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Protein
Submitted name:

Protein Zfp703

Gene

Zfp703

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. nucleic acid binding Source: InterPro

GO - Biological processi

  1. adherens junction assembly Source: Ensembl
  2. cellular response to estradiol stimulus Source: Ensembl
  3. mammary gland epithelial cell differentiation Source: Ensembl
  4. negative regulation of homotypic cell-cell adhesion Source: Ensembl
  5. negative regulation of transcription, DNA-templated Source: Ensembl
  6. positive regulation of cell migration Source: Ensembl
  7. positive regulation of epithelial to mesenchymal transition Source: Ensembl
  8. positive regulation of mammary gland epithelial cell proliferation Source: Ensembl
  9. regulation of canonical Wnt signaling pathway Source: Ensembl
  10. regulation of cell cycle Source: Ensembl
  11. regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Zfp703Imported
Submitted name:
RCG43251Imported
Gene namesi
Name:Zfp703Imported
ORF Names:rCG_43251Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1588249. Zfp703.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nuclear matrix Source: Ensembl
  3. protein complex Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000014618.
OMAiCPPFPPH.
OrthoDBiEOG7WDN2N.
TreeFamiTF324968.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR022129. Tscrpt_rep_NocA-like.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF12402. nlz1. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4ABF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSPAGSNP RTPESSGSGG SGGGGKRPAV PAVVSLLPPA DPLRQANRLP
60 70 80 90 100
IRVLKMLSAH TGHLLHPEYL QPLSSTPVSP IELDAKKSPL ALLAQTCSQI
110 120 130 140 150
GKPDPPPSSK LNSVAAAAAN GLGSEKDPSR SAPGAASAAA ALKQLGDSPA
160 170 180 190 200
EDKSSFKPYS KGSGGGDSRK DGGSSSVSST TSSSSSSPGD KAGFRVPSAA
210 220 230 240 250
CPPFPPHGAA VSTSSNSSSP GGSRGGSPHH SDCKSGSGGA GGGGELDKKD
260 270 280 290 300
QEAKPSPEPA AGSRGSSGDS AHGGPEATAS GRKSEPPSAL VGAGHVAPVS
310 320 330 340 350
PYKPGHSVFP LPPSSIGYHG SIVGAYAGYP SQFVPGLDPS KSGLVGGQLS
360 370 380 390 400
GGLGLPPGKP PSSSPLTGAS PPSFLQGLCR DPYCLGGYHS ASHLGGSSCS
410 420 430 440 450
TCSAHDPAGP SLKASGYPLV YPGHPLQPAA LSSSAAQAAL PGHPLYTYGF
460 470 480 490 500
MLQNEPLPHS CNWVAASGPC DKRFATSEEL LSHLRTHTAL PGAEKLLAAY
510 520 530 540 550
PGASSLGSAA AAAAAAASCH LHLPPPAAPG SPGSLSLRSP HTLGLSRYHP
560 570 580 590
YGKSHLSTAG GLAVPSLPTA GPYYSPYALY GQRLASASAL GYQ
Length:593
Mass (Da):58,556
Last modified:April 20, 2010 - v1
Checksum:i9A02BABFB9D6C228
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06088953 Genomic DNA. No translation available.
CH473970 Genomic DNA. Translation: EDM09087.1.
RefSeqiNP_001102895.1. NM_001109425.1.
UniGeneiRn.15384.

Genome annotation databases

EnsembliENSRNOT00000019002; ENSRNOP00000019001; ENSRNOG00000014199.
GeneIDi680717.
KEGGirno:680717.
UCSCiRGD:1588249. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06088953 Genomic DNA. No translation available.
CH473970 Genomic DNA. Translation: EDM09087.1.
RefSeqiNP_001102895.1. NM_001109425.1.
UniGeneiRn.15384.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019002; ENSRNOP00000019001; ENSRNOG00000014199.
GeneIDi680717.
KEGGirno:680717.
UCSCiRGD:1588249. rat.

Organism-specific databases

CTDi353310.
RGDi1588249. Zfp703.

Phylogenomic databases

GeneTreeiENSGT00390000014618.
OMAiCPPFPPH.
OrthoDBiEOG7WDN2N.
TreeFamiTF324968.

Miscellaneous databases

NextBioi719347.

Family and domain databases

Gene3Di3.30.160.60. 1 hit.
InterProiIPR022129. Tscrpt_rep_NocA-like.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF12402. nlz1. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS50157. ZINC_FINGER_C2H2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4ABF5_RAT
AccessioniPrimary (citable) accession number: D4ABF5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 29, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.