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Protein
Submitted name:

Protein Malt1

Gene

Malt1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_278187. FCERI mediated NF-kB activation.
REACT_318052. Activation of NF-kappaB in B cells.
REACT_342970. Downstream TCR signaling.
REACT_359556. CLEC7A (Dectin-1) signaling.
REACT_361089. CLEC7A/inflammasome pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Malt1Imported
Gene namesi
Name:Malt1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 18

Organism-specific databases

RGDi1309195. Malt1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiD4A980. baseline.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000059281.

Structurei

3D structure databases

ProteinModelPortaliD4A980.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiD4A980.
OMAiHPDNKEQ.
OrthoDBiEOG7673BH.
PhylomeDBiD4A980.
TreeFamiTF319744.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
2.60.40.10. 2 hits.
3.40.50.1460. 1 hit.
InterProiIPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003598. Ig_sub2.
IPR011600. Pept_C14_caspase.
IPR001309. Pept_C14_ICE_p20.
[Graphical view]
PfamiPF00656. Peptidase_C14. 1 hit.
[Graphical view]
SMARTiSM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50208. CASPASE_P20. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4A980-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEKGCTVPE LSDFLQALEH TEVLQLLNPP GLKITVNPES KAVLAGQFVK
60 70 80 90 100
LCCRATGHPF VQYQWFKMNK EIPYGNSSEL IFNTVHVKDA GFYVCRVNNN
110 120 130 140 150
STFEFSQWSQ LDVCDVTEVS DSFQGSLDGV SESKLRICVE PQSQKLAPGS
160 170 180 190 200
ALLLQCVAIG SPVPHYQWFK DESPLAHETK KHYTVPYVDL EHEGTYWCHV
210 220 230 240 250
YNDRDSQDSK KVEIIIGRTD GAVECTEDEL NNLGRPDNKE QTGQPLAKDK
260 270 280 290 300
VALLIGNMNY WEHPKLKAPL VDVYELTNLL RQLDFKVVSL LDLTEYEMCN
310 320 330 340 350
AVDEFLLLLD KGVYGLLYYA GHGYENFGNS FMVPVDAPNP YRSENCLCVQ
360 370 380 390 400
NILKLMQEKE TGLNVFLLDM CRKRNDYDDT IPILDALKVT ANIVFGYATC
410 420 430 440 450
QGAEAFEIQH SGLANGIFMK FLKDRLLEDK KITVLLDEVA EDMGKCHLTK
460 470 480 490 500
GRQALEIRSS LSEKRALTDP IQGAPCSAEA LVRNLQWAKA HELPESMCLK
510 520 530 540 550
FQCGVHIQLG FAAEFSNVMI IYTSIVHKPP EIIMCDAYVT DFPLDLDIDP
560 570 580 590 600
KHANKGTPEE TGSYLVSKEL PKHCLYTRLS SLQKLKEHLI FTVCLSYQYS
610 620 630 640 650
GLEDTVEEKQ EVSVGKPLIA KLDMHRGLGR KTCLQACPMP DETCHSSTST
660 670 680 690 700
SAGAGHFHSS QDSFHDVYHS QLGNSDSAMP PDRCHCSRTP HAFISNYPPH
710 720 730
HYCQFGRSNV PVETTDEMPF SFSDRLMISE N
Length:731
Mass (Da):82,161
Last modified:July 22, 2015 - v2
Checksum:iF941D03BA0434113
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07032326 Genomic DNA. No translation available.
RefSeqiXP_003751846.1. XM_003751798.3.
XP_003753105.1. XM_003753057.3.
UniGeneiRn.86215.

Genome annotation databases

EnsembliENSRNOT00000068418; ENSRNOP00000059281; ENSRNOG00000017181.
GeneIDi307366.
UCSCiRGD:1309195. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07032326 Genomic DNA. No translation available.
RefSeqiXP_003751846.1. XM_003751798.3.
XP_003753105.1. XM_003753057.3.
UniGeneiRn.86215.

3D structure databases

ProteinModelPortaliD4A980.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000059281.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000068418; ENSRNOP00000059281; ENSRNOG00000017181.
GeneIDi307366.
UCSCiRGD:1309195. rat.

Organism-specific databases

CTDi10892.
RGDi1309195. Malt1.

Phylogenomic databases

InParanoidiD4A980.
OMAiHPDNKEQ.
OrthoDBiEOG7673BH.
PhylomeDBiD4A980.
TreeFamiTF319744.

Enzyme and pathway databases

ReactomeiREACT_278187. FCERI mediated NF-kB activation.
REACT_318052. Activation of NF-kappaB in B cells.
REACT_342970. Downstream TCR signaling.
REACT_359556. CLEC7A (Dectin-1) signaling.
REACT_361089. CLEC7A/inflammasome pathway.

Miscellaneous databases

NextBioi657278.
PROiD4A980.

Gene expression databases

ExpressionAtlasiD4A980. baseline.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
2.60.40.10. 2 hits.
3.40.50.1460. 1 hit.
InterProiIPR029030. Caspase-like_dom.
IPR011029. DEATH-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003598. Ig_sub2.
IPR011600. Pept_C14_caspase.
IPR001309. Pept_C14_ICE_p20.
[Graphical view]
PfamiPF00656. Peptidase_C14. 1 hit.
[Graphical view]
SMARTiSM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50208. CASPASE_P20. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A980_RAT
AccessioniPrimary (citable) accession number: D4A980
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: July 22, 2015
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.