D4ACX5 (D4ACX5_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GCN5 general control of amino acid synthesis-like 2 (Yeast) (Predicted) EMBL EDM06059.1

Submitted name:
Protein Kat2a Ensembl ENSRNOP00000052125

Gene names

Name:	Kat2a RGD 1307242 Ensembl ENSRNOP00000052125
Synonyms:	Gcn5l2_predicted EMBL EDM06059.1
ORF Names:	rCG_33366 EMBL EDM06059.1

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000052125

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	832 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Domain	Bromodomain SAAS SAAS018359
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell proliferation Inferred from electronic annotation. Source: Compara histone H3-K14 acetylation Inferred from electronic annotation. Source: Compara histone deubiquitination Inferred from electronic annotation. Source: Compara in utero embryonic development Inferred from electronic annotation. Source: Compara metencephalon development Inferred from electronic annotation. Source: Compara midbrain development Inferred from electronic annotation. Source: Compara multicellular organism growth Inferred from electronic annotation. Source: Compara neural tube closure Inferred from electronic annotation. Source: Compara regulation of apoptotic process Inferred from electronic annotation. Source: Compara regulation of protein stability Inferred from electronic annotation. Source: Compara regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro somitogenesis Inferred from electronic annotation. Source: Compara telencephalon development Inferred from electronic annotation. Source: Compara
Cellular_component	Ada2/Gcn5/Ada3 transcription activator complex Inferred from electronic annotation. Source: Compara STAGA complex Inferred from electronic annotation. Source: Compara mitotic spindle Inferred from electronic annotation. Source: Compara transcription factor TFTC complex Inferred from electronic annotation. Source: Compara
Molecular_function	H3 histone acetyltransferase activity Inferred from electronic annotation. Source: Compara chromatin binding Inferred from electronic annotation. Source: Compara histone acetyltransferase activity (H4-K12 specific) Inferred from electronic annotation. Source: Compara transcription coactivator activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D4ACX5 [UniParc]. Last modified April 3, 2013. Version 2. Checksum: EB9E3009F4BCE81B	FASTA	832	93,651
	10 20 30 40 50 60 MAEPSQAPNP APAAQPRPLQ SPAPAPTSTP APSPASAPTP APTPAPAPAP AAAPAGSTGT 70 80 90 100 110 120 GGAGVGSGGD PARPGLSQQQ RASQRKAQVR GLPRAKKLEK LGVFSACKAN ETCKCNGWKN 130 140 150 160 170 180 PKPPTAPRMD LQQPAANLSE LCRSCEHPLA DHVSHLENVS EDEINRLLGM VVDVENLFMS 190 200 210 220 230 240 VHKEEDTDTK QVYFYLFKLL RKCILQMTRP VVEGSLGSPP FEKPNIEQGV LNFVQYKFSH 250 260 270 280 290 300 LAPRERQTMF ELSKMFLLCL NYWKLETPAQ FRQRSQSEDV ATYKVNYTRW LCYCHVPQSC 310 320 330 340 350 360 DSLPRYETTH VFGRSLLRSI FTVTRRQLLE KFRVEKDKLV PEKRTLILTH FPKFLSMLEE 370 380 390 400 410 420 EIYGANSPIW ESGFTMPPSE GTQLVPRPAT VSATVVPSTP IFSPSMGGGS NSSLSLDSTG 430 440 450 460 470 480 TEPMPGEKRK LPENLTLEDA KRLRVMGDIP MELVNEVMLT ITDPAAMLGP ETSLLSANAA 490 500 510 520 530 540 RDETARLEER RGIIEFHVIG NSLTPKANRR VLLWLVGLQN VFSHQLPRMP KEYIARLVFD 550 560 570 580 590 600 PKHKTLALIK DGRVIGGICF RMFPTQGFTE IVFCAVTSNE QVKGYGTHLM NHLKEYHIKH 610 620 630 640 650 660 SILYFLTYAD EYAIGYFKKQ GFSKDIKVPK SRYLGYIKDY EGATLMECEL NPRIPYTELS 670 680 690 700 710 720 HIIKKQKEII KKLIERKQAQ IRKVYPGLSC FKEGVRQIPV ESVPGIRETG WKPLGKEKGK 730 740 750 760 770 780 ELKDPDQLYT TLKNLLAQIK SHPSAWPFME PVKKSEAPDY YEVIRFPIDL KTMTERLRSR 790 800 810 820 830 YYVTRKLFVA DLQRVIANCR EYNPPDSEYC RCASALEKFF YFKLKEGGLI DK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000052125.
[2]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDM06059.1.
[3]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDM06059.1.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000052125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06065574 Genomic DNA. No translation available. CH473948 Genomic DNA. Translation: EDM06059.1.
IPI	IPI00780430.
RefSeq	NP_001100520.1. NM_001107050.1.
UniGene	Rn.53502.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000055250; ENSRNOP00000052125; ENSRNOG00000018364.
GeneID	303539.
UCSC	RGD:1307242. rat.
Organism-specific databases
RGD	1307242. Kat2a.
Phylogenomic databases
GeneTree	ENSGT00660000095339.
OMA	GENSPIW.
OrthoDB	EOG4F1X2G.
Family and domain databases
Gene3D	1.20.920.10. 1 hit. 3.40.630.30. 1 hit.
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR001487. Bromodomain. IPR018359. Bromodomain_CS. IPR000182. GNAT_dom. IPR016376. Hist_acetylase_PCAF. IPR009464. PCAF_N. [Graphical view]
Pfam	PF13508. Acetyltransf_7. 1 hit. PF00439. Bromodomain. 1 hit. PF06466. PCAF_N. 1 hit. [Graphical view]
PIRSF	PIRSF003048. Histone_acetylase_PCAF. 1 hit.
PRINTS	PR00503. BROMODOMAIN.
SMART	SM00297. BROMO. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit. SSF47370. Bromodomain. 1 hit.
PROSITE	PS00633. BROMODOMAIN_1. 1 hit. PS50014. BROMODOMAIN_2. 1 hit. PS51186. GNAT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35574302.

Entry information

Entry name

D4ACX5_RAT

Accession

Primary (citable) accession number: D4ACX5

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 3, 2013
Last modified:	May 29, 2013
This is version 28 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)