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D4ADM6 (D4ADM6_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length529 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Sequence similarities

Belongs to the alkaline phosphatase family. RuleBase RU003946

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSRNOP00000026095

Ontologies

Keywords
   LigandMagnesium RuleBase RU003947
Zinc RuleBase RU003947
   Molecular functionHydrolase RuleBase RU003947
   PTMPhosphoprotein RuleBase RU003947
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentmyofibril

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionalkaline phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D4ADM6 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 8D145B54479A178B

FASTA52957,253
        10         20         30         40         50         60 
MWGACLLLLG LSLQMSLSLV PVEEENPAFW NRKAAEALEA AKKLQPIQTS ANNLIILMGD 

        70         80         90        100        110        120 
GMGVSTVTAT RILKGQQQGH LGPETPLAMD RFPHMALSKT YNTDKQVPDS AGTGTAFLCG 

       130        140        150        160        170        180 
VKTNMKVIGL SAAARFNQCN TTWGNEVVSV MHRAKKAGKS VGVVTTTSVQ HASPAGTYAH 

       190        200        210        220        230        240 
TVNRNWYSDA HMSTAALQEG CKDIAMQLIS NTDIDVILGG GRKFMFPKGT PDQEYPTDPQ 

       250        260        270        280        290        300 
QAGTRLDGRN LVQEWLAKHQ GAQYVWNRTE LIQASLNRSV THLMGLFEPN DMKYNIDRDP 

       310        320        330        340        350        360 
TQDPSLAEMT EVAVHMLSRN PKGFYLFVEG GRIDHGHHEA IAYRALTEAV MFDSAVDKAD 

       370        380        390        400        410        420 
KLTSEKDTMI IVTADHSHVF SFGGYTQREA SIFGLAPFKA GDGKSFTSIL YGNGPGYKLN 

       430        440        450        460        470        480 
NGIRADVTEE ESSNPTYQQQ AAVPLSSETH SGEDVAIFAR GPQAHLVHGV QEQNYIAHVM 

       490        500        510        520 
AFAGCLEPYT DCGLAPPAGR SSAVSPGYIS TLLCLLAGTM LMLMVSAEP 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000026095.
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000026095.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABR06061444 Genomic DNA. No translation available.
RefSeqXP_002727285.1. XM_002727239.1.
XP_002730104.1. XM_002730058.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000025978; ENSRNOP00000026095; ENSRNOG00000033672.
GeneID100359675.
KEGGrno:100359675.
UCSCRGD:2325055. rat.

Organism-specific databases

CTD250.
RGD2325055. Alpp.

Phylogenomic databases

GeneTreeENSGT00390000008704.
KOK01077.
OMAKTNMKVI.
OrthoDBEOG7SN8CH.
PhylomeDBD4ADM6.
TreeFamTF323513.

Family and domain databases

Gene3D3.40.720.10. 1 hit.
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR001952. Alkaline_phosphatase.
IPR018299. Alkaline_phosphatase_AS.
IPR017850. Alkaline_phosphatase_core.
[Graphical view]
PfamPF00245. Alk_phosphatase. 1 hit.
[Graphical view]
PRINTSPR00113. ALKPHPHTASE.
SMARTSM00098. alkPPc. 1 hit.
[Graphical view]
SUPFAMSSF53649. SSF53649. 1 hit.
PROSITEPS00123. ALKALINE_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio34064933.
PROD4ADM6.

Entry information

Entry nameD4ADM6_RAT
AccessionPrimary (citable) accession number: D4ADM6
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 9, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)