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Protein
Submitted name:

Kinesin family member 7

Gene

Kif7

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi94 – 101ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-5610787. Hedgehog 'off' state.
R-RNO-5632684. Hedgehog 'on' state.

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin family member 7Imported
Gene namesi
Name:Kif7Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1310310. Kif7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD4A9P0.
PeptideAtlasiD4A9P0.

PTM databases

iPTMnetiD4A9P0.
PhosphoSitePlusiD4A9P0.

Expressioni

Gene expression databases

BgeeiENSRNOG00000026857.
GenevisibleiD4A9P0. RN.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000038247.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 349Kinesin motorInterPro annotationAdd BLAST335

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili489 – 537Sequence analysisAdd BLAST49
Coiled coili729 – 756Sequence analysisAdd BLAST28
Coiled coili781 – 808Sequence analysisAdd BLAST28
Coiled coili812 – 881Sequence analysisAdd BLAST70
Coiled coili903 – 937Sequence analysisAdd BLAST35
Coiled coili962 – 989Sequence analysisAdd BLAST28
Coiled coili998 – 1025Sequence analysisAdd BLAST28
Coiled coili1174 – 1208Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0244. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00900000140824.
InParanoidiD4A9P0.
KOiK18806.
OMAiAMASEWR.
OrthoDBiEOG091G0156.
PhylomeDBiD4A9P0.
TreeFamiTF325946.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiView protein in InterPro
IPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR036961. Kinesin_motor_dom_sf.
IPR027417. P-loop_NTPase.
PANTHERiPTHR24115. PTHR24115. 2 hits.
PfamiView protein in Pfam
PF00225. Kinesin. 1 hit.
PRINTSiPR00380. KINESINHEAVY.
SMARTiView protein in SMART
SM00129. KISc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D4A9P0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLEAQKLSG AEEAPVRVAL RVRPLLPKEL LHGHQSCLQV EPERGRITLG
60 70 80 90 100
RDRHFGFHVV LGEDAGQEAV YQACVQPLLE AFFEGFNATV FAYGQTGSGK
110 120 130 140 150
TYTMGEASVA SLHEDEQGII PRAMAEAFKL IDENDLLDCL VHVSYLELYK
160 170 180 190 200
EEFRDLLEVG TASRDIQLRE DDRGNVVLCG VKEVDVEGLD EVLSLLEMGN
210 220 230 240 250
AARHTGATHF NRLSSRSHTV FTVTLEQRGR APTRLPRPGA GHLLVSKFHF
260 270 280 290 300
VDLAGSERVL KTGSTGERLK ESIQINSTLL ALGNVISALG DPQRRGSHIP
310 320 330 340 350
YRDSKITRIL KDSLGGNAKT VMIACVSPSS SDFDETLNTL NYASRAQNIR
360 370 380 390 400
NRATVNWRPE AERVPEEQAA GARGPPRHRS ETRIIHRGRR VLCPGVGSAA
410 420 430 440 450
VAPGLGTECA RCRARTSAAY SLLRELQAEP GLPGAAARKV RDWLCAVEGE
460 470 480 490 500
RSALSSASGP DSGIESAPAD DQAAQGTSGR KGDEGAQQLL ILQSQVARLE
510 520 530 540 550
EENRDFLAAL EDAMEQYKLQ SDRLREQQEE MVELRLRLEL AQPGWGAPGL
560 570 580 590 600
LQGLSPGSFV PRPHTAPLGG AHTHMTGTMP RTCLPGEEVS SEQQVANGKE
610 620 630 640 650
AKAELLAQVD KLGSASSTTS EEEEEEEEEP PRRTLHLRRN GISNWSQRAG
660 670 680 690 700
VRPGSPPDRK GPEVCPEEPA AAIPAPQAVG GSKAPGQTRQ APAAMASEWR
710 720 730 740 750
LAQAQQKIRE LAINIRMKEE LIGELVRTGK AAQALNRQHS QRIRELEQEA
760 770 780 790 800
ERVRGELCEG QRQLRELEGR EPQDASERSR LQEFRKRVAA AQSQVQVLRE
810 820 830 840 850
KKQATERLVS LSAQSETRLQ ELERNVQLMR RQQGQLQRRL REETEQKRRL
860 870 880 890 900
ETEMNKRQHR VKELELKHEQ QQKILKIKTE EIAAFQRNRR SGSNGSVVSL
910 920 930 940 950
EQQQKIEEQK KWLDQEMEKV LQQRRALEEL GEELRKREVI LAKKEALMQE
960 970 980 990 1000
KTGLESKRMR SSQALNEDIV RVSSRLEHLE KELSEKSGQL RQGSALNQQQ
1010 1020 1030 1040 1050
IRGEIDTLRQ EKDSLLKQRL EIDSKLRQGS LLSPEEERTL FQLDEAIEAL
1060 1070 1080 1090 1100
DAAIEYKNEA ITCRQRVLRA SASLLSQCEM NLMAKLSYLS SSETRALLCK
1110 1120 1130 1140 1150
YFDKVVTLRE EQHQQQIAFS ELEMQLEEQQ RLVYWLEVAL ERQRLEMDRQ
1160 1170 1180 1190 1200
LTLQQKEHEQ NVQLLLQQGR DHLGEGLADS KRQYEARIQA LEKELGRHMW
1210 1220 1230 1240 1250
INQELKQKLS AGNTAGQSRG CERRSHCLEN RQGLGNEDGP HVAAQEPLWP
1260 1270 1280 1290 1300
SSLLEGAPRV WDESRDLVHA PLPLTWKRSS LCSEQGSSEE PRARETTEPP
1310 1320 1330 1340
VGRVLPMGEV SLSWNFGPLP KPRWEPRRTS PGMIDVRKNP L
Length:1,341
Mass (Da):150,578
Last modified:April 20, 2010 - v1
Checksum:i1EC298BF441A64E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096024 Genomic DNA. No translation available.
RefSeqiXP_001065361.2. XM_001065361.6.
XP_218828.5. XM_218828.9.

Genome annotation databases

EnsembliENSRNOT00000033491; ENSRNOP00000038247; ENSRNOG00000026857.
GeneIDi293047.
KEGGirno:293047.
UCSCiRGD:1310310. rat.

Similar proteinsi

Entry informationi

Entry nameiD4A9P0_RAT
AccessioniPrimary (citable) accession number: D4A9P0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 25, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported