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D4A7V6

- D4A7V6_RAT

UniProt

D4A7V6 - D4A7V6_RAT

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Protein
Submitted name: Protein Casp8ap2
Gene
Casp8ap2, rCG_55124
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. cysteine-type endopeptidase activator activity involved in apoptotic process Source: Ensembl

GO - Biological processi

  1. extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Casp8ap2Imported
Submitted name:
RCG55124Imported
Gene namesi
Name:Casp8ap2Imported
ORF Names:rCG_55124Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 5

Organism-specific databases

RGDi1305771. Casp8ap2.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00620000088063.
OMAiEKHCTNG.
OrthoDBiEOG7J4460.
TreeFamiTF332487.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4A7V6-1 [UniParc]FASTAAdd to Basket

« Hide

MAADDDNGDG TGLFDVCPAS PLKNNDEGSL DIYAGLDSTV SDSTARSCVS     50
FRNCLDLYEE ILTEEGTAKE ATYSDLQIEY GKCQQQMKDL MKRFKEIQTQ 100
NLNLKNENQS LKKNISALIK TARVEINRKD EEINHLHQRL SEFPHFRNNH 150
KTARTKDSRS KSPHLDNCSK TDHGVKSDVQ KDIHPNTSQP NLEKEGKSHS 200
EAQNSLHLST GIEKHCTNNV WSRSPYQVSE GNSNEDNRRG RNGVRHSQGS 250
RGTDRTQKDL NSSCNDGEPR DKEAASRLHG NPEKHGSSEA RAENKISEIK 300
SSTGLGNKSE RSASSWEKET SRERPHTRVE PQNDKNLERQ NERLQNTHRK 350
ELQSQDKAER KGDVKFKPAG EEQGHRGRVD RALPPHSKND MKYYGFNKYH 400
PEERRGREDG KRDRGMSSHG FQDRRCSSSL SSNRNSKYPH SKEVSVAHQW 450
ENTPFKAERH RTEDRRKRER ENKEESRHVK SDKKSPPEHL QRTHKDTKKS 500
TANGKRQTEQ KHGKGPVSTS ELSKGTDNRE CTMKVENGPN EAKGKDLKLS 550
FMEKLNLTLS PAKKQPVCQD NEHQIIGVPK PSGVCDSQSL EKTETVACLP 600
SVSEQDREEP KSELPEPKEA LSATSQPRTS IPENKVKEEN RLLFKSVENT 650
VPCELLACGT EISFPAPVEI EQARCLVQSM EVEETCAGAR AAASVVMRVL 700
PEHASEDFSQ ELGTKRHDDI NSCDISEGGK KKVVLSPKAA AASESHLEPV 750
VEEPSISPVN CSGDNNPKLE PSLEERPKVE NKSSPLEPCL PKEMFVPSPQ 800
KTELIDHKID TGESNSVYQD DDNSVLSIDF NNLRPIPEPI SPLNSPVRPV 850
SKVLSMESSC TIPLYDSSHK DEFPSNSTLS TFKSQSDLNK ENEKPVPKLD 900
KCSEAESCKN LSVDELEEGE IRSDDEESVA QKRLEKSARP RTSTEVPPGK 950
ISPGSRRSTV HVHKDNGRTV VKLPRDRITW SQRSNESRPS NTERKSKTMS 1000
ISSLEKILPL ILAPSSVWEV MHMLRLLGKH VRKNYMKFKI KFSLTQFHRI 1050
IESAILSFTS LIRYLDLSKI CKSVSTLQKS LCDVIESNLK QVKKNGIVDR 1100
LFEQQQTDMK KKLWKFVDEQ LDYLFEKLKK ILLKFCDSVK HENDSSEGKL 1150
GKKYKERAQH SNCQKKKMDN KEIRREKVLK SENTVNFKSS LGCEKFEEKH 1200
QDQNKTNTTT VKHDVKRTFS TCTDNNTKNS ECKEQFLGMN CPSTPRPGET 1250
EGNVEEGTPA AQHACVKSER GFEILTEQQA SSLTFNLVSD AQMGEIFKSL 1300
LQGSDLLDTG GTEKAEWELK TPEKQLLESL KCESAPACTT EELVSEAASL 1350
CPKVISDDNW SLLSSEKGPS LSSGLSLPVH PDVLDENCMF EVSSNLALSK 1400
DNVYSSEKSK PCISSILLED LAVSLTVPSP LKSDGHLSFL KPEVLSTSTP 1450
EEVISAHFSE DALLEEEDAS EQDIHLALES DNSSSKSSCS SWTSRSVASG 1500
FQYHPNLPMH AVIMEKSNDH FIVKIRRATP STSPGLKHGM VAEESLTPLP 1550
RTGKEADGAA EKEPTLFQST VLNPVQDLEN SDKSIDKSKP THEDQNSIVQ 1600
TQVPDIYEFL KDASNKVVHC DQVVDDCFKL HQVWEPKVSE SLQELPSMEK 1650
NAHSVDDHLP NTHIDLTKDP ATETKSLELM DVTVLDIDHL EHSKPNLDQD 1700
AQITCTSLQH DAVDAFIDLT HDVSNESKNE SNEPVLTVEG VGCQVICIDD 1750
DNHKEGKVGK VNSSLECTVE ETCIDLTSES AGSFEVKRHT LKSEPPSKSD 1800
CLELPETLGN GHKKRKNSPA VSHSSQKKQR KDMDLSSEKT KRLSPNSDRT 1850
GDAHRKHGSK KREPAVSDTS LSSEVNPEVK GSTAPLATFP GSLSAKNVIK 1900
KKGEIIVSWT RNDDREILLE CQKRMPSLKT FTHLAVKLNK NPNQVSERFQ 1950
QLKKLFEKSK CR 1962
Length:1,962
Mass (Da):219,690
Last modified:April 20, 2010 - v1
Checksum:i76B0A27867A59CD1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06036354 Genomic DNA. No translation available.
CH473962 Genomic DNA. Translation: EDL98565.1.
RefSeqiNP_001101391.1. NM_001107921.1.
XP_006238035.1. XM_006237973.1.
XP_006238036.1. XM_006237974.1.
XP_006238037.1. XM_006237975.1.
UniGeneiRn.198715.

Genome annotation databases

EnsembliENSRNOT00000009228; ENSRNOP00000009227; ENSRNOG00000006487.
GeneIDi313128.
KEGGirno:313128.
UCSCiRGD:1305771. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06036354 Genomic DNA. No translation available.
CH473962 Genomic DNA. Translation: EDL98565.1 .
RefSeqi NP_001101391.1. NM_001107921.1.
XP_006238035.1. XM_006237973.1.
XP_006238036.1. XM_006237974.1.
XP_006238037.1. XM_006237975.1.
UniGenei Rn.198715.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000009228 ; ENSRNOP00000009227 ; ENSRNOG00000006487 .
GeneIDi 313128.
KEGGi rno:313128.
UCSCi RGD:1305771. rat.

Organism-specific databases

CTDi 9994.
RGDi 1305771. Casp8ap2.

Phylogenomic databases

GeneTreei ENSGT00620000088063.
OMAi EKHCTNG.
OrthoDBi EOG7J4460.
TreeFami TF332487.

Miscellaneous databases

NextBioi 665683.
PROi D4A7V6.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR009057. Homeodomain-like.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
    Hoffert J.D., Pisitkun T., Wang G., Shen R.F., Knepper M.A.
    Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A7V6_RAT
AccessioniPrimary (citable) accession number: D4A7V6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 3, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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