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Protein
Submitted name:

MALT1 paracaspase

Gene

Malt1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-202424. Downstream TCR signaling.
R-RNO-2871837. FCERI mediated NF-kB activation.
R-RNO-5607764. CLEC7A (Dectin-1) signaling.
R-RNO-5660668. CLEC7A/inflammasome pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
MALT1 paracaspaseImported
Gene namesi
Name:Malt1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 18

Organism-specific databases

RGDi1309195. Malt1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD4A980.

Expressioni

Gene expression databases

BgeeiENSRNOG00000017181.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000059281.

Structurei

3D structure databases

SMRiD4A980.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 106Ig-likeInterPro annotationAdd BLAST77
Domaini135 – 213Ig-likeInterPro annotationAdd BLAST79
Domaini248 – 326CASPASE_P20InterPro annotationAdd BLAST79

Phylogenomic databases

eggNOGiENOG410IG3U. Eukaryota.
COG4249. LUCA.
GeneTreeiENSGT00390000018044.
InParanoidiD4A980.
OMAiHCLYTRL.
OrthoDBiEOG091G01PI.
TreeFamiTF319744.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiView protein in InterPro
IPR029030. Caspase-like_dom_sf.
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR033540. MALT1.
IPR001309. Pept_C14_p20.
PANTHERiPTHR22576:SF29. PTHR22576:SF29. 1 hit.
PfamiView protein in Pfam
PF13895. Ig_2. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 2 hits.
SM00408. IGc2. 2 hits.
SUPFAMiSSF48726. SSF48726. 2 hits.
SSF52129. SSF52129. 1 hit.
PROSITEiView protein in PROSITE
PS50208. CASPASE_P20. 1 hit.
PS50835. IG_LIKE. 2 hits.

Sequencei

Sequence statusi: Complete.

D4A980-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEKGCTVPE LSDFLQALEH TEVLQLLNPP GLKITVNPES KAVLAGQFVK
60 70 80 90 100
LCCRATGHPF VQYQWFKMNK EIPYGNSSEL IFNTVHVKDA GFYVCRVNNN
110 120 130 140 150
STFEFSQWSQ LDVCDVTEVS DSFQGSLDGV SESKLRICVE PQSQKLAPGS
160 170 180 190 200
ALLLQCVAIG SPVPHYQWFK DESPLAHETK KHYTVPYVDL EHEGTYWCHV
210 220 230 240 250
YNDRDSQDSK KVEIIIGRTD GAVECTEDEL NNLGRPDNKE QTGQPLAKDK
260 270 280 290 300
VALLIGNMNY WEHPKLKAPL VDVYELTNLL RQLDFKVVSL LDLTEYEMCN
310 320 330 340 350
AVDEFLLLLD KGVYGLLYYA GHGYENFGNS FMVPVDAPNP YRSENCLCVQ
360 370 380 390 400
NILKLMQEKE TGLNVFLLDM CRKRNDYDDT IPILDALKVT ANIVFGYATC
410 420 430 440 450
QGAEAFEIQH SGLANGIFMK FLKDRLLEDK KITVLLDEVA EDMGKCHLTK
460 470 480 490 500
GRQALEIRSS LSEKRALTDP IQGAPCSAEA LVRNLQWAKA HELPESMCLK
510 520 530 540 550
FQCGVHIQLG FAAEFSNVMI IYTSIVHKPP EIIMCDAYVT DFPLDLDIDP
560 570 580 590 600
KHANKGTPEE TGSYLVSKEL PKHCLYTRLS SLQKLKEHLI FTVCLSYQYS
610 620 630 640 650
GLEDTVEEKQ EVSVGKPLIA KLDMHRGLGR KTCLQACPMP DETCHSSTST
660 670 680 690 700
SAGAGHFHSS QDSFHDVYHS QLGNSDSAMP PDRCHCSRTP HAFISNYPPH
710 720 730
HYCQFGRSNV PVETTDEMPF SFSDRLMISE N
Length:731
Mass (Da):82,161
Last modified:July 22, 2015 - v2
Checksum:iF941D03BA0434113
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07032326 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000068418; ENSRNOP00000059281; ENSRNOG00000017181.
UCSCiRGD:1309195. rat.

Similar proteinsi

Entry informationi

Entry nameiD4A980_RAT
AccessioniPrimary (citable) accession number: D4A980
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: November 22, 2017
This is version 65 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported