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D4ABC2

- D4ABC2_RAT

UniProt

D4ABC2 - D4ABC2_RAT

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Protein
Submitted name:

Protein Dnajb2

Gene

Dnajb2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. ER-associated ubiquitin-dependent protein catabolic process Source: Ensembl
  2. negative regulation of cell growth Source: Ensembl
  3. negative regulation of cell proliferation Source: Ensembl
  4. negative regulation of inclusion body assembly Source: Ensembl
  5. negative regulation of protein deubiquitination Source: Ensembl
  6. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  7. positive regulation of protein ubiquitination Source: Ensembl
  8. protein refolding Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Dnajb2Imported
Submitted name:
RCG23817, isoform CRA_eImported
Gene namesi
Name:Dnajb2Imported
ORF Names:rCG_23817Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 9

Organism-specific databases

RGDi1591035. Dnajb2.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. inclusion body Source: Ensembl
  3. nucleus Source: Ensembl
  4. proteasome complex Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118947.
KOiK09508.
OMAiRGPRHSG.
OrthoDBiEOG7KSX9F.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR003903. Ubiquitin-int_motif.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
SM00726. UIM. 2 hits.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
PS50330. UIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4ABC2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASYYEILDV PRSASPDDIK KAYRKKALQW HPDKNPDNKE FAEKKFKEVA
60 70 80 90 100
EAYEVLSDRS GPSRSETGGM EPGFTFTFRS PEEVFREFFG SGDPFSELFD
110 120 130 140 150
DLGAFSELQN QGSRLTGPFF TFSSSFPGNS DFSSSSFSFS PGAGAFRSVS
160 170 180 190 200
TSTTFVQGRR ITTRRIMENG QERVEVEEDG QLKSVSINGV PDDLALGLEL
210 220 230 240 250
SRREQQPSVT PGLGVMQVRP TSVSRPPDSD LSEDEDMQLA MAYSLSEMEA

SGQKPADVF
Length:259
Mass (Da):28,663
Last modified:April 20, 2010 - v1
Checksum:i80B98CF14C202D81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06061115 Genomic DNA. No translation available.
CH474004 Genomic DNA. Translation: EDL75414.1.
RefSeqiNP_001103011.1. NM_001109541.1.
UniGeneiRn.40780.

Genome annotation databases

EnsembliENSRNOT00000026467; ENSRNOP00000026467; ENSRNOG00000019506.
GeneIDi689593.
KEGGirno:689593.
UCSCiRGD:1591035. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06061115 Genomic DNA. No translation available.
CH474004 Genomic DNA. Translation: EDL75414.1 .
RefSeqi NP_001103011.1. NM_001109541.1.
UniGenei Rn.40780.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000026467 ; ENSRNOP00000026467 ; ENSRNOG00000019506 .
GeneIDi 689593.
KEGGi rno:689593.
UCSCi RGD:1591035. rat.

Organism-specific databases

CTDi 3300.
RGDi 1591035. Dnajb2.

Phylogenomic databases

GeneTreei ENSGT00760000118947.
KOi K09508.
OMAi RGPRHSG.
OrthoDBi EOG7KSX9F.

Miscellaneous databases

NextBioi 739000.

Family and domain databases

Gene3Di 1.10.287.110. 1 hit.
InterProi IPR001623. DnaJ_domain.
IPR003903. Ubiquitin-int_motif.
[Graphical view ]
Pfami PF00226. DnaJ. 1 hit.
[Graphical view ]
PRINTSi PR00625. JDOMAIN.
SMARTi SM00271. DnaJ. 1 hit.
SM00726. UIM. 2 hits.
[Graphical view ]
SUPFAMi SSF46565. SSF46565. 1 hit.
PROSITEi PS50076. DNAJ_2. 1 hit.
PS50330. UIM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4ABC2_RAT
AccessioniPrimary (citable) accession number: D4ABC2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3