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D4AB17

- D4AB17_RAT

UniProt

D4AB17 - D4AB17_RAT

Protein
Submitted name:

Protein LOC100912917

Gene

LOC100912917

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 2 (03 Apr 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. phosphoribosylformylglycinamidine synthase activity Source: InterPro

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: InterPro
    2. glutamine metabolic process Source: RGD
    3. response to drug Source: RGD
    4. ribonucleoside monophosphate biosynthetic process Source: RGD

    Enzyme and pathway databases

    ReactomeiREACT_217264. Purine ribonucleoside monophosphate biosynthesis.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein LOC100912917Imported
    Gene namesi
    Name:LOC100912917Imported
    Synonyms:PfasImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 10

    Organism-specific databases

    RGDi6485156. LOC100912917.
    1304926. Pfas.

    PTM / Processingi

    Proteomic databases

    PRIDEiD4AB17.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000007600.
    OMAiPPKMSRI.
    OrthoDBiEOG7353X4.
    TreeFamiTF106371.

    Family and domain databases

    Gene3Di3.30.1330.10. 2 hits.
    3.40.50.880. 1 hit.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR029062. Class_I_gatase-like.
    IPR017926. GATASE.
    IPR010073. PRibForGlyAmidine_synth.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 2 hits.
    [Graphical view]
    SUPFAMiSSF52317. SSF52317. 1 hit.
    SSF55326. SSF55326. 2 hits.
    SSF56042. SSF56042. 2 hits.
    TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
    PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D4AB17-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMLLGSPGWS LAPMICCWRW DPGTLNFSTP ASTNIVSVCQ AAGLRAVDRV     50
    ETTRRYRLSF AKQPTAEMEA ISLAALHDRM TEQHYPDPIQ SFSPQSIPAP 100
    LKDSINILAE GRPALEKANQ ELGLALDSWD LDFYTKRFQE LQRNPSTVEV 150
    FDLAQSNSEH SRHWFFKGQL HVDGKKLARS LFESIMSTQS SSNPNNVLKF 200
    CDNSSAIQGK EVRFLRPEDS TRPSCFRQQR GLRHVVFTAE THNFPTGVAP 250
    FSGATTGTGG RIRDVQCTGR GAHVVAGTAG YCFGNLHIPG YNLPWEDPSF 300
    QYPGNFARPL EVAIEASNGA SDYGNKFGEP VLAGFARSLG LQLPDGQRRE 350
    WIKPIMFSGG IGSMEAKHVG KEPPEPGMEV VKVGGPVYRI GVGGGAASSV 400
    QVQGDNTSDL DFGAVQRGDP EMEQKMNRVI RACVEAPGGN PICSLHDQGA 450
    GGNGNVLKEL SEPAGAVIYT SRFQLGDPTL NALEIWGAEY QESNALLLRP 500
    SDRDFLSRAS ARERCPACFV GTITGDKRIV LVDDRECLMG KSGQGDAPPT 550
    PPTPVDLDLD WVLGKMPQKE FFLQRKPPVL QPLALPPDLS VGQALERVLR 600
    LPAVASKRYL TNKVDRSVGG LVAQQQCVGP LQTPLADVAV VALSHQELVG 650
    AATALGEQPV KSLLDPKAAA RLAVSEALTN LVFALVTDLR DVKCSGNWMW 700
    AAKLPGEGAG LADACEAMVT VMAALGVAVD GGKDSLSMAA RVGTETVPAP 750
    GSLVISAYAV CPDITATVTP DLKHPGGKGH LLYVPLSPGQ HRLGGTALAQ 800
    CFSQLGEHPP DLDLPENLVR AFHITQGLLK GEWGPDRRLC SGHDVSDGGL 850
    VTCLLEMAFA GNCGIEVDVP APGIHALPVL FAEEPGLVLE VQEADVAGVL 900
    QRYQSAGLHC LELGHTGEAG PQAMVRVSVN GTVVVEEPVG QLRALWEETS 950
    FQLDLLQAEP RCVTEEKQGL KERIGPSYCL PPTFPVASVP CKPGGPIPRV 1000
    AILREEGSNG DREMADAFHL AGFEVWDVTM QDLCSGAVRL DTFRGVAFVG 1050
    GFSYADVLGS AKGWAAAVTF NPQAREELGR FRRRPDTFSL GVCNGCQLLA 1100
    LLGWVGSDPN EDQVEPDHDS QPAQPGLLLR HNLSGRFESR WATVRVEPGP 1150
    ALMLRGMEGS VLPVWSAHGE GYMAFSSPEL QAKIKAKGLV PLHWADDDGN 1200
    PTEQYPLNPN GSPGGIAGIC SPDGRHLALM PHPERAVRLW QWAWRPSPFD 1250
    GLSTSPWLQL FINARNWTQE DSC 1273
    Length:1,273
    Mass (Da):137,053
    Last modified:April 3, 2013 - v2
    Checksum:i74FA1E59482C1D6F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06064370 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSRNOT00000007087; ENSRNOP00000007087; ENSRNOG00000005193.
    UCSCiRGD:1304926. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06064370 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi D4AB17.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000007087 ; ENSRNOP00000007087 ; ENSRNOG00000005193 .
    UCSCi RGD:1304926. rat.

    Organism-specific databases

    RGDi 6485156. LOC100912917.
    1304926. Pfas.

    Phylogenomic databases

    GeneTreei ENSGT00390000007600.
    OMAi PPKMSRI.
    OrthoDBi EOG7353X4.
    TreeFami TF106371.

    Enzyme and pathway databases

    Reactomei REACT_217264. Purine ribonucleoside monophosphate biosynthesis.

    Miscellaneous databases

    NextBioi 35573916.

    Family and domain databases

    Gene3Di 3.30.1330.10. 2 hits.
    3.40.50.880. 1 hit.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR029062. Class_I_gatase-like.
    IPR017926. GATASE.
    IPR010073. PRibForGlyAmidine_synth.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52317. SSF52317. 1 hit.
    SSF55326. SSF55326. 2 hits.
    SSF56042. SSF56042. 2 hits.
    TIGRFAMsi TIGR01735. FGAM_synt. 1 hit.
    PROSITEi PS51273. GATASE_TYPE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD4AB17_RAT
    AccessioniPrimary (citable) accession number: D4AB17
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 3, 2013
    Last modified: October 1, 2014
    This is version 38 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3