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D4A7V6

- D4A7V6_RAT

UniProt

D4A7V6 - D4A7V6_RAT

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Protein
Submitted name:

Protein Casp8ap2

Gene

Casp8ap2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. cysteine-type endopeptidase activator activity involved in apoptotic process Source: Ensembl
  2. DNA binding Source: InterPro

GO - Biological processi

  1. extrinsic apoptotic signaling pathway via death domain receptors Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Casp8ap2Imported
Submitted name:
RCG55124Imported
Gene namesi
Name:Casp8ap2Imported
ORF Names:rCG_55124Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 5

Organism-specific databases

RGDi1305771. Casp8ap2.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00620000088063.
OMAiEKHCTNG.
OrthoDBiEOG7J4460.
TreeFamiTF332487.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D4A7V6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAADDDNGDG TGLFDVCPAS PLKNNDEGSL DIYAGLDSTV SDSTARSCVS
60 70 80 90 100
FRNCLDLYEE ILTEEGTAKE ATYSDLQIEY GKCQQQMKDL MKRFKEIQTQ
110 120 130 140 150
NLNLKNENQS LKKNISALIK TARVEINRKD EEINHLHQRL SEFPHFRNNH
160 170 180 190 200
KTARTKDSRS KSPHLDNCSK TDHGVKSDVQ KDIHPNTSQP NLEKEGKSHS
210 220 230 240 250
EAQNSLHLST GIEKHCTNNV WSRSPYQVSE GNSNEDNRRG RNGVRHSQGS
260 270 280 290 300
RGTDRTQKDL NSSCNDGEPR DKEAASRLHG NPEKHGSSEA RAENKISEIK
310 320 330 340 350
SSTGLGNKSE RSASSWEKET SRERPHTRVE PQNDKNLERQ NERLQNTHRK
360 370 380 390 400
ELQSQDKAER KGDVKFKPAG EEQGHRGRVD RALPPHSKND MKYYGFNKYH
410 420 430 440 450
PEERRGREDG KRDRGMSSHG FQDRRCSSSL SSNRNSKYPH SKEVSVAHQW
460 470 480 490 500
ENTPFKAERH RTEDRRKRER ENKEESRHVK SDKKSPPEHL QRTHKDTKKS
510 520 530 540 550
TANGKRQTEQ KHGKGPVSTS ELSKGTDNRE CTMKVENGPN EAKGKDLKLS
560 570 580 590 600
FMEKLNLTLS PAKKQPVCQD NEHQIIGVPK PSGVCDSQSL EKTETVACLP
610 620 630 640 650
SVSEQDREEP KSELPEPKEA LSATSQPRTS IPENKVKEEN RLLFKSVENT
660 670 680 690 700
VPCELLACGT EISFPAPVEI EQARCLVQSM EVEETCAGAR AAASVVMRVL
710 720 730 740 750
PEHASEDFSQ ELGTKRHDDI NSCDISEGGK KKVVLSPKAA AASESHLEPV
760 770 780 790 800
VEEPSISPVN CSGDNNPKLE PSLEERPKVE NKSSPLEPCL PKEMFVPSPQ
810 820 830 840 850
KTELIDHKID TGESNSVYQD DDNSVLSIDF NNLRPIPEPI SPLNSPVRPV
860 870 880 890 900
SKVLSMESSC TIPLYDSSHK DEFPSNSTLS TFKSQSDLNK ENEKPVPKLD
910 920 930 940 950
KCSEAESCKN LSVDELEEGE IRSDDEESVA QKRLEKSARP RTSTEVPPGK
960 970 980 990 1000
ISPGSRRSTV HVHKDNGRTV VKLPRDRITW SQRSNESRPS NTERKSKTMS
1010 1020 1030 1040 1050
ISSLEKILPL ILAPSSVWEV MHMLRLLGKH VRKNYMKFKI KFSLTQFHRI
1060 1070 1080 1090 1100
IESAILSFTS LIRYLDLSKI CKSVSTLQKS LCDVIESNLK QVKKNGIVDR
1110 1120 1130 1140 1150
LFEQQQTDMK KKLWKFVDEQ LDYLFEKLKK ILLKFCDSVK HENDSSEGKL
1160 1170 1180 1190 1200
GKKYKERAQH SNCQKKKMDN KEIRREKVLK SENTVNFKSS LGCEKFEEKH
1210 1220 1230 1240 1250
QDQNKTNTTT VKHDVKRTFS TCTDNNTKNS ECKEQFLGMN CPSTPRPGET
1260 1270 1280 1290 1300
EGNVEEGTPA AQHACVKSER GFEILTEQQA SSLTFNLVSD AQMGEIFKSL
1310 1320 1330 1340 1350
LQGSDLLDTG GTEKAEWELK TPEKQLLESL KCESAPACTT EELVSEAASL
1360 1370 1380 1390 1400
CPKVISDDNW SLLSSEKGPS LSSGLSLPVH PDVLDENCMF EVSSNLALSK
1410 1420 1430 1440 1450
DNVYSSEKSK PCISSILLED LAVSLTVPSP LKSDGHLSFL KPEVLSTSTP
1460 1470 1480 1490 1500
EEVISAHFSE DALLEEEDAS EQDIHLALES DNSSSKSSCS SWTSRSVASG
1510 1520 1530 1540 1550
FQYHPNLPMH AVIMEKSNDH FIVKIRRATP STSPGLKHGM VAEESLTPLP
1560 1570 1580 1590 1600
RTGKEADGAA EKEPTLFQST VLNPVQDLEN SDKSIDKSKP THEDQNSIVQ
1610 1620 1630 1640 1650
TQVPDIYEFL KDASNKVVHC DQVVDDCFKL HQVWEPKVSE SLQELPSMEK
1660 1670 1680 1690 1700
NAHSVDDHLP NTHIDLTKDP ATETKSLELM DVTVLDIDHL EHSKPNLDQD
1710 1720 1730 1740 1750
AQITCTSLQH DAVDAFIDLT HDVSNESKNE SNEPVLTVEG VGCQVICIDD
1760 1770 1780 1790 1800
DNHKEGKVGK VNSSLECTVE ETCIDLTSES AGSFEVKRHT LKSEPPSKSD
1810 1820 1830 1840 1850
CLELPETLGN GHKKRKNSPA VSHSSQKKQR KDMDLSSEKT KRLSPNSDRT
1860 1870 1880 1890 1900
GDAHRKHGSK KREPAVSDTS LSSEVNPEVK GSTAPLATFP GSLSAKNVIK
1910 1920 1930 1940 1950
KKGEIIVSWT RNDDREILLE CQKRMPSLKT FTHLAVKLNK NPNQVSERFQ
1960
QLKKLFEKSK CR
Length:1,962
Mass (Da):219,690
Last modified:April 20, 2010 - v1
Checksum:i76B0A27867A59CD1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06036354 Genomic DNA. No translation available.
CH473962 Genomic DNA. Translation: EDL98565.1.
RefSeqiNP_001101391.1. NM_001107921.1.
XP_006238035.1. XM_006237973.2.
XP_006238036.1. XM_006237974.2.
XP_006238037.1. XM_006237975.2.
UniGeneiRn.198715.

Genome annotation databases

EnsembliENSRNOT00000009228; ENSRNOP00000009227; ENSRNOG00000006487.
GeneIDi313128.
KEGGirno:313128.
UCSCiRGD:1305771. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06036354 Genomic DNA. No translation available.
CH473962 Genomic DNA. Translation: EDL98565.1 .
RefSeqi NP_001101391.1. NM_001107921.1.
XP_006238035.1. XM_006237973.2.
XP_006238036.1. XM_006237974.2.
XP_006238037.1. XM_006237975.2.
UniGenei Rn.198715.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000009228 ; ENSRNOP00000009227 ; ENSRNOG00000006487 .
GeneIDi 313128.
KEGGi rno:313128.
UCSCi RGD:1305771. rat.

Organism-specific databases

CTDi 9994.
RGDi 1305771. Casp8ap2.

Phylogenomic databases

GeneTreei ENSGT00620000088063.
OMAi EKHCTNG.
OrthoDBi EOG7J4460.
TreeFami TF332487.

Miscellaneous databases

NextBioi 665683.
PROi D4A7V6.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
InterProi IPR009057. Homeodomain-like.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  4. "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
    Hoffert J.D., Pisitkun T., Wang G., Shen R.F., Knepper M.A.
    Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiD4A7V6_RAT
AccessioniPrimary (citable) accession number: D4A7V6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3