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Protein
Submitted name:

N-acetylglutamate synthase

Gene

Nags

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei394SubstrateUniRule annotation1
Binding sitei437SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseSAAS annotation

Enzyme and pathway databases

ReactomeiR-RNO-70635. Urea cycle.

Names & Taxonomyi

Protein namesi
Submitted name:
N-acetylglutamate synthaseImported
Submitted name:
N-acetylglutamate synthase (Predicted), isoform CRA_aImported
Gene namesi
Name:NagsImported
Synonyms:Nags_predictedImported
ORF Names:rCG_34169Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1565783. Nags.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSRNOG00000020879.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028332.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini368 – 519N-acetyltransferaseInterPro annotationAdd BLAST152

Phylogenomic databases

eggNOGiKOG2436. Eukaryota.
COG0548. LUCA.
GeneTreeiENSGT00390000005602.
KOiK11067.
OMAiLTMEPVL.
OrthoDBiEOG091G0FPD.
TreeFamiTF332628.

Family and domain databases

InterProiView protein in InterPro
IPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR011243. GlcNAc_Synth_met.
IPR006855. Vertebrate-like_GNAT_dom.
PfamiView protein in Pfam
PF04768. NAT. 1 hit.
PIRSFiPIRSF036442. NAGS_animal. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiView protein in PROSITE
PS51731. GNAT_NAGS. 1 hit.

Sequencei

Sequence statusi: Complete.

D4A904-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAWVATAL RSAAAARRLR SPGGPGGSRR LSGSARRRGA RSASPGRRLS
60 70 80 90 100
TARAHVEDNE GTKGRVQSPA VEEPPWTPLP TPLESPAPPA GKSLVQRDIQ
110 120 130 140 150
AFLNQCGASP GEARHWLTQF QTCYHSVDKP FAVVEVDEEV FGCPQAVSRL
160 170 180 190 200
AFALAFLQRM DMKPLVVLGL PAPTAPSGCL SFWEAKAQLA QSCKVLVNEL
210 220 230 240 250
RHNAATAVPF FGGGSVLSAA EPAPHASYGG IVAVETDLLQ WCLESNSIPI
260 270 280 290 300
LCPIGETAAR RSVLLDSLEV TASLAKALQP TKIIFLNNSG GLRDTSQKIL
310 320 330 340 350
SNVNLPADLD LVTNAEWLST KERQQIRLIV DVLSRLPHYS SAVITAASTL
360 370 380 390 400
LTELFSNKGC GTLFKNAERM LRVRSLDSLD QGRLVNLVNA SFGKKLREDY
410 420 430 440 450
LESLRPRLHS IYVSEGYNAA AILTVEPVLG GTPYLDKFVV SSSRQGQGSG
460 470 480 490 500
QMLWECLRRD LQTLFWRSRV TNPINPWYFK HSDGSFSNKQ WIFFWFGLAD
510 520
IRDSYELVNH AKGLPDSFCK PASDPGS
Length:527
Mass (Da):57,421
Last modified:April 20, 2010 - v1
Checksum:iBAC78D8D84525116
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098160 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM06171.1.
RefSeqiNP_001100523.1. NM_001107053.1.
UniGeneiRn.23912.

Genome annotation databases

EnsembliENSRNOT00000028332; ENSRNOP00000028332; ENSRNOG00000020879.
GeneIDi303563.
KEGGirno:303563.
UCSCiRGD:1565783. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098160 Genomic DNA. No translation available.
CH473948 Genomic DNA. Translation: EDM06171.1.
RefSeqiNP_001100523.1. NM_001107053.1.
UniGeneiRn.23912.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028332.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028332; ENSRNOP00000028332; ENSRNOG00000020879.
GeneIDi303563.
KEGGirno:303563.
UCSCiRGD:1565783. rat.

Organism-specific databases

CTDi162417.
RGDi1565783. Nags.

Phylogenomic databases

eggNOGiKOG2436. Eukaryota.
COG0548. LUCA.
GeneTreeiENSGT00390000005602.
KOiK11067.
OMAiLTMEPVL.
OrthoDBiEOG091G0FPD.
TreeFamiTF332628.

Enzyme and pathway databases

ReactomeiR-RNO-70635. Urea cycle.

Gene expression databases

BgeeiENSRNOG00000020879.

Family and domain databases

InterProiView protein in InterPro
IPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR011243. GlcNAc_Synth_met.
IPR006855. Vertebrate-like_GNAT_dom.
PfamiView protein in Pfam
PF04768. NAT. 1 hit.
PIRSFiPIRSF036442. NAGS_animal. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiView protein in PROSITE
PS51731. GNAT_NAGS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD4A904_RAT
AccessioniPrimary (citable) accession number: D4A904
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 10, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.