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Protein
Submitted name:

Protease, serine, 22 (Predicted)

Gene

Prss22

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS01.252.

Names & Taxonomyi

Protein namesi
Submitted name:
Protease, serine, 22 (Predicted)Imported
Submitted name:
Protein Prss22Imported
Gene namesi
Name:Prss22Imported
Synonyms:Prss22_predictedImported
ORF Names:rCG_32556Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1310880. Prss22.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500816133133 – 307Sequence analysisAdd BLAST275

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiD4AAE4.

Expressioni

Gene expression databases

BgeeiENSRNOG00000039698.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057610.

Structurei

3D structure databases

ProteinModelPortaliD4AAE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 290Peptidase S1InterPro annotationAdd BLAST241

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation
Contains 1 peptidase S1 domain.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118810.
KOiK09626.
OMAiTNCWIAG.
OrthoDBiEOG091G0AH5.
PhylomeDBiD4AAE4.
TreeFamiTF351676.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiIPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4AAE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVISRPPLAL GGDQFRTLIL LVLLTSTATV SAANIRGSPD CGKPQQLNRV
60 70 80 90 100
VGGEDSADAQ WPWIVSILKN GSHHCAGSLL TNRWVVSAAH CFSSNMDKPS
110 120 130 140 150
PYSVLLGAWK LGNPGPRSQK VGIASVLPHP RYSRKEGTHA DIALVRLERP
160 170 180 190 200
IQFSERILPI CLPDSSVHLP PNTNCWIAGW GSIQDGVPLP RPQTLQKLKV
210 220 230 240 250
PIIDPELCKS LYWRGAGQEA ITEDMLCAGY LEGKRDACLG DSGGPLMCQV
260 270 280 290 300
DDHWLLTGII SWGEGCAERN RPGVYTSLLA HRPWVQRIVQ GVQLRGRLAD

SGDTGSS
Length:307
Mass (Da):33,286
Last modified:April 20, 2010 - v1
Checksum:iA0DE5E04439396D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130139 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM03800.1.
RefSeqiNP_001100454.1. NM_001106984.1.
UniGeneiRn.137172.

Genome annotation databases

EnsembliENSRNOT00000060888; ENSRNOP00000057610; ENSRNOG00000039698.
GeneIDi302971.
KEGGirno:302971.
UCSCiRGD:1310880. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130139 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM03800.1.
RefSeqiNP_001100454.1. NM_001106984.1.
UniGeneiRn.137172.

3D structure databases

ProteinModelPortaliD4AAE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057610.

Protein family/group databases

MEROPSiS01.252.

Proteomic databases

PeptideAtlasiD4AAE4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000060888; ENSRNOP00000057610; ENSRNOG00000039698.
GeneIDi302971.
KEGGirno:302971.
UCSCiRGD:1310880. rat.

Organism-specific databases

CTDi64063.
RGDi1310880. Prss22.

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118810.
KOiK09626.
OMAiTNCWIAG.
OrthoDBiEOG091G0AH5.
PhylomeDBiD4AAE4.
TreeFamiTF351676.

Gene expression databases

BgeeiENSRNOG00000039698.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiIPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiD4AAE4_RAT
AccessioniPrimary (citable) accession number: D4AAE4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 2, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.