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D4A980 (D4A980_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length832 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSRNOP00000059281

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processB-1 B cell differentiation

Inferred from electronic annotation. Source: Ensembl

T cell proliferation

Inferred from electronic annotation. Source: Ensembl

T cell receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

activation of NF-kappaB-inducing kinase activity

Inferred from electronic annotation. Source: Ensembl

innate immune response

Inferred from electronic annotation. Source: Ensembl

nuclear export

Inferred from electronic annotation. Source: Ensembl

positive regulation of I-kappaB kinase/NF-kappaB signaling

Inferred from electronic annotation. Source: Ensembl

positive regulation of NF-kappaB transcription factor activity

Inferred from electronic annotation. Source: Ensembl

positive regulation of T cell activation

Inferred from electronic annotation. Source: Ensembl

positive regulation of T cell cytokine production

Inferred from electronic annotation. Source: Ensembl

positive regulation of interleukin-2 production

Inferred from electronic annotation. Source: Ensembl

protein oligomerization

Inferred from electronic annotation. Source: Ensembl

proteolysis

Inferred from electronic annotation. Source: Ensembl

regulation of T cell receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

regulation of apoptotic process

Inferred from electronic annotation. Source: Ensembl

response to fungus

Inferred from electronic annotation. Source: Ensembl

response to molecule of bacterial origin

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcytosol

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: Ensembl

protein complex

Inferred from electronic annotation. Source: Ensembl

   Molecular_functioncysteine-type endopeptidase activity

Inferred from electronic annotation. Source: InterPro

kinase activator activity

Inferred from electronic annotation. Source: Ensembl

signal transducer activity

Inferred from electronic annotation. Source: Ensembl

ubiquitin-protein ligase activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D4A980 [UniParc].

Last modified April 20, 2010. Version 1.
Checksum: 65100297A41CFFE9

FASTA83292,951
        10         20         30         40         50         60 
MSLWGQPLQA SPPPAVQQPL TASSGPSTAP PAGSTLNRLP EPLLRRLSES LDRAPEGRGW 

        70         80         90        100        110        120 
RQLAELAGSR GRLRLSCLDL EQCSLKVLEP EGSPSLCLLK LMGEKGCTVP ELSDFLQALE 

       130        140        150        160        170        180 
HTEVLQLLNP PGLKITVNPE SKAVLAGQFV KLCCRATGHP FVQYQWFKMN KEIPYGNSSE 

       190        200        210        220        230        240 
LIFNTVHVKD AGFYVCRVNN NSTFEFSQWS QLDVCDVTEV SDSFQGSLDG VSESKLRICV 

       250        260        270        280        290        300 
EPQSQKLAPG SALLLQCVAI GSPVPHYQWF KDESPLAHET KKHYTVPYVD LEHEGTYWCH 

       310        320        330        340        350        360 
VYNDRDSQDS KKVEIIIGRT DGAVECTEDE LNNLGRPDNK EQTGQPLAKD KVALLIGNMN 

       370        380        390        400        410        420 
YWEHPKLKAP LVDVYELTNL LRQLDFKVVS LLDLTEYEMC NAVDEFLLLL DKGVYGLLYY 

       430        440        450        460        470        480 
AGHGYENFGN SFMVPVDAPN PYRSENCLCV QNILKLMQEK ETGLNVFLLD MCRKRNDYDD 

       490        500        510        520        530        540 
TIPILDALKV TANIVFGYAT CQGAEAFEIQ HSGLANGIFM KFLKDRLLED KKITVLLDEV 

       550        560        570        580        590        600 
AEDMGKCHLT KGRQALEIRS SLSEKRALTD PIQGAPCSAE ALVRNLQWAK AHELPESMCL 

       610        620        630        640        650        660 
KFQCGVHIQL GFAAEFSNVM IIYTSIVHKP PEIIMCDAYV TDFPLDLDID PKHANKGTPE 

       670        680        690        700        710        720 
ETGSYLVSKE LPKHCLYTRL SSLQKLKEHL IFTVCLSYQY SGLEDTVEEK QEVSVGKPLI 

       730        740        750        760        770        780 
AKLDMHRGLG RKTCLQACPM PDETCHSSTS TSAGAGHFHS SQDSFHDVYH SQLGNSDSAM 

       790        800        810        820        830 
PPDRCHCSRT PHAFISNYPP HHYCQFGRSN VPVETTDEMP FSFSDRLMIS EN 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000059281.
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000059281.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABR06095569 Genomic DNA. No translation available.
RefSeqXP_003751846.1. XM_003751798.2.
XP_003753105.1. XM_003753057.2.
UniGeneRn.86215.

3D structure databases

ProteinModelPortalD4A980.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000068418; ENSRNOP00000059281; ENSRNOG00000017181.
GeneID307366.
KEGGrno:307366.
UCSCRGD:1309195. rat.

Organism-specific databases

CTD10892.
RGD1309195. Malt1.

Phylogenomic databases

GeneTreeENSGT00390000018044.
KOK07369.
OMAMNKEIPN.
OrthoDBEOG7673BH.
PhylomeDBD4A980.
TreeFamTF319744.

Family and domain databases

Gene3D1.10.533.10. 1 hit.
2.60.40.10. 2 hits.
InterProIPR011029. DEATH-like_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003598. Ig_sub2.
IPR011600. Pept_C14_caspase.
IPR001309. Pept_C14_ICE_p20.
[Graphical view]
PfamPF00656. Peptidase_C14. 1 hit.
[Graphical view]
SMARTSM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMSSF47986. SSF47986. 1 hit.
PROSITEPS50208. CASPASE_P20. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio657278.
PROD4A980.

Entry information

Entry nameD4A980_RAT
AccessionPrimary (citable) accession number: D4A980
Entry history
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: April 16, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)