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D4AB17

- D4AB17_RAT

UniProt

D4AB17 - D4AB17_RAT

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Protein
Submitted name:

Protein LOC100912917

Gene

LOC100912917

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphoribosylformylglycinamidine synthase activity Source: InterPro

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: RGD
  3. response to drug Source: RGD
  4. ribonucleoside monophosphate biosynthetic process Source: RGD
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_217264. Purine ribonucleoside monophosphate biosynthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein LOC100912917Imported
Gene namesi
Name:LOC100912917Imported
Synonyms:PfasImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 10

Organism-specific databases

RGDi6485156. LOC100912917.
1304926. Pfas.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD4AB17.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000007600.
InParanoidiD4AB17.
OMAiPPKMSRI.
OrthoDBiEOG7353X4.
TreeFamiTF106371.

Family and domain databases

Gene3Di3.30.1330.10. 2 hits.
3.40.50.880. 1 hit.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF55326. SSF55326. 2 hits.
SSF56042. SSF56042. 2 hits.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4AB17-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMLLGSPGWS LAPMICCWRW DPGTLNFSTP ASTNIVSVCQ AAGLRAVDRV
60 70 80 90 100
ETTRRYRLSF AKQPTAEMEA ISLAALHDRM TEQHYPDPIQ SFSPQSIPAP
110 120 130 140 150
LKDSINILAE GRPALEKANQ ELGLALDSWD LDFYTKRFQE LQRNPSTVEV
160 170 180 190 200
FDLAQSNSEH SRHWFFKGQL HVDGKKLARS LFESIMSTQS SSNPNNVLKF
210 220 230 240 250
CDNSSAIQGK EVRFLRPEDS TRPSCFRQQR GLRHVVFTAE THNFPTGVAP
260 270 280 290 300
FSGATTGTGG RIRDVQCTGR GAHVVAGTAG YCFGNLHIPG YNLPWEDPSF
310 320 330 340 350
QYPGNFARPL EVAIEASNGA SDYGNKFGEP VLAGFARSLG LQLPDGQRRE
360 370 380 390 400
WIKPIMFSGG IGSMEAKHVG KEPPEPGMEV VKVGGPVYRI GVGGGAASSV
410 420 430 440 450
QVQGDNTSDL DFGAVQRGDP EMEQKMNRVI RACVEAPGGN PICSLHDQGA
460 470 480 490 500
GGNGNVLKEL SEPAGAVIYT SRFQLGDPTL NALEIWGAEY QESNALLLRP
510 520 530 540 550
SDRDFLSRAS ARERCPACFV GTITGDKRIV LVDDRECLMG KSGQGDAPPT
560 570 580 590 600
PPTPVDLDLD WVLGKMPQKE FFLQRKPPVL QPLALPPDLS VGQALERVLR
610 620 630 640 650
LPAVASKRYL TNKVDRSVGG LVAQQQCVGP LQTPLADVAV VALSHQELVG
660 670 680 690 700
AATALGEQPV KSLLDPKAAA RLAVSEALTN LVFALVTDLR DVKCSGNWMW
710 720 730 740 750
AAKLPGEGAG LADACEAMVT VMAALGVAVD GGKDSLSMAA RVGTETVPAP
760 770 780 790 800
GSLVISAYAV CPDITATVTP DLKHPGGKGH LLYVPLSPGQ HRLGGTALAQ
810 820 830 840 850
CFSQLGEHPP DLDLPENLVR AFHITQGLLK GEWGPDRRLC SGHDVSDGGL
860 870 880 890 900
VTCLLEMAFA GNCGIEVDVP APGIHALPVL FAEEPGLVLE VQEADVAGVL
910 920 930 940 950
QRYQSAGLHC LELGHTGEAG PQAMVRVSVN GTVVVEEPVG QLRALWEETS
960 970 980 990 1000
FQLDLLQAEP RCVTEEKQGL KERIGPSYCL PPTFPVASVP CKPGGPIPRV
1010 1020 1030 1040 1050
AILREEGSNG DREMADAFHL AGFEVWDVTM QDLCSGAVRL DTFRGVAFVG
1060 1070 1080 1090 1100
GFSYADVLGS AKGWAAAVTF NPQAREELGR FRRRPDTFSL GVCNGCQLLA
1110 1120 1130 1140 1150
LLGWVGSDPN EDQVEPDHDS QPAQPGLLLR HNLSGRFESR WATVRVEPGP
1160 1170 1180 1190 1200
ALMLRGMEGS VLPVWSAHGE GYMAFSSPEL QAKIKAKGLV PLHWADDDGN
1210 1220 1230 1240 1250
PTEQYPLNPN GSPGGIAGIC SPDGRHLALM PHPERAVRLW QWAWRPSPFD
1260 1270
GLSTSPWLQL FINARNWTQE DSC
Length:1,273
Mass (Da):137,053
Last modified:April 3, 2013 - v2
Checksum:i74FA1E59482C1D6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06064370 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000007087; ENSRNOP00000007087; ENSRNOG00000005193.
UCSCiRGD:1304926. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR06064370 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi D4AB17.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000007087 ; ENSRNOP00000007087 ; ENSRNOG00000005193 .
UCSCi RGD:1304926. rat.

Organism-specific databases

RGDi 6485156. LOC100912917.
1304926. Pfas.

Phylogenomic databases

GeneTreei ENSGT00390000007600.
InParanoidi D4AB17.
OMAi PPKMSRI.
OrthoDBi EOG7353X4.
TreeFami TF106371.

Enzyme and pathway databases

Reactomei REACT_217264. Purine ribonucleoside monophosphate biosynthesis.

Miscellaneous databases

NextBioi 35573916.

Family and domain databases

Gene3Di 3.30.1330.10. 2 hits.
3.40.50.880. 1 hit.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 2 hits.
[Graphical view ]
SUPFAMi SSF52317. SSF52317. 1 hit.
SSF55326. SSF55326. 2 hits.
SSF56042. SSF56042. 2 hits.
TIGRFAMsi TIGR01735. FGAM_synt. 1 hit.
PROSITEi PS51273. GATASE_TYPE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4AB17_RAT
AccessioniPrimary (citable) accession number: D4AB17
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: November 26, 2014
This is version 40 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3