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D4AAI2 (D4AAI2_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Protein Hmha1 Ensembl ENSRNOP00000057381
Gene names
Name:Hmha1 Ensembl ENSRNOP00000057381 RGD 1308662
Synonyms:Hmha1_predicted EMBL EDL89354.1
ORF Names:rCG_29286 EMBL EDL89354.1
OrganismRattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000057381
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length1116 AA.
Sequence statusComplete.
Protein existencePredicted

Ontologies

Keywords
   LigandMetal-binding SAAS SAAS002219
Zinc SAAS SAAS002219
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processintracellular signal transduction

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D4AAI2 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 8B1D750485D88901

FASTA1,116123,077
        10         20         30         40         50         60 
MFSRKKRELM KTPSISKKNR AGSPNPQSSS GELPRKDCTE TPSLEPPAMS LSTVAKGTGT 

        70         80         90        100        110        120 
LKRPTSLSRH ASAAGFPLSG TATRTLGRGY RSPLSAASPA ELPTEGPFPD GVEDISTLLA 

       130        140        150        160        170        180 
DVARFAEGLE KLKEFVLRDD LLEARRPLAH ECLGEALRVM RQVISKYPLL NTVETLTAAG 

       190        200        210        220        230        240 
TLIAKVKAFH YECNNESDKR EFEKALETIA VSFSCTVSEF LLGEVDSSTL LAVPPGDPSQ 

       250        260        270        280        290        300 
LVENLYGSGS EGPPHSVEDC EEGCLPPEEV DMLLQRCEGG VDAALQYAKD MARYMKDLIG 

       310        320        330        340        350        360 
YLEKRTTLEM EFAKGLQKVV HNCRQNVTHA PHMPLLSIYS LALEQDLEFG HGMVQAVGTL 

       370        380        390        400        410        420 
QTQTFMQPLT LRRLEHERRR KEIKESWHRA QRKLQEAEAN LRKAKQGYKQ RCEDHDKARL 

       430        440        450        460        470        480 
QVAKAEEEQQ GTGPGAGTAA SKALDKRRRL EEEAKNKAEE AMATYRTCVA DAKTQKQELE 

       490        500        510        520        530        540 
DTKVTALRQI QEVIRQSDQT IKSATISYYQ LMHMQTAPLP VNFQMLCESS KLYDPGQQYA 

       550        560        570        580        590        600 
SHVRQLQRGE EPDVRYDFEP YVSTNAWSPI MRTRKGSFNP GDASGPEAAG SPPEEGGTSE 

       610        620        630        640        650        660 
GAPNKDHRGG RGHQVHKSWP ISISDTEVSL DVSSGDLKKF DRTSSSGTMS SNEELVDQEA 

       670        680        690        700        710        720 
GLVASAFDSA DLNGMDPELP VAMPSGPFRH VGLSKAARTH RLRKLRTPAK CRECNSYVYF 

       730        740        750        760        770        780 
QGAECEECCL ACHKKCLETL AIQCGHKKLQ GRLQLFGQDF SQAAHSTPDG VPFIIKKCVC 

       790        800        810        820        830        840 
EIERRALHTK GIYRVNGVKT RVEKLCQAFE NGKELVELSQ ASPHDISNVL KLYLRQLPEP 

       850        860        870        880        890        900 
LISFRFYHEL VGLAKDSLKA EAEAKAASRG RQDGSESEAA TLAMVGRLRE LMRDLPAENR 

       910        920        930        940        950        960 
ATLLYLLRHL RRIVEMEQDN KMTPGNLGIV FGPTLLRPRP TDATVSLSSL VDYPHQARVI 

       970        980        990       1000       1010       1020 
ETLIVHYGLV FEEEPEEAAG SQEGASAQCA QLETAEGIVF PQQEEADDGN RESQVASNDS 

      1030       1040       1050       1060       1070       1080 
DSELEEASDL LSSSDASALH RLSFLEQTEA GLEEGPQSHS GSEEQLESED AAPGHQLCSF 

      1090       1100       1110 
NTNQSNNTTQ ASLPTMRLRD GQITGGSGRK RQPQFV 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000057381.
[2]"Gene and alternative splicing annotation with AIR."
Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G.
Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL EDL89354.1.
[3]Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. expand/collapse author list , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BN EMBL EDL89354.1.
[4]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000057381.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABR06047719 Genomic DNA. No translation available.
AABR06047720 Genomic DNA. No translation available.
AABR06047721 Genomic DNA. No translation available.
CH474029 Genomic DNA. Translation: EDL89354.1.
RefSeqNP_001101537.1. NM_001108067.1.
UniGeneRn.35286.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000060648; ENSRNOP00000057381; ENSRNOG00000013220.
GeneID314618.
KEGGrno:314618.
UCSCRGD:1308662. rat.

Organism-specific databases

CTD23526.
RGD1308662. Hmha1.

Phylogenomic databases

GeneTreeENSGT00740000115398.
OMALMRPRPT.
OrthoDBEOG7QNVK4.
PhylomeDBD4AAI2.
TreeFamTF351450.

Family and domain databases

Gene3D1.10.555.10. 1 hit.
InterProIPR001060. FCH_dom.
IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTSM00109. C1. 1 hit.
SM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMSSF48350. SSF48350. 1 hit.
PROSITEPS50238. RHOGAP. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio667925.
PROD4AAI2.

Entry information

Entry nameD4AAI2_RAT
AccessionPrimary (citable) accession number: D4AAI2
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 9, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)