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Protein
Submitted name:

GCN5 general control of amino acid synthesis-like 2 (Yeast) (Predicted)

Gene

Kat2a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei570Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-5250924 B-WICH complex positively regulates rRNA expression
R-RNO-5689880 Ub-specific processing proteases
R-RNO-8941856 RUNX3 regulates NOTCH signaling

Names & Taxonomyi

Protein namesi
Submitted name:
GCN5 general control of amino acid synthesis-like 2 (Yeast) (Predicted)Imported
Submitted name:
Lysine acetyltransferase 2AImported
Gene namesi
Name:Kat2aImported
Synonyms:Gcn5l2_predictedImported
ORF Names:rCG_33366Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1307242 Kat2a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiD4ACX5

Expressioni

Gene expression databases

BgeeiENSRNOG00000018364

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000052125

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini498 – 651N-acetyltransferaseInterPro annotationAdd BLAST154
Domaini740 – 810BromoInterPro annotationAdd BLAST71

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni574 – 576Acetyl-CoA bindingUniRule annotation3
Regioni581 – 587Acetyl-CoA bindingUniRule annotation7
Regioni612 – 615Acetyl-CoA bindingUniRule annotation4

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili663 – 683Sequence analysisAdd BLAST21

Keywords - Domaini

BromodomainPROSITE-ProRule annotationSAAS annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1472 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00760000119099
KOiK06062
OMAiNHLKDYS
OrthoDBiEOG091G03ZO
TreeFamiTF105399

Family and domain databases

Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR037800 GCN5
IPR016376 GCN5/PCAF
IPR000182 GNAT_dom
IPR009464 PCAF_N
PANTHERiPTHR22880:SF124 PTHR22880:SF124, 1 hit
PfamiView protein in Pfam
PF00583 Acetyltransf_1, 1 hit
PF00439 Bromodomain, 1 hit
PF06466 PCAF_N, 1 hit
PIRSFiPIRSF003048 Histone_acetylase_PCAF, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF55729 SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS51186 GNAT, 1 hit

Sequencei

Sequence statusi: Complete.

D4ACX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEPSQAPNP APAAQPRPLQ SPAPAPTSTP APSPASAPTP APTPAPAPAP
60 70 80 90 100
AAAPAGSTGT GGAGVGSGGD PARPGLSQQQ RASQRKAQVR GLPRAKKLEK
110 120 130 140 150
LGVFSACKAN ETCKCNGWKN PKPPTAPRMD LQQPAANLSE LCRSCEHPLA
160 170 180 190 200
DHVSHLENVS EDEINRLLGM VVDVENLFMS VHKEEDTDTK QVYFYLFKLL
210 220 230 240 250
RKCILQMTRP VVEGSLGSPP FEKPNIEQGV LNFVQYKFSH LAPRERQTMF
260 270 280 290 300
ELSKMFLLCL NYWKLETPAQ FRQRSQSEDV ATYKVNYTRW LCYCHVPQSC
310 320 330 340 350
DSLPRYETTH VFGRSLLRSI FTVTRRQLLE KFRVEKDKLV PEKRTLILTH
360 370 380 390 400
FPKFLSMLEE EIYGANSPIW ESGFTMPPSE GTQLVPRPAT VSATVVPSTP
410 420 430 440 450
IFSPSMGGGS NSSLSLDSTG TEPMPGEKRK LPENLTLEDA KRLRVMGDIP
460 470 480 490 500
MELVNEVMLT ITDPAAMLGP ETSLLSANAA RDETARLEER RGIIEFHVIG
510 520 530 540 550
NSLTPKANRR VLLWLVGLQN VFSHQLPRMP KEYIARLVFD PKHKTLALIK
560 570 580 590 600
DGRVIGGICF RMFPTQGFTE IVFCAVTSNE QVKGYGTHLM NHLKEYHIKH
610 620 630 640 650
SILYFLTYAD EYAIGYFKKQ GFSKDIKVPK SRYLGYIKDY EGATLMECEL
660 670 680 690 700
NPRIPYTELS HIIKKQKEII KKLIERKQAQ IRKVYPGLSC FKEGVRQIPV
710 720 730 740 750
ESVPGIRETG WKPLGKEKGK ELKDPDQLYT TLKNLLAQIK SHPSAWPFME
760 770 780 790 800
PVKKSEAPDY YEVIRFPIDL KTMTERLRSR YYVTRKLFVA DLQRVIANCR
810 820 830
EYNPPDSEYC RCASALEKFF YFKLKEGGLI DK
Length:832
Mass (Da):93,651
Last modified:April 3, 2013 - v2
Checksum:iEB9E3009F4BCE81B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030475 Genomic DNA No translation available.
CH473948 Genomic DNA Translation: EDM06059.1
RefSeqiNP_001100520.1, NM_001107050.1
UniGeneiRn.53502

Genome annotation databases

EnsembliENSRNOT00000055250; ENSRNOP00000052125; ENSRNOG00000018364
GeneIDi303539
KEGGirno:303539
UCSCiRGD:1307242 rat

Similar proteinsi

Entry informationi

Entry nameiD4ACX5_RAT
AccessioniPrimary (citable) accession number: D4ACX5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: April 25, 2018
This is version 70 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health