WIGAGFEFGK    50
    APLEFIEKAR IKYGPVFTVF AVGKRMTFVT EEEGINVLLK SKHVDFELAV 100
    QRPLYHTAWI PKNIFFALHE KLYVLMKGKM GTFNTHHFTG QLTEEFHDQL 150
    EGLGTHGTMD LNDFVRYLLY PATLNTLFMK GLFLTDKRKI KEFYQHFKTY 200
    DEGFEYGSQL PEWLLRNWSK SKRWLLALFE KNIGDIKTHG SAGHSETLLQ 250
    AVLGMVETET RLHSPNYGLV MLWASLANAA PIAFWTLAYI LSHPDLHRTI 300
    VESISSVFGT AGKDKIQVSE NDLKKLLLIK WCILESIRLR APGVITRKVV 350
    KPVKILNHTV PSGDLLMLSP FWLHRNPKYF PEPESFKPER WKEANLDKYI 400
    FLDYFMAFGG GKFQCPGRWF ALLEIQLCII LVLYKYECSL LDPLPKQAKF 450
    SSFGGCPPAS REMPN 465
    Length:465
    Mass (Da):53,339
    Last modified:April 20, 2010 - v1
    Checksum:i09B7E3BA9FA8C41E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06058914 Genomic DNA. No translation available.
    AABR06058915 Genomic DNA. No translation available.
    AABR06058916 Genomic DNA. No translation available.
    AABR06058917 Genomic DNA. No translation available.
    AABR06058918 Genomic DNA. No translation available.
    CH473987 Genomic DNA. Translation: EDM18705.1.
    RefSeqiNP_001100363.1. NM_001106893.1.
    UniGeneiRn.153360.

    Genome annotation databases

    EnsembliENSRNOT00000014051; ENSRNOP00000014051; ENSRNOG00000010519.
    GeneIDi301264.
    KEGGirno:301264.
    UCSCiRGD:1307471. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06058914 Genomic DNA. No translation available.
    AABR06058915 Genomic DNA. No translation available.
    AABR06058916 Genomic DNA. No translation available.
    AABR06058917 Genomic DNA. No translation available.
    AABR06058918 Genomic DNA. No translation available.
    CH473987 Genomic DNA. Translation: EDM18705.1 .
    RefSeqi NP_001100363.1. NM_001106893.1.
    UniGenei Rn.153360.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000014051 ; ENSRNOP00000014051 ; ENSRNOG00000010519 .
    GeneIDi 301264.
    KEGGi rno:301264.
    UCSCi RGD:1307471. rat.

    Organism-specific databases

    CTDi 51302.
    RGDi 1307471. Cyp39a1.

    Phylogenomic databases

    GeneTreei ENSGT00550000074551.
    KOi K07439.
    OMAi DRWKEAN.
    OrthoDBi EOG7W153H.
    TreeFami TF105090.

    Miscellaneous databases

    NextBioi 648423.

    Family and domain databases

    Gene3Di 1.10.630.10. 1 hit.
    InterProi IPR001128. Cyt_P450.
    IPR002403. Cyt_P450_E_grp-IV.
    [Graphical view ]
    Pfami PF00067. p450. 1 hit.
    [Graphical view ]
    PRINTSi PR00465. EP450IV.
    SUPFAMi SSF48264. SSF48264. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD4AE09_RAT
    AccessioniPrimary (citable) accession number: D4AE09
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3