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Protein
Submitted name:

Protease, serine, 22

Gene

Prss22

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS01.252.

Names & Taxonomyi

Protein namesi
Submitted name:
Protease, serine, 22Imported
Submitted name:
Protease, serine, 22 (Predicted)Imported
Gene namesi
Name:Prss22Imported
Synonyms:Prss22_predictedImported
ORF Names:rCG_32556Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1310880. Prss22.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_501082979133 – 307Sequence analysisAdd BLAST275

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000039698.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057610.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 290Peptidase S1InterPro annotationAdd BLAST241

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118810.
KOiK09626.
OMAiLTNRWVV.
OrthoDBiEOG091G0AH5.
TreeFamiTF351676.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
PfamiView protein in Pfam
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.

Sequencei

Sequence statusi: Complete.

D4AAE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVISRPPLAL GGDQFRTLIL LVLLTSTATV SAANIRGSPD CGKPQQLNRV
60 70 80 90 100
VGGEDSADAQ WPWIVSILKN GSHHCAGSLL TNRWVVSAAH CFSSNMDKPS
110 120 130 140 150
PYSVLLGAWK LGNPGPRSQK VGIASVLPHP RYSRKEGTHA DIALVRLERP
160 170 180 190 200
IQFSERILPI CLPDSSVHLP PNTNCWIAGW GSIQDGVPLP RPQTLQKLKV
210 220 230 240 250
PIIDPELCKS LYWRGAGQEA ITEDMLCAGY LEGKRDACLG DSGGPLMCQV
260 270 280 290 300
DDHWLLTGII SWGEGCAERN RPGVYTSLLA HRPWVQRIVQ GVQLRGRLAD

SGDTGSS
Length:307
Mass (Da):33,286
Last modified:April 20, 2010 - v1
Checksum:iA0DE5E04439396D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130139 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM03800.1.
RefSeqiNP_001100454.1. NM_001106984.1.
UniGeneiRn.137172.

Genome annotation databases

EnsembliENSRNOT00000060888; ENSRNOP00000057610; ENSRNOG00000039698.
GeneIDi302971.
KEGGirno:302971.
UCSCiRGD:1310880. rat.

Similar proteinsi

Entry informationi

Entry nameiD4AAE4_RAT
AccessioniPrimary (citable) accession number: D4AAE4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: August 30, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported