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D4ABC2

- D4ABC2_RAT

UniProt

D4ABC2 - D4ABC2_RAT

Protein
Submitted name:

Protein Dnajb2

Gene

Dnajb2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. ER-associated ubiquitin-dependent protein catabolic process Source: Ensembl
    2. negative regulation of cell growth Source: Ensembl
    3. negative regulation of cell proliferation Source: Ensembl
    4. negative regulation of inclusion body assembly Source: Ensembl
    5. negative regulation of protein deubiquitination Source: Ensembl
    6. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
    7. positive regulation of protein ubiquitination Source: Ensembl

    Keywords - Molecular functioni

    ChaperoneUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Dnajb2Imported
    Submitted name:
    RCG23817, isoform CRA_eImported
    Gene namesi
    Name:Dnajb2Imported
    ORF Names:rCG_23817Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 9

    Organism-specific databases

    RGDi1591035. Dnajb2.

    Subcellular locationi

    GO - Cellular componenti

    1. inclusion body Source: Ensembl
    2. proteasome complex Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00730000110396.
    KOiK09508.
    OMAiRGPRHSG.
    OrthoDBiEOG7KSX9F.

    Family and domain databases

    Gene3Di1.10.287.110. 1 hit.
    InterProiIPR001623. DnaJ_domain.
    IPR003903. Ubiquitin-int_motif.
    [Graphical view]
    PfamiPF00226. DnaJ. 1 hit.
    [Graphical view]
    PRINTSiPR00625. JDOMAIN.
    SMARTiSM00271. DnaJ. 1 hit.
    SM00726. UIM. 2 hits.
    [Graphical view]
    SUPFAMiSSF46565. SSF46565. 1 hit.
    PROSITEiPS50076. DNAJ_2. 1 hit.
    PS50330. UIM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D4ABC2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASYYEILDV PRSASPDDIK KAYRKKALQW HPDKNPDNKE FAEKKFKEVA    50
    EAYEVLSDRS GPSRSETGGM EPGFTFTFRS PEEVFREFFG SGDPFSELFD 100
    DLGAFSELQN QGSRLTGPFF TFSSSFPGNS DFSSSSFSFS PGAGAFRSVS 150
    TSTTFVQGRR ITTRRIMENG QERVEVEEDG QLKSVSINGV PDDLALGLEL 200
    SRREQQPSVT PGLGVMQVRP TSVSRPPDSD LSEDEDMQLA MAYSLSEMEA 250
    SGQKPADVF 259
    Length:259
    Mass (Da):28,663
    Last modified:April 20, 2010 - v1
    Checksum:i80B98CF14C202D81
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06061115 Genomic DNA. No translation available.
    CH474004 Genomic DNA. Translation: EDL75414.1.
    RefSeqiNP_001103011.1. NM_001109541.1.
    UniGeneiRn.40780.

    Genome annotation databases

    EnsembliENSRNOT00000026467; ENSRNOP00000026467; ENSRNOG00000019506.
    GeneIDi689593.
    KEGGirno:689593.
    UCSCiRGD:1591035. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06061115 Genomic DNA. No translation available.
    CH474004 Genomic DNA. Translation: EDL75414.1 .
    RefSeqi NP_001103011.1. NM_001109541.1.
    UniGenei Rn.40780.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000026467 ; ENSRNOP00000026467 ; ENSRNOG00000019506 .
    GeneIDi 689593.
    KEGGi rno:689593.
    UCSCi RGD:1591035. rat.

    Organism-specific databases

    CTDi 3300.
    RGDi 1591035. Dnajb2.

    Phylogenomic databases

    GeneTreei ENSGT00730000110396.
    KOi K09508.
    OMAi RGPRHSG.
    OrthoDBi EOG7KSX9F.

    Miscellaneous databases

    NextBioi 739000.

    Family and domain databases

    Gene3Di 1.10.287.110. 1 hit.
    InterProi IPR001623. DnaJ_domain.
    IPR003903. Ubiquitin-int_motif.
    [Graphical view ]
    Pfami PF00226. DnaJ. 1 hit.
    [Graphical view ]
    PRINTSi PR00625. JDOMAIN.
    SMARTi SM00271. DnaJ. 1 hit.
    SM00726. UIM. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46565. SSF46565. 1 hit.
    PROSITEi PS50076. DNAJ_2. 1 hit.
    PS50330. UIM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD4ABC2_RAT
    AccessioniPrimary (citable) accession number: D4ABC2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3