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Protein
Submitted name:

Histocompatibility (Minor) HA-1 (Predicted), isoform CRA_b

Gene

Hmha1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-bindingSAAS annotation, ZincSAAS annotation

Enzyme and pathway databases

ReactomeiR-RNO-194840. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Submitted name:
Histocompatibility (Minor) HA-1 (Predicted), isoform CRA_bImported
Submitted name:
Protein Hmha1Imported
Gene namesi
Name:Hmha1Imported
Synonyms:Hmha1_predictedImported
ORF Names:rCG_29286Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1308662. Hmha1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

PTM databases

PhosphoSiteiD4AAI2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000013220.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057381.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini268 – 538271F-BARInterPro annotationAdd
BLAST
Domaini699 – 74446Phorbol-ester/DAG-typeInterPro annotationAdd
BLAST
Domaini758 – 971214Rho-GAPInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili380 – 40728Sequence analysisAdd
BLAST
Coiled coili440 – 46425Sequence analysisAdd
BLAST
Coiled coili469 – 49628Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains F-BAR domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1453. Eukaryota.
ENOG410YM3I. LUCA.
GeneTreeiENSGT00840000129703.
OMAiGMVQAVG.
OrthoDBiEOG091G00SA.
TreeFamiTF351450.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR031160. F_BAR.
IPR001060. FCH_dom.
IPR002219. PE/DAG-bd.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS51741. F_BAR. 1 hit.
PS50238. RHOGAP. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4AAI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSRKKRELM KTPSISKKNR AGSPNPQSSS GELPRKDCTE TPSLEPPAMS
60 70 80 90 100
LSTVAKGTGT LKRPTSLSRH ASAAGFPLSG TATRTLGRGY RSPLSAASPA
110 120 130 140 150
ELPTEGPFPD GVEDISTLLA DVARFAEGLE KLKEFVLRDD LLEARRPLAH
160 170 180 190 200
ECLGEALRVM RQVISKYPLL NTVETLTAAG TLIAKVKAFH YECNNESDKR
210 220 230 240 250
EFEKALETIA VSFSCTVSEF LLGEVDSSTL LAVPPGDPSQ LVENLYGSGS
260 270 280 290 300
EGPPHSVEDC EEGCLPPEEV DMLLQRCEGG VDAALQYAKD MARYMKDLIG
310 320 330 340 350
YLEKRTTLEM EFAKGLQKVV HNCRQNVTHA PHMPLLSIYS LALEQDLEFG
360 370 380 390 400
HGMVQAVGTL QTQTFMQPLT LRRLEHERRR KEIKESWHRA QRKLQEAEAN
410 420 430 440 450
LRKAKQGYKQ RCEDHDKARL QVAKAEEEQQ GTGPGAGTAA SKALDKRRRL
460 470 480 490 500
EEEAKNKAEE AMATYRTCVA DAKTQKQELE DTKVTALRQI QEVIRQSDQT
510 520 530 540 550
IKSATISYYQ LMHMQTAPLP VNFQMLCESS KLYDPGQQYA SHVRQLQRGE
560 570 580 590 600
EPDVRYDFEP YVSTNAWSPI MRTRKGSFNP GDASGPEAAG SPPEEGGTSE
610 620 630 640 650
GAPNKDHRGG RGHQVHKSWP ISISDTEVSL DVSSGDLKKF DRTSSSGTMS
660 670 680 690 700
SNEELVDQEA GLVASAFDSA DLNGMDPELP VAMPSGPFRH VGLSKAARTH
710 720 730 740 750
RLRKLRTPAK CRECNSYVYF QGAECEECCL ACHKKCLETL AIQCGHKKLQ
760 770 780 790 800
GRLQLFGQDF SQAAHSTPDG VPFIIKKCVC EIERRALHTK GIYRVNGVKT
810 820 830 840 850
RVEKLCQAFE NGKELVELSQ ASPHDISNVL KLYLRQLPEP LISFRFYHEL
860 870 880 890 900
VGLAKDSLKA EAEAKAASRG RQDGSESEAA TLAMVGRLRE LMRDLPAENR
910 920 930 940 950
ATLLYLLRHL RRIVEMEQDN KMTPGNLGIV FGPTLLRPRP TDATVSLSSL
960 970 980 990 1000
VDYPHQARVI ETLIVHYGLV FEEEPEEAAG SQEGASAQCA QLETAEGIVF
1010 1020 1030 1040 1050
PQQEEADDGN RESQVASNDS DSELEEASDL LSSSDASALH RLSFLEQTEA
1060 1070 1080 1090 1100
GLEEGPQSHS GSEEQLESED AAPGHQLCSF NTNQSNNTTQ ASLPTMRLRD
1110
GQITGGSGRK RQPQFV
Length:1,116
Mass (Da):123,077
Last modified:April 20, 2010 - v1
Checksum:i8B1D750485D88901
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07055842 Genomic DNA. No translation available.
AABR07055843 Genomic DNA. No translation available.
AABR07055844 Genomic DNA. No translation available.
AABR07055845 Genomic DNA. No translation available.
AABR07055846 Genomic DNA. No translation available.
AABR07055847 Genomic DNA. No translation available.
AABR07055848 Genomic DNA. No translation available.
AABR07073280 Genomic DNA. No translation available.
CH474029 Genomic DNA. Translation: EDL89354.1.
RefSeqiNP_001101537.1. NM_001108067.1.
UniGeneiRn.35286.

Genome annotation databases

EnsembliENSRNOT00000060648; ENSRNOP00000057381; ENSRNOG00000013220.
GeneIDi314618.
KEGGirno:314618.
UCSCiRGD:1308662. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07055842 Genomic DNA. No translation available.
AABR07055843 Genomic DNA. No translation available.
AABR07055844 Genomic DNA. No translation available.
AABR07055845 Genomic DNA. No translation available.
AABR07055846 Genomic DNA. No translation available.
AABR07055847 Genomic DNA. No translation available.
AABR07055848 Genomic DNA. No translation available.
AABR07073280 Genomic DNA. No translation available.
CH474029 Genomic DNA. Translation: EDL89354.1.
RefSeqiNP_001101537.1. NM_001108067.1.
UniGeneiRn.35286.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057381.

PTM databases

PhosphoSiteiD4AAI2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000060648; ENSRNOP00000057381; ENSRNOG00000013220.
GeneIDi314618.
KEGGirno:314618.
UCSCiRGD:1308662. rat.

Organism-specific databases

CTDi23526.
RGDi1308662. Hmha1.

Phylogenomic databases

eggNOGiKOG1453. Eukaryota.
ENOG410YM3I. LUCA.
GeneTreeiENSGT00840000129703.
OMAiGMVQAVG.
OrthoDBiEOG091G00SA.
TreeFamiTF351450.

Enzyme and pathway databases

ReactomeiR-RNO-194840. Rho GTPase cycle.

Gene expression databases

BgeeiENSRNOG00000013220.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR031160. F_BAR.
IPR001060. FCH_dom.
IPR002219. PE/DAG-bd.
IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
[Graphical view]
SMARTiSM00109. C1. 1 hit.
SM00055. FCH. 1 hit.
SM00324. RhoGAP. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
PROSITEiPS51741. F_BAR. 1 hit.
PS50238. RHOGAP. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD4AAI2_RAT
AccessioniPrimary (citable) accession number: D4AAI2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 7, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.