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Protein
Submitted name:

Protein LOC100912917

Gene

LOC100912917

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • 'de novo' IMP biosynthetic process Source: InterPro
  • glutamine metabolic process Source: RGD
  • purine nucleotide biosynthetic process Source: GO_Central
  • response to drug Source: RGD
  • ribonucleoside monophosphate biosynthetic process Source: RGD
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_352908. Purine ribonucleoside monophosphate biosynthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein LOC100912917Imported
Gene namesi
Name:LOC100912917Imported
Synonyms:PfasImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi6485156. LOC100912917.
1304926. Pfas.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiD4AB17.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007087.

Family & Domainsi

Phylogenomic databases

InParanoidiD4AB17.
OMAiSLSANWM.
OrthoDBiEOG7353X4.
TreeFamiTF106371.

Family and domain databases

Gene3Di3.30.1330.10. 2 hits.
3.40.50.880. 1 hit.
HAMAPiMF_00419. PurL_1.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF55326. SSF55326. 2 hits.
SSF56042. SSF56042. 2 hits.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4AB17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLLGSPGWS LAPMICCWRW DPLNFSTPAS TNIVSVCQAA GLRAVDRVET
60 70 80 90 100
TRRYRLSFAK QPTAEMEAIS LAALHDRMTE QHYPDPIQSF SPQSIPAPLK
110 120 130 140 150
DSINILAEGR PALEKANQEL GLALDSWDLD FYTKRFQELQ RNPSTVEVFD
160 170 180 190 200
LAQSNSEHSR HWFFKGQLHV DGKKLARSLF ESIMSTQSSS NPNNVLKFCD
210 220 230 240 250
NSSAIQGKEV RFLRPEDSTR PSCFRQQRGL RHVVFTAETH NFPTGVAPFS
260 270 280 290 300
GATTGTGGRI RDVQCTGRGA HVVAGTAGYC FGNLHIPGYN LPWEDPSFQY
310 320 330 340 350
PGNFARPLEV AIEASNGASD YGNKFGEPVL AGFARSLGLQ LPDGQRREWI
360 370 380 390 400
KPIMFSGGIG SMEAKHVGKE PPEPGMEVVK VGGPVYRIGV GGGAASSVQV
410 420 430 440 450
QGDNTSDLDF GAVQRGDPEM EQKMNRVIRA CVEAPGGNPI CSLHDQGAGG
460 470 480 490 500
NGNVLKELSE PAGAVIYTSR FQLGDPTLNA LEIWGAEYQE SNALLLRPSD
510 520 530 540 550
RDFLSRASAR ERCPACFVGT ITGDKRIVLV DDRECLMGKS GQGDAPPTPP
560 570 580 590 600
TPVDLDLDWV LGKMPQKEFF LQRKPPVLQP LALPPDLSVG QALERVLRLP
610 620 630 640 650
AVASKRYLTN KVDRSVGGLV AQQQCVGPLQ TPLADVAVVA LSHQELVGAA
660 670 680 690 700
TALGEQPVKS LLDPKAAARL AVSEALTNLV FALVTDLRDV KCSGNWMWAA
710 720 730 740 750
KLPGEGAGLA DACEAMVTVM AALGVAVDGG KDSLSMAARV GTETVPAPGS
760 770 780 790 800
LVISAYAVCP DITATVTPDL KHPGGKGHLL YVPLSPGQHR LGGTALAQCF
810 820 830 840 850
SQLGEHPPDL DLPENLVRAF HITQGLLKGE WGPDRRLCSG HDVSDGGLVT
860 870 880 890 900
CLLEMAFAGN CGIEVDVPAP GIHALPVLFA EEPGLVLEVQ EADVAGVLQR
910 920 930 940 950
YQSAGLHCLE LGHTGEAGPQ AMVRVSVNGT VVVEEPVGQL RALWEETSFQ
960 970 980 990 1000
LDLLQAEPRC VTEEKQGLKE RIGPSYCLPP TFPVASVPCK PGGPIPRVAI
1010 1020 1030 1040 1050
LREEGSNGDR EMADAFHLAG FEVWDVTMQD LCSGAVRLDT FRGVAFVGGF
1060 1070 1080 1090 1100
SYADVLGSAK GWAAAVTFNP QAREELGRFR RRPDTFSLGV CNGCQLLALL
1110 1120 1130 1140 1150
GWVGSDPNED QVEPDHDSQP AQPGLLLRHN LSGRFESRWA TVRVEPGPAL
1160 1170 1180 1190 1200
MLRGMEGSVL PVWSAHGEGY MAFSSPELQA KIKAKGLVPL HWADDDGNPT
1210 1220 1230 1240 1250
EQYPLNPNGS PGGIAGICSP DGRHLALMPH PERAVRLWQW AWRPSPFDGL
1260 1270
STSPWLQLFI NARNWTQEDS C
Length:1,271
Mass (Da):136,894
Last modified:July 22, 2015 - v3
Checksum:i3557F7FFE9F02DA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126877 Genomic DNA. No translation available.
AC129753 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000007087; ENSRNOP00000007087; ENSRNOG00000005193.
UCSCiRGD:1304926. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126877 Genomic DNA. No translation available.
AC129753 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007087.

Proteomic databases

PRIDEiD4AB17.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000007087; ENSRNOP00000007087; ENSRNOG00000005193.
UCSCiRGD:1304926. rat.

Organism-specific databases

RGDi6485156. LOC100912917.
1304926. Pfas.

Phylogenomic databases

InParanoidiD4AB17.
OMAiSLSANWM.
OrthoDBiEOG7353X4.
TreeFamiTF106371.

Enzyme and pathway databases

ReactomeiREACT_352908. Purine ribonucleoside monophosphate biosynthesis.

Miscellaneous databases

NextBioi35573916.

Family and domain databases

Gene3Di3.30.1330.10. 2 hits.
3.40.50.880. 1 hit.
HAMAPiMF_00419. PurL_1.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF55326. SSF55326. 2 hits.
SSF56042. SSF56042. 2 hits.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.
  3. "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiD4AB17_RAT
AccessioniPrimary (citable) accession number: D4AB17
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: July 22, 2015
This is version 48 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.