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D4ACI9

- D4ACI9_RAT

UniProt

D4ACI9 - D4ACI9_RAT

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Protein
Submitted name:

Intraflagellar transport 88 homolog (Chlamydomonas) (Predicted)

Gene

Ift88

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. anterior/posterior pattern specification Source: Ensembl
  2. cardiac muscle cell differentiation Source: Ensembl
  3. cardiac septum morphogenesis Source: Ensembl
  4. cochlea development Source: Ensembl
  5. cytoplasmic microtubule organization Source: Ensembl
  6. determination of left/right symmetry Source: Ensembl
  7. embryonic digit morphogenesis Source: Ensembl
  8. epidermal stem cell homeostasis Source: Ensembl
  9. epidermis development Source: Ensembl
  10. epithelial cell morphogenesis Source: Ensembl
  11. eye development Source: Ensembl
  12. forebrain morphogenesis Source: Ensembl
  13. heart formation Source: Ensembl
  14. inner ear receptor stereocilium organization Source: Ensembl
  15. kidney development Source: Ensembl
  16. liver development Source: Ensembl
  17. lung vasculature development Source: Ensembl
  18. negative regulation of epithelial cell proliferation Source: Ensembl
  19. Notch signaling pathway Source: Ensembl
  20. palate development Source: Ensembl
  21. pancreas development Source: Ensembl
  22. positive regulation of insulin-like growth factor receptor signaling pathway Source: Ensembl
  23. protein localization Source: Ensembl
  24. regulation of autophagic vacuole assembly Source: Ensembl
  25. regulation of cilium assembly Source: Ensembl
  26. regulation of fat cell differentiation Source: Ensembl
  27. regulation of odontogenesis of dentin-containing tooth Source: Ensembl
  28. regulation of protein processing Source: Ensembl
  29. regulation of smoothened signaling pathway Source: Ensembl
  30. response to fluid shear stress Source: Ensembl
  31. smoothened signaling pathway Source: Ensembl
  32. spermatid nucleus elongation Source: Ensembl
  33. sperm axoneme assembly Source: Ensembl
  34. spinal cord dorsal/ventral patterning Source: Ensembl
  35. telencephalon development Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intraflagellar transport 88 homolog (Chlamydomonas) (Predicted)Imported
Submitted name:
Protein Ift88Imported
Gene namesi
Name:Ift88Imported
Synonyms:Ift88_predictedImported
ORF Names:rCG_23607Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 15

Organism-specific databases

RGDi1309717. Ift88.

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: Ensembl
  2. axonemal basal plate Source: Ensembl
  3. centriole Source: Ensembl
  4. ciliary basal body Source: Ensembl
  5. ciliary base Source: Ensembl
  6. ciliary tip Source: Ensembl
  7. intraciliary transport particle B Source: Ensembl
  8. kinocilium Source: Ensembl
  9. motile cilium Source: UniProtKB-KW
  10. motile primary cilium Source: Ensembl
  11. outer acrosomal membrane Source: MGI
  12. photoreceptor connecting cilium Source: Ensembl
  13. trans-Golgi network Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell projection, Cilium, FlagellumImported

Family & Domainsi

Keywords - Domaini

RepeatUniRule annotation, TPR repeatUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000015473.
KOiK16474.
OMAiLILCYYA.
OrthoDBiEOG7N37D5.
TreeFamiTF313218.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
InterProiIPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF00515. TPR_1. 1 hit.
PF13174. TPR_6. 1 hit.
[Graphical view]
SMARTiSM00028. TPR. 7 hits.
[Graphical view]
PROSITEiPS50005. TPR. 10 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4ACI9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMENVHLAPE TDEDDLYSGF NDYNPAYDTE ELENDTGFQQ AVRTSHGRRP
60 70 80 90 100
PVTAKIPSTA VSRPIATGYG SKTSLTSSMG RPMTGTIQDG VARPMTAVRA
110 120 130 140 150
AGFSKAALRG SAFDPLGQSR GPAPPLEAKN EDSPEEKIRQ LEKKVNELVE
160 170 180 190 200
ESCIANSCGD LKLALEKAKD AGRKERVLVR QREQVTSPEN INLDLTYSVL
210 220 230 240 250
FNLASQYSAN EMYAEALNTY QVIVKNKMFS NAGRLKVNMG NIYLKQRNYS
260 270 280 290 300
KAIKFYRMAL DQIPSVHKEM RIKIMQNIGI TFIKTGQYSD AINSFEHIMS
310 320 330 340 350
MAPSLKAGFN LILSCFAIGD REKMKKAFQK LIAVPLEIDE DDKYISPSDD
360 370 380 390 400
PHTNLLIEAI KNDHLRQMER ERKAMAEKYI MTAAKLIAPV IEASFAVGYN
410 420 430 440 450
WCVEVVKASQ YVELANDLEI NKAITYLRQK DFNQAVDTLK MFEKKDSRVK
460 470 480 490 500
SAAATNLSFL YYLENEFAQA SSYADLAVSS DRYNPSALTN KGNTVFANGD
510 520 530 540 550
YEKAAEFYKE ALRNDSSCTE ALYNIGLTYK KLNRLDEALD SFLKLHAILR
560 570 580 590 600
NSAQVLCQIA NVYELMEDPN QAIEWLMQLI SVVPTDSQAL SKLGELYDSE
610 620 630 640 650
GDKSQAFQYY YESYRYFPSN IEVIEWLGAY YIDTQFCEKA IQYFERASLI
660 670 680 690 700
QPTQVKWQLM VASCFRRSGN YQKALDTYKE IHRKFPENVE CLRFLVRLCT
710 720 730 740 750
DIGLKEVQEY ATKLKRLEKM KEMREQRIKS GRDSGGGSRS KREGSAGSDS
760 770 780 790 800
GQNSSASSKS ERLSAKLRAL PGTDEPYESS GNKEIGKCLL CGSTGPSDRK
810
TKNCSQKENR RGRFC
Length:815
Mass (Da):91,885
Last modified:April 20, 2010 - v1
Checksum:i938EE721F5179A01
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06083433 Genomic DNA. No translation available.
AABR06083434 Genomic DNA. No translation available.
CH474049 Genomic DNA. Translation: EDM14349.1.
RefSeqiNP_001100736.1. NM_001107266.1.
UniGeneiRn.132110.

Genome annotation databases

EnsembliENSRNOT00000012988; ENSRNOP00000012988; ENSRNOG00000009278.
GeneIDi305918.
KEGGirno:305918.
UCSCiRGD:1309717. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06083433 Genomic DNA. No translation available.
AABR06083434 Genomic DNA. No translation available.
CH474049 Genomic DNA. Translation: EDM14349.1 .
RefSeqi NP_001100736.1. NM_001107266.1.
UniGenei Rn.132110.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000012988 ; ENSRNOP00000012988 ; ENSRNOG00000009278 .
GeneIDi 305918.
KEGGi rno:305918.
UCSCi RGD:1309717. rat.

Organism-specific databases

CTDi 8100.
RGDi 1309717. Ift88.

Phylogenomic databases

GeneTreei ENSGT00390000015473.
KOi K16474.
OMAi LILCYYA.
OrthoDBi EOG7N37D5.
TreeFami TF313218.

Miscellaneous databases

NextBioi 655246.

Family and domain databases

Gene3Di 1.25.40.10. 4 hits.
InterProi IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view ]
Pfami PF00515. TPR_1. 1 hit.
PF13174. TPR_6. 1 hit.
[Graphical view ]
SMARTi SM00028. TPR. 7 hits.
[Graphical view ]
PROSITEi PS50005. TPR. 10 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4ACI9_RAT
AccessioniPrimary (citable) accession number: D4ACI9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3