D4A7V6 (D4A7V6_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein Casp8ap2 Ensembl ENSRNOP00000009227

Submitted name:
RCG55124 EMBL EDL98565.1

Gene names

Name:	Casp8ap2 Ensembl ENSRNOP00000009227
ORF Names:	rCG_55124 EMBL EDL98565.1

Organism

Rattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000009227

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	1962 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	extrinsic apoptotic signaling pathway via death domain receptors Inferred from electronic annotation. Source: Compara
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro cysteine-type endopeptidase activator activity involved in apoptotic process Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D4A7V6 [UniParc]. Last modified April 20, 2010. Version 1. Checksum: 76B0A27867A59CD1	FASTA	1,962	219,690
	10 20 30 40 50 60 MAADDDNGDG TGLFDVCPAS PLKNNDEGSL DIYAGLDSTV SDSTARSCVS FRNCLDLYEE 70 80 90 100 110 120 ILTEEGTAKE ATYSDLQIEY GKCQQQMKDL MKRFKEIQTQ NLNLKNENQS LKKNISALIK 130 140 150 160 170 180 TARVEINRKD EEINHLHQRL SEFPHFRNNH KTARTKDSRS KSPHLDNCSK TDHGVKSDVQ 190 200 210 220 230 240 KDIHPNTSQP NLEKEGKSHS EAQNSLHLST GIEKHCTNNV WSRSPYQVSE GNSNEDNRRG 250 260 270 280 290 300 RNGVRHSQGS RGTDRTQKDL NSSCNDGEPR DKEAASRLHG NPEKHGSSEA RAENKISEIK 310 320 330 340 350 360 SSTGLGNKSE RSASSWEKET SRERPHTRVE PQNDKNLERQ NERLQNTHRK ELQSQDKAER 370 380 390 400 410 420 KGDVKFKPAG EEQGHRGRVD RALPPHSKND MKYYGFNKYH PEERRGREDG KRDRGMSSHG 430 440 450 460 470 480 FQDRRCSSSL SSNRNSKYPH SKEVSVAHQW ENTPFKAERH RTEDRRKRER ENKEESRHVK 490 500 510 520 530 540 SDKKSPPEHL QRTHKDTKKS TANGKRQTEQ KHGKGPVSTS ELSKGTDNRE CTMKVENGPN 550 560 570 580 590 600 EAKGKDLKLS FMEKLNLTLS PAKKQPVCQD NEHQIIGVPK PSGVCDSQSL EKTETVACLP 610 620 630 640 650 660 SVSEQDREEP KSELPEPKEA LSATSQPRTS IPENKVKEEN RLLFKSVENT VPCELLACGT 670 680 690 700 710 720 EISFPAPVEI EQARCLVQSM EVEETCAGAR AAASVVMRVL PEHASEDFSQ ELGTKRHDDI 730 740 750 760 770 780 NSCDISEGGK KKVVLSPKAA AASESHLEPV VEEPSISPVN CSGDNNPKLE PSLEERPKVE 790 800 810 820 830 840 NKSSPLEPCL PKEMFVPSPQ KTELIDHKID TGESNSVYQD DDNSVLSIDF NNLRPIPEPI 850 860 870 880 890 900 SPLNSPVRPV SKVLSMESSC TIPLYDSSHK DEFPSNSTLS TFKSQSDLNK ENEKPVPKLD 910 920 930 940 950 960 KCSEAESCKN LSVDELEEGE IRSDDEESVA QKRLEKSARP RTSTEVPPGK ISPGSRRSTV 970 980 990 1000 1010 1020 HVHKDNGRTV VKLPRDRITW SQRSNESRPS NTERKSKTMS ISSLEKILPL ILAPSSVWEV 1030 1040 1050 1060 1070 1080 MHMLRLLGKH VRKNYMKFKI KFSLTQFHRI IESAILSFTS LIRYLDLSKI CKSVSTLQKS 1090 1100 1110 1120 1130 1140 LCDVIESNLK QVKKNGIVDR LFEQQQTDMK KKLWKFVDEQ LDYLFEKLKK ILLKFCDSVK 1150 1160 1170 1180 1190 1200 HENDSSEGKL GKKYKERAQH SNCQKKKMDN KEIRREKVLK SENTVNFKSS LGCEKFEEKH 1210 1220 1230 1240 1250 1260 QDQNKTNTTT VKHDVKRTFS TCTDNNTKNS ECKEQFLGMN CPSTPRPGET EGNVEEGTPA 1270 1280 1290 1300 1310 1320 AQHACVKSER GFEILTEQQA SSLTFNLVSD AQMGEIFKSL LQGSDLLDTG GTEKAEWELK 1330 1340 1350 1360 1370 1380 TPEKQLLESL KCESAPACTT EELVSEAASL CPKVISDDNW SLLSSEKGPS LSSGLSLPVH 1390 1400 1410 1420 1430 1440 PDVLDENCMF EVSSNLALSK DNVYSSEKSK PCISSILLED LAVSLTVPSP LKSDGHLSFL 1450 1460 1470 1480 1490 1500 KPEVLSTSTP EEVISAHFSE DALLEEEDAS EQDIHLALES DNSSSKSSCS SWTSRSVASG 1510 1520 1530 1540 1550 1560 FQYHPNLPMH AVIMEKSNDH FIVKIRRATP STSPGLKHGM VAEESLTPLP RTGKEADGAA 1570 1580 1590 1600 1610 1620 EKEPTLFQST VLNPVQDLEN SDKSIDKSKP THEDQNSIVQ TQVPDIYEFL KDASNKVVHC 1630 1640 1650 1660 1670 1680 DQVVDDCFKL HQVWEPKVSE SLQELPSMEK NAHSVDDHLP NTHIDLTKDP ATETKSLELM 1690 1700 1710 1720 1730 1740 DVTVLDIDHL EHSKPNLDQD AQITCTSLQH DAVDAFIDLT HDVSNESKNE SNEPVLTVEG 1750 1760 1770 1780 1790 1800 VGCQVICIDD DNHKEGKVGK VNSSLECTVE ETCIDLTSES AGSFEVKRHT LKSEPPSKSD 1810 1820 1830 1840 1850 1860 CLELPETLGN GHKKRKNSPA VSHSSQKKQR KDMDLSSEKT KRLSPNSDRT GDAHRKHGSK 1870 1880 1890 1900 1910 1920 KREPAVSDTS LSSEVNPEVK GSTAPLATFP GSLSAKNVIK KKGEIIVSWT RNDDREILLE 1930 1940 1950 1960 CQKRMPSLKT FTHLAVKLNK NPNQVSERFQ QLKKLFEKSK CR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the Brown Norway rat yields insights into mammalian evolution." Rat Genome Sequencing Project Consortium Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S. Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway Ensembl ENSRNOP00000009227.
[2]	"Gene and alternative splicing annotation with AIR." Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M., Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z., Istrail S., Li P., Sutton G. Genome Res. 15:54-66(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL98565.1.
[3]	Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M., Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F. , Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BN EMBL EDL98565.1.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Brown Norway Ensembl ENSRNOP00000009227.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABR06036354 Genomic DNA. No translation available. CH473962 Genomic DNA. Translation: EDL98565.1.
IPI	IPI00189403.
RefSeq	NP_001101391.1. NM_001107921.1.
UniGene	Rn.198715.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000009228; ENSRNOP00000009227; ENSRNOG00000006487.
GeneID	313128.
KEGG	rno:313128.
UCSC	RGD:1305771. rat.
Organism-specific databases
CTD	9994.
RGD	1305771. Casp8ap2.
Phylogenomic databases
GeneTree	ENSGT00620000088063.
OMA	EFPHFRN.
OrthoDB	EOG4VT5ZV.
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
InterPro	IPR009057. Homeodomain-like. [Graphical view]
ProtoNet	Search...
Other
NextBio	665683.

Entry information

Entry name

D4A7V6_RAT

Accession

Primary (citable) accession number: D4A7V6

Entry history

Integrated into UniProtKB/TrEMBL:	April 20, 2010
Last sequence update:	April 20, 2010
Last modified:	April 3, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)