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D4A7V6

- D4A7V6_RAT

UniProt

D4A7V6 - D4A7V6_RAT

Protein
Submitted name:

Protein Casp8ap2

Gene

Casp8ap2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (20 Apr 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cysteine-type endopeptidase activator activity involved in apoptotic process Source: Ensembl
    2. DNA binding Source: InterPro

    GO - Biological processi

    1. extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Casp8ap2Imported
    Submitted name:
    RCG55124Imported
    Gene namesi
    Name:Casp8ap2Imported
    ORF Names:rCG_55124Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 5

    Organism-specific databases

    RGDi1305771. Casp8ap2.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00620000088063.
    OMAiEKHCTNG.
    OrthoDBiEOG7J4460.
    TreeFamiTF332487.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    InterProiIPR009057. Homeodomain-like.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D4A7V6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAADDDNGDG TGLFDVCPAS PLKNNDEGSL DIYAGLDSTV SDSTARSCVS     50
    FRNCLDLYEE ILTEEGTAKE ATYSDLQIEY GKCQQQMKDL MKRFKEIQTQ 100
    NLNLKNENQS LKKNISALIK TARVEINRKD EEINHLHQRL SEFPHFRNNH 150
    KTARTKDSRS KSPHLDNCSK TDHGVKSDVQ KDIHPNTSQP NLEKEGKSHS 200
    EAQNSLHLST GIEKHCTNNV WSRSPYQVSE GNSNEDNRRG RNGVRHSQGS 250
    RGTDRTQKDL NSSCNDGEPR DKEAASRLHG NPEKHGSSEA RAENKISEIK 300
    SSTGLGNKSE RSASSWEKET SRERPHTRVE PQNDKNLERQ NERLQNTHRK 350
    ELQSQDKAER KGDVKFKPAG EEQGHRGRVD RALPPHSKND MKYYGFNKYH 400
    PEERRGREDG KRDRGMSSHG FQDRRCSSSL SSNRNSKYPH SKEVSVAHQW 450
    ENTPFKAERH RTEDRRKRER ENKEESRHVK SDKKSPPEHL QRTHKDTKKS 500
    TANGKRQTEQ KHGKGPVSTS ELSKGTDNRE CTMKVENGPN EAKGKDLKLS 550
    FMEKLNLTLS PAKKQPVCQD NEHQIIGVPK PSGVCDSQSL EKTETVACLP 600
    SVSEQDREEP KSELPEPKEA LSATSQPRTS IPENKVKEEN RLLFKSVENT 650
    VPCELLACGT EISFPAPVEI EQARCLVQSM EVEETCAGAR AAASVVMRVL 700
    PEHASEDFSQ ELGTKRHDDI NSCDISEGGK KKVVLSPKAA AASESHLEPV 750
    VEEPSISPVN CSGDNNPKLE PSLEERPKVE NKSSPLEPCL PKEMFVPSPQ 800
    KTELIDHKID TGESNSVYQD DDNSVLSIDF NNLRPIPEPI SPLNSPVRPV 850
    SKVLSMESSC TIPLYDSSHK DEFPSNSTLS TFKSQSDLNK ENEKPVPKLD 900
    KCSEAESCKN LSVDELEEGE IRSDDEESVA QKRLEKSARP RTSTEVPPGK 950
    ISPGSRRSTV HVHKDNGRTV VKLPRDRITW SQRSNESRPS NTERKSKTMS 1000
    ISSLEKILPL ILAPSSVWEV MHMLRLLGKH VRKNYMKFKI KFSLTQFHRI 1050
    IESAILSFTS LIRYLDLSKI CKSVSTLQKS LCDVIESNLK QVKKNGIVDR 1100
    LFEQQQTDMK KKLWKFVDEQ LDYLFEKLKK ILLKFCDSVK HENDSSEGKL 1150
    GKKYKERAQH SNCQKKKMDN KEIRREKVLK SENTVNFKSS LGCEKFEEKH 1200
    QDQNKTNTTT VKHDVKRTFS TCTDNNTKNS ECKEQFLGMN CPSTPRPGET 1250
    EGNVEEGTPA AQHACVKSER GFEILTEQQA SSLTFNLVSD AQMGEIFKSL 1300
    LQGSDLLDTG GTEKAEWELK TPEKQLLESL KCESAPACTT EELVSEAASL 1350
    CPKVISDDNW SLLSSEKGPS LSSGLSLPVH PDVLDENCMF EVSSNLALSK 1400
    DNVYSSEKSK PCISSILLED LAVSLTVPSP LKSDGHLSFL KPEVLSTSTP 1450
    EEVISAHFSE DALLEEEDAS EQDIHLALES DNSSSKSSCS SWTSRSVASG 1500
    FQYHPNLPMH AVIMEKSNDH FIVKIRRATP STSPGLKHGM VAEESLTPLP 1550
    RTGKEADGAA EKEPTLFQST VLNPVQDLEN SDKSIDKSKP THEDQNSIVQ 1600
    TQVPDIYEFL KDASNKVVHC DQVVDDCFKL HQVWEPKVSE SLQELPSMEK 1650
    NAHSVDDHLP NTHIDLTKDP ATETKSLELM DVTVLDIDHL EHSKPNLDQD 1700
    AQITCTSLQH DAVDAFIDLT HDVSNESKNE SNEPVLTVEG VGCQVICIDD 1750
    DNHKEGKVGK VNSSLECTVE ETCIDLTSES AGSFEVKRHT LKSEPPSKSD 1800
    CLELPETLGN GHKKRKNSPA VSHSSQKKQR KDMDLSSEKT KRLSPNSDRT 1850
    GDAHRKHGSK KREPAVSDTS LSSEVNPEVK GSTAPLATFP GSLSAKNVIK 1900
    KKGEIIVSWT RNDDREILLE CQKRMPSLKT FTHLAVKLNK NPNQVSERFQ 1950
    QLKKLFEKSK CR 1962
    Length:1,962
    Mass (Da):219,690
    Last modified:April 20, 2010 - v1
    Checksum:i76B0A27867A59CD1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06036354 Genomic DNA. No translation available.
    CH473962 Genomic DNA. Translation: EDL98565.1.
    RefSeqiNP_001101391.1. NM_001107921.1.
    XP_006238035.1. XM_006237973.1.
    XP_006238036.1. XM_006237974.1.
    XP_006238037.1. XM_006237975.1.
    UniGeneiRn.198715.

    Genome annotation databases

    EnsembliENSRNOT00000009228; ENSRNOP00000009227; ENSRNOG00000006487.
    GeneIDi313128.
    KEGGirno:313128.
    UCSCiRGD:1305771. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06036354 Genomic DNA. No translation available.
    CH473962 Genomic DNA. Translation: EDL98565.1 .
    RefSeqi NP_001101391.1. NM_001107921.1.
    XP_006238035.1. XM_006237973.1.
    XP_006238036.1. XM_006237974.1.
    XP_006238037.1. XM_006237975.1.
    UniGenei Rn.198715.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000009228 ; ENSRNOP00000009227 ; ENSRNOG00000006487 .
    GeneIDi 313128.
    KEGGi rno:313128.
    UCSCi RGD:1305771. rat.

    Organism-specific databases

    CTDi 9994.
    RGDi 1305771. Casp8ap2.

    Phylogenomic databases

    GeneTreei ENSGT00620000088063.
    OMAi EKHCTNG.
    OrthoDBi EOG7J4460.
    TreeFami TF332487.

    Miscellaneous databases

    NextBioi 665683.
    PROi D4A7V6.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    InterProi IPR009057. Homeodomain-like.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
      Hoffert J.D., Pisitkun T., Wang G., Shen R.F., Knepper M.A.
      Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiD4A7V6_RAT
    AccessioniPrimary (citable) accession number: D4A7V6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 20, 2010
    Last sequence update: April 20, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3